在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human PTB-containing, cubilin and LRP1-interacting protein (PID1)

  • 中文名稱:
    人PID1重組蛋白
  • 貨號:
    CSB-YP800096HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PID1重組蛋白
  • 貨號:
    CSB-EP800096HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PID1重組蛋白
  • 貨號:
    CSB-EP800096HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PID1重組蛋白
  • 貨號:
    CSB-BP800096HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PID1重組蛋白
  • 貨號:
    CSB-MP800096HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PID1
  • Uniprot No.:
  • 別名:
    5033414K04Rik; Ab1 119; FLJ20701; HMFN2073; MGC90850; NYGGF4; OTTHUMP00000164248; OTTHUMP00000204185; P CLI1; P-CLI1; PCLI1; PCLI1_HUMAN; Phosphotyrosine interaction domain containing 1; Phosphotyrosine interaction domain-containing protein 1; PID1; Protein NYGGF4; PTB containing; cubilin and LRP1 interacting protein; PTB-containing; cubilin and LRP1-interacting protein; RGD1560766
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-168
  • 氨基酸序列
    MWQPATERLQVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQ VWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVEC ESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVSQELESDDG
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Increases proliferation of preadipocytes without affecting adipocytic differentiation.
  • 基因功能參考文獻:
    1. Overall survival and radiation-free progression-free survival were longer in medulloblastoma patients whose tumors had higher PID1 mRNA levels. PMID: 24300787
    2. overexpression of TFAM can restore mitochondrial function to normal levels in NYGGF4-overexpressing adipocytes PMID: 23274913
    3. NYGGF4 plays a role in IR and its effects on IR could be reversed by metformin through activating IRS-1/PI3K/Akt and AMPK-PGC1-alpha pathways. PMID: 22968630
    4. NYGGF4 acts directly on the IRS1/PI3K/AKT insulin pathway to reduce glucose uptake and transport, impairs mitochondrial function and causes insulin resistance, and thus may be a useful therapeutic target for obesity-associated insulin resistance. PMID: 22284633
    5. Overexpression of NYGGF4 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of NYGGF4-induced insulin resistance. PMID: 20165904
    6. TNFA up-regulated the expression of NYGGF4 during preadipocyte differentiation. PMID: 20140872
    7. NYGGF4 over-expression impairs the insulin sensitivity of 3T3-L1 adipocytes through decreasing GLUT4 translocation and had no effects on the secretory function of adipocytes. PMID: 19849947
    8. A novel gene named NYGGF4, which was expressed at a higher level in obese subjects, was isolated and characterized and could play a role in cell growth and adipogenesis process PMID: 16815647
    9. Data show that NYGGF4 regulates the functions of IRS-1 and Akt, decreases GLUT4 translocation and reduces glucose uptake in response to insulin. PMID: 19079291
    10. Q7Z2X4 protein (PID1) identified as a cytosolic ligand of LRP1 in a trimeric complex with Cubilin. Q7Z2X4 named PCLI1 (PTB-containing, Cubilin and LRP1 Interacting protein 1) PMID: 17124247

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 組織特異性:
    Expressed in subcutaneous fat, heart, skeletal muscle, brain, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocyte.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 26084

    OMIM: 612930

    KEGG: hsa:55022

    STRING: 9606.ENSP00000375907

    UniGene: Hs.745038



主站蜘蛛池模板: 国产高清成人免费视频在线观看| 真实国产熟睡乱子伦视频| 免费无码一区二区三区a片百度| 躁躁躁日日躁| 久久www免费人成人片| 欧美特黄特色三级视频在线观看| 日韩少妇人妻vs中文字幕| 抽插丰满内射高潮视频| 国产日产欧产精品精品| 久久精品高清一区二区三区| 美女网站免费福利视频| 又大又长粗又爽又黄少妇视频| 国产欧美va欧美va香蕉在线观看| 天堂久久天堂av色综合| 久久精品国产网红主播| 四虎永久在线精品免费网站| 亚洲色成人网站www永久四虎| 国产亚洲精品久久久久小| 开心色怡人综合网站| 国产午夜福利精品久久2021| 国产精品一线二线三线| 国产日产欧产精品| 亚洲国产精品久久久久网站| 欧美丰满老妇性猛交| 国产一区二区三区成人欧美日韩在线观看| 毛片完整版的免费观看| 肉色丝袜足j视频国产| 少妇激情一区二区三区视频小说 | 120秒试看无码体验区| 国产精品无码午夜免费影院| 少妇高潮喷水久久久影院| 成人区精品一区二区不卡| 久久不见久久见免费影院视频 | 粉嫩大学生无套内射无码卡视频| 国产乱人无码伦av在线a| 日韩中文高清在线专区| 亚洲sm另类一区二区三区| 无码人妻丰满熟妇啪啪欧美| 久久精品a亚洲国产v高清不卡| 午夜福利啪啪无遮挡免费| 国产福利一区二区麻豆|