在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

POU5F1B Antibody, Biotin conjugated

  • 中文名稱:
    POU5F1B兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA23129D0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) POU5F1B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    class 5 antibody; Octamer-binding protein 3-like antibody; Octamer-binding transcription factor 3-like antibody; OTF3C antibody; OTF3P1 antibody; P5F1B_HUMAN antibody; POU5F1B antibody; POU5F1P1 antibody; POU5FLC20 antibody; POU5FLC8 antibody; Putative POU domain antibody; Putative POU domain, class 5, transcription factor 1B antibody; transcription factor 1B antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Putative POU domain, class 5, transcription factor 1B protein (10-138AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Shows weak transcriptional activator activity.
  • 基因功能參考文獻:
    1. Study shows that irrespective of tumor type or clinicopathological status, breast cancer cells expressed high levels of Oct3/4 at mRNA and protein levels. Further sequencing analysis show that breast tumors and MCF-7 cell line predominantly expressed transcripts of POU5F1B, an Oct4-like gene from chromosome 8 which possess 94% similitude with oct-4. PMID: 29620155
    2. POU5F1B promotes hepatocellular carcinoma cell proliferation by activating AKT protein. PMID: 29454285
    3. We identified eight specific CpG sites at 8q24, including six correlated sites in the POU5F1B gene, as well as two CpG sites in intergenic regions, whose DNA methylation levels were associated with prostate cancer risk. PMID: 28463958
    4. The POU5F1B pseudogene is amplified and expressed at a high level in, as well as confers an aggressive phenotype on, GC, and that POU5F1B amplification is associated with a poor prognosis in GC patients. PMID: 24362523
    5. POU5F1P1 rs10505477 is correlated with survival of gastric cancer patients who receving cisplatin-based chemotherapy after gastrectomy. PMID: 25046748
    6. Association of rs7014346 in POU5F1P1, rs989902 in PTPN13, and rs7003146 in TCF7L2 with variations in the risk of breast cancer in a Chinese Han population. PMID: 24338422
    7. Data suggest that expression of Oct4 and NANOG (Nanog homeobox protein) is up-regulated in visceral adipose tissue stem cells in type 2 diabetes as compared to control; expression is also up-regulated in hyperglycemic conditions. PMID: 23064289
    8. Over-expression of POU5F1P1 in prostatic carcinoma in addition to its genomic location and the putative function of its gene product render POU5F1P1 a good candidate to harbour functional genetic variants which modulate prostatic cancer susceptibility. PMID: 20017164
    9. that a putative POU5F1P1 protein is localized in the nucleus, acts as a transcriptional activator and regulates the expression in a similar way to the POU5F1 isoform 1 PMID: 18949397

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    POU transcription factor family, Class-5 subfamily
  • 組織特異性:
    Detected at the mRNA level in several cancer tissues (breast, uterine cervix, lung, thyroid gland, esophagus, colon, urinary bladder, and glioma), but absent in normal tissues.
  • 數據庫鏈接:

    HGNC: 9223

    OMIM: 615739

    KEGG: hsa:5462

    STRING: 9606.ENSP00000375557

    UniGene: Hs.450254



主站蜘蛛池模板: 亚洲熟妇丰满xxxxx| a∨变态另类天堂无码专区| 婷婷五月开心亚洲综合在线| 无人去码一码二码三码区| 少妇仑乱a毛片| 亚洲熟妇久久精品| 啊轻点内射在线视频| 色噜噜狠狠成人中文综合| 日韩少妇内射免费播放18禁裸乳 | 无码人妻丰满熟妇区bbbbxxxx | 偷看少妇自慰xxxx| 久久精品成人欧美大片| 日韩在线成年视频人网站观看| 亚洲精品高清无码视频| 大肉大捧一进一出好爽动态图| 国产强奷在线播放免费| 亚洲精品无码av中文字幕| 中文字幕乱码人妻综合二区三区| 婷婷色婷婷开心五月| 丰满人妻被黑人中出849| 成人乱码一区二区三区av| 色妞色视频一区二区三区四区| 国产精品自在自线视频| 日韩成人av无码一区二区三区| 国产午夜片无码区在线播放| 精品国产乱码久久久久软件| 十八禁午夜福利免费网站| 免费无遮挡无码视频在线观看| 国模叶桐尿喷337p人体| 亚洲欧美国产双大乳头| 午夜伦费影视在线观看| 成人永久免费网站在线观看 | 国产精品久久久久蜜芽| 国自产拍偷拍精品啪啪一区二区| 亚洲性视频免费视频网站| av人摸人人人澡人人超碰手机版| 欧美性白人极品hd| 国产97超碰人人做人人爱| 国产精品18久久久久久欧美| 国产乱人伦偷精品视频不卡| 婷婷五月综合激情中文字幕|