Recombinant Human PR domain zinc finger protein 8 (PRDM8)
-
中文名稱:人PRDM8重組蛋白
-
貨號:CSB-BP889084HU
-
規(guī)格:¥4164
-
圖片:
-
其他:
產(chǎn)品詳情
-
純度:Greater than 85% as determined by SDS-PAGE.
-
生物活性:Not Test
-
基因名:PRDM8
-
Uniprot No.:
-
別名:PR domain-containing protein 8
-
種屬:Homo sapiens (Human)
-
蛋白長度:Full Length
-
來源:Baculovirus
-
分子量:74.1 kDa
-
表達區(qū)域:1-689aa
-
氨基酸序列MEDTGIQRGIWDGDAKAVQQCLTDIFTSVYTTCDIPENAIFGPCVLSHTSLYDSIAFIALKSTDKRTVPYIFRVDTSAANGSSEGLMWLRLVQSARDKEEQNLEAYIKNGQLFYRSLRRIAKDEELLVWYGKELTELLLLCPSRSHNKMNGSSPYTCLECSQRFQFEFPYVAHLRFRCPKRLHSADISPQDEQGGGVGTKDHGGGGGGGKDQQQQQQEAPLGPGPKFCKAGPLHHYPSPSPESSNPSAAAGGSSAKPSTDFHNLARELENSRGGSSCSPAQSLSSGSGSGGGGGHQEAELSPDGIATGGGKGKRKFPEEAAEGGGGAGLVGGRGRFVERPLPASKEDLVCTPQQYRASGSYFGLEENGRLFAPPSPETGEAKRSAFVEVKKAARAASLQEEGTADGAGVASEDQDAGGGGGSSTPAAASPVGAEKLLAPRPGGPLPSRLEGGSPARGSAFTSVPQLGSAGSTSGGGGTGAGAAGGAGGGQGAASDERKSAFSQPARSFSQLSPLVLGQKLGALEPCHPADGVGPTRLYPAAADPLAVKLQGAADLNGGCGSLPSGGGGLPKQSPFLYATAFWPKSSAAAAAAAAAAAAGPLQLQLPSALTLLPPSFTSLCLPAQNWCAKCNASFRMTSDLVYHMRSHHKKEYAMEPLVKRRREEKLKCPICNESFRERHHLSRHMTSHN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering. -
蛋白標簽:Tag-Free
-
產(chǎn)品提供形式:Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
-
復溶:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
-
儲存條件:Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
-
保質(zhì)期:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期:Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
注意事項:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
-
Datasheet & COA:Please contact us to get it.
相關產(chǎn)品
靶點詳情
-
功能:Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival.
-
基因功能參考文獻:
- Aberrant hypermethylation is particularly observed in PRDM8 and this may support identification and classification of bone marrow failure syndromes PMID: 26909595
- alteration of hydroxymethylation and methylation of PRDM8 correlates with changes in its expression in the peripheral blood of children with DS. Given the proposed function of PRDM8 in cognitive disability in DS PMID: 27278638
-
相關疾病:Epilepsy, progressive myoclonic 10 (EPM10)
-
亞細胞定位:Nucleus.
-
蛋白家族:Class V-like SAM-binding methyltransferase superfamily
-
組織特異性:Expressed in brain, heart, skeletal muscle, testes, prostate.
-
數(shù)據(jù)庫鏈接:
Most popular with customers
-
Recombinant Human T-cell immunoreceptor with Ig and ITIM domains (TIGIT), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Leukemia inhibitory factor (LIF) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Tumor necrosis factor receptor superfamily member 9 (TNFRSF9), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human Nectin-4 (NECTIN4), partial (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Human B-lymphocyte antigen CD20 (MS4A1)-VLPs (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Rabbit Tissue factor pathway inhibitor (TFPI) (Active)
Express system: Mammalian cell
Species: Oryctolagus cuniculus (Rabbit)
-
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active)
Express system: Mammalian cell
Species: Homo sapiens (Human)
-
Recombinant Macaca mulatta Semaphorin-4D isoform 1 (SEMA4D), partial (Active)
Express system: Mammalian cell
Species: Macaca mulatta (Rhesus macaque)