在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Oxysterol-binding protein-related protein 2 (OSBPL2)

  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-YP884442HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-EP884442HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-EP884442HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-BP884442HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-MP884442HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    OSBPL2
  • Uniprot No.:
  • 別名:
    FLJ20223; KIAA0772; MGC4307; MGC8342; ORP-2; ORP2; OSBL2_HUMAN; OSBP related protein 2; OSBP-related protein 2; OSBPL2; Oxysterol binding protein like 2; Oxysterol binding protein related protein 2; Oxysterol-binding protein-related protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-480
  • 氨基酸序列
    MNGEEEFFDA VTGFDSDNSS GEFSEANQKV TGMIDLDTSK NNRIGKTGER PSQENGIQKH RTSLPAPMFS RSDFSVWTIL KKCVGLELSK ITMPIAFNEP LSFLQRITEY MEHVYLIHRA SCQPQPLERM QSVAAFAVSA VASQWERTGK PFNPLLGETY ELIREDLGFR FISEQVSHHP PISAFHSEGL NHDFLFHGSI YPKLKFWGKS VEAEPRGTIT LELLKHNEAY TWTNPTCCVH NVIIGKLWIE QYGTVEILNH RTGHKCVLHF KPCGLFGKEL HKVEGHIQDK NKKKLFMIYG KWTECLWGID PVSYESFKKQ ERRGDHLRKA KLDEDSGKAD SDVADDVPVA QETVQVIPGS KLLWRINTRP PNSAQMYNFT SFTVSLNELE TGMEKTLPPT DCRLRPDIRG MENGNMDLAS QEKERLEEKQ REARRERAKE EAEWQTRWFY PGNNPYTGTP DWLYAGDYFE RNFSDCPDIY
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).
  • 基因功能參考文獻:
    1. point at a novel function of ORP2 as a lipid-sensing regulator of the actin cytoskeleton, with impacts on hepatocellular migration, adhesion, and proliferation PMID: 29092904
    2. this study identifies ORP2 as a new regulatory nexus of Akt signaling, cellular energy metabolism, actin cytoskeletal function, cell migration, and proliferation. PMID: 29947926
    3. a novel role for ORP2 in regulating steroidogenic capacity and cholesterol homeostasis in the adrenal cortex PMID: 26992564
    4. This study and the recent description of another frameshift mutation in a Chinese ADNSHL family identify OSBPL2 as a novel gene for progressive deafness. PMID: 25759012
    5. Results identified frameshift and missense mutation in OSBPL2 gene in familial and sporadic case of deafness suggesting OSBPL2 as a novel candidate gene for autosomal dominant nonsyndromic hearing loss . PMID: 25077649
    6. ORP2 as a novel regulator of cellular sterol homeostasis and intracellular membrane trafficking. PMID: 11861666
    7. Results identify ORP2 as a sterol receptor present on LD and provide evidence for its role in the regulation of neutral lipid metabolism, possibly as a factor that integrates the cellular metabolism of triglycerides with that of cholesterol. PMID: 19224871

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Deafness, autosomal dominant, 67 (DFNA67)
  • 亞細胞定位:
    Cytoplasm, cytosol. Lipid droplet. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    OSBP family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 15761

    OMIM: 606731

    KEGG: hsa:9885

    STRING: 9606.ENSP00000316649

    UniGene: Hs.473254



主站蜘蛛池模板: 亚洲成av人综合在线观看| 天天澡天天揉揉av在线| 亚洲中文字幕无码av| 国产影片av级毛片特别刺激| 久久爱www人成狠狠爱综合网| 国产亚洲精品自在久久蜜tv | 伦埋琪琪电影院久久| 久久久久人妻精品一区二区三区| 特黄 做受又硬又粗又大视频| 亚洲国产欧美国产综合久久| 少妇爽到呻吟的视频| 好爽好舒服要高潮了视频| 亚洲人成网线在线播放va蜜芽| 成人无码www免费视频| 东方aⅴ免费观看久久av| 国产美女裸体丝袜喷水视频| 国产一卡2卡3卡4卡精品| 欧美人与动牲交aⅴ| 特大巨黑吊xxxx高潮| 国产无线乱码一区二三区| 电影内射视频免费观看| 国内午夜熟妇又乱又伦| 国产欧美一区二区三区免费视频| 人妻体体内射精一区二区| 骚虎视频在线观看| 色综合亚洲一区二区小说| 亚洲精品伊人久久久大香| 无码人妻丝袜在线视频| 久久亚洲私人国产精品va| 久久香蕉国产线看观看手机| 人妻换着玩又刺激又爽| 欧美精品黑人粗大视频| 毛片24种姿势无遮无拦| 国产美女嘘嘘嘘嘘嘘| 九九久久精品国产免费看小说| 欧美人与牲动交xxxx| 无码人妻丰满熟妇啪啪| 尤物av无码国产在线看| 岛国无码av不卡一区二区| 久久久久久久综合狠狠综合| 久久高清内射无套|