在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Oxysterol-binding protein-related protein 2 (OSBPL2)

  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-YP884442HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-EP884442HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-EP884442HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-BP884442HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人OSBPL2重組蛋白
  • 貨號:
    CSB-MP884442HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    OSBPL2
  • Uniprot No.:
  • 別名:
    FLJ20223; KIAA0772; MGC4307; MGC8342; ORP-2; ORP2; OSBL2_HUMAN; OSBP related protein 2; OSBP-related protein 2; OSBPL2; Oxysterol binding protein like 2; Oxysterol binding protein related protein 2; Oxysterol-binding protein-related protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-480
  • 氨基酸序列
    MNGEEEFFDA VTGFDSDNSS GEFSEANQKV TGMIDLDTSK NNRIGKTGER PSQENGIQKH RTSLPAPMFS RSDFSVWTIL KKCVGLELSK ITMPIAFNEP LSFLQRITEY MEHVYLIHRA SCQPQPLERM QSVAAFAVSA VASQWERTGK PFNPLLGETY ELIREDLGFR FISEQVSHHP PISAFHSEGL NHDFLFHGSI YPKLKFWGKS VEAEPRGTIT LELLKHNEAY TWTNPTCCVH NVIIGKLWIE QYGTVEILNH RTGHKCVLHF KPCGLFGKEL HKVEGHIQDK NKKKLFMIYG KWTECLWGID PVSYESFKKQ ERRGDHLRKA KLDEDSGKAD SDVADDVPVA QETVQVIPGS KLLWRINTRP PNSAQMYNFT SFTVSLNELE TGMEKTLPPT DCRLRPDIRG MENGNMDLAS QEKERLEEKQ REARRERAKE EAEWQTRWFY PGNNPYTGTP DWLYAGDYFE RNFSDCPDIY
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).
  • 基因功能參考文獻:
    1. point at a novel function of ORP2 as a lipid-sensing regulator of the actin cytoskeleton, with impacts on hepatocellular migration, adhesion, and proliferation PMID: 29092904
    2. this study identifies ORP2 as a new regulatory nexus of Akt signaling, cellular energy metabolism, actin cytoskeletal function, cell migration, and proliferation. PMID: 29947926
    3. a novel role for ORP2 in regulating steroidogenic capacity and cholesterol homeostasis in the adrenal cortex PMID: 26992564
    4. This study and the recent description of another frameshift mutation in a Chinese ADNSHL family identify OSBPL2 as a novel gene for progressive deafness. PMID: 25759012
    5. Results identified frameshift and missense mutation in OSBPL2 gene in familial and sporadic case of deafness suggesting OSBPL2 as a novel candidate gene for autosomal dominant nonsyndromic hearing loss . PMID: 25077649
    6. ORP2 as a novel regulator of cellular sterol homeostasis and intracellular membrane trafficking. PMID: 11861666
    7. Results identify ORP2 as a sterol receptor present on LD and provide evidence for its role in the regulation of neutral lipid metabolism, possibly as a factor that integrates the cellular metabolism of triglycerides with that of cholesterol. PMID: 19224871

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Deafness, autosomal dominant, 67 (DFNA67)
  • 亞細胞定位:
    Cytoplasm, cytosol. Lipid droplet. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    OSBP family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 15761

    OMIM: 606731

    KEGG: hsa:9885

    STRING: 9606.ENSP00000316649

    UniGene: Hs.473254



主站蜘蛛池模板: 亚洲色无码中文字幕手机在线| 日韩在线不卡免费视频一区| 国产日产久久高清欧美一区 | 国产美女精品一区二区三区| 成熟丰满熟妇高潮xxxxx视频| 亚洲精品55夜色66夜色| 国产亚洲视频在线观看播放| 六十熟妇乱子伦视频 | 破了亲妺妺的处免费视频国产| 国产无遮挡aaa片爽爽| 狠狠色综合网站久久久久久久高清| 天天做天天大爽天天爱| 亚洲国产一区二区精品无码| 亚洲国产中文在线视频| 538在线精品视频| 亚洲色成人www永久网站| 99久久国产自偷自偷免费一区| 久久人人超碰精品caoporen| 无码喷水一区二区浪潮av| 宅男噜噜噜66网站在线观看| 午夜福利国产成人无码gif动图| 狠狠躁夜夜躁人人爽天天古典| 亚洲天堂在线观看完整版| 亚洲综合区图片小说区| 国产午夜福利短视频| 精品人妻中文字幕有码在线| 特黄做受又大又粗又长大片| 久久午夜无码鲁丝片直播午夜精品 | 中文字幕卡二和卡三的视频 | 中文 在线 日韩 亚洲 欧美| 92精品成人国产在线观看| 少妇精品无码一区二区免费视频| 狠狠色噜噜狠狠狠8888米奇| 国产yw8825免费观看网站| 日本一区二区三区免费播放视频站| 四库影院永久四虎精品国产| 中文字幕乱码亚洲无线三区| 人禽杂交18禁网站免费| 亚洲国产激情一区二区三区| 99精品国产一区二区三区a片| 久久久久久九九99精品|