在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human POU domain, class 5, transcription factor 1B (POU5F1B OCT4PG1 OTF3C OTF3P1 POU5F1P1 POU5FLC20 POU5FLC8)

  • 中文名稱:
  • 貨號:
    CSB-YP2312HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP2312HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP2312HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-BP2312HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-MP2312HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    P5F1B
  • Uniprot No.:
  • 別名:
    POU domain, class 5, transcription factor 1B; Oct4-pg1; Octamer-binding protein 3-like; Octamer-binding transcription factor 3-like; POU5F1B OCT4PG1 OTF3C OTF3P1 POU5F1P1 POU5FLC20 POU5FLC8
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Shows weak transcriptional activator activity.
  • 基因功能參考文獻:
    1. Study shows that irrespective of tumor type or clinicopathological status, breast cancer cells expressed high levels of Oct3/4 at mRNA and protein levels. Further sequencing analysis show that breast tumors and MCF-7 cell line predominantly expressed transcripts of POU5F1B, an Oct4-like gene from chromosome 8 which possess 94% similitude with oct-4. PMID: 29620155
    2. POU5F1B promotes hepatocellular carcinoma cell proliferation by activating AKT protein. PMID: 29454285
    3. We identified eight specific CpG sites at 8q24, including six correlated sites in the POU5F1B gene, as well as two CpG sites in intergenic regions, whose DNA methylation levels were associated with prostate cancer risk. PMID: 28463958
    4. The POU5F1B pseudogene is amplified and expressed at a high level in, as well as confers an aggressive phenotype on, GC, and that POU5F1B amplification is associated with a poor prognosis in GC patients. PMID: 24362523
    5. POU5F1P1 rs10505477 is correlated with survival of gastric cancer patients who receving cisplatin-based chemotherapy after gastrectomy. PMID: 25046748
    6. Association of rs7014346 in POU5F1P1, rs989902 in PTPN13, and rs7003146 in TCF7L2 with variations in the risk of breast cancer in a Chinese Han population. PMID: 24338422
    7. Data suggest that expression of Oct4 and NANOG (Nanog homeobox protein) is up-regulated in visceral adipose tissue stem cells in type 2 diabetes as compared to control; expression is also up-regulated in hyperglycemic conditions. PMID: 23064289
    8. Over-expression of POU5F1P1 in prostatic carcinoma in addition to its genomic location and the putative function of its gene product render POU5F1P1 a good candidate to harbour functional genetic variants which modulate prostatic cancer susceptibility. PMID: 20017164
    9. that a putative POU5F1P1 protein is localized in the nucleus, acts as a transcriptional activator and regulates the expression in a similar way to the POU5F1 isoform 1 PMID: 18949397

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    POU transcription factor family, Class-5 subfamily
  • 組織特異性:
    Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues.
  • 數據庫鏈接:

    HGNC: 9223

    OMIM: 615739

    KEGG: hsa:5462

    STRING: 9606.ENSP00000375557

    UniGene: Hs.450254



主站蜘蛛池模板: 国产av大陆精品一区二区三区 | 国产999精品成人网站| 精品国产18久久久久久| 久久免费午夜福利院| 亚洲高清无码加勒比| 中文字幕av无码免费久久| 久久精品无码专区免费| 亚洲乱码日产精品bd在线观看| 四虎亚洲欧美成人网站| 久久精品国产999久久久| 高中国产开嫩苞实拍视频在线观看 | 日本肥老妇色xxxxx日本老妇| 国产在线观看黄av免费| 成人h无码动漫超w网站| 鲁鲁狠狠狠7777一区二区| 真实的国产乱xxxx在线| 人妻丰满熟妇av无码区hd| 国产婷婷精品av在线| 国产三级在线观看播放| 中国丰满人妻videoshd| 免费无码不卡视频在线观看| 亚洲中文字幕在线无码一区二区| 中国xxx农村性视频| 无码成人精品区在线观看| av无码久久久久久不卡网站| 永久久久免费人妻精品| 亚洲色播永久网址大全| 亚洲精品99久久久久中文字幕| 亚洲精品成人无码中文毛片| 久久国产精品国产四虎90后| 国产高清在线a免费视频观看| 无码日韩人妻精品久久蜜桃 | 欲女熟妇国产一区二区| 大陆极品少妇内射aaaaaa| 女人下面毛多水多视频| 欧美成人精品三级网站视频| 国产精品成人精品久久久| 免费看男女做爰爽爽视频| 欧美乱码伦视频免费| 中文无码日韩欧av影视| 日韩人妻无码精品久久久不卡|