在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OSBPL2 Antibody

  • 中文名稱:
    OSBPL2兔多克隆抗體
  • 貨號:
    CSB-PA017248GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    OSBPL2
  • 別名:
    FLJ20223 antibody; KIAA0772 antibody; MGC4307 antibody; MGC8342 antibody; ORP-2 antibody; ORP2 antibody; OSBL2_HUMAN antibody; OSBP related protein 2 antibody; OSBP-related protein 2 antibody; OSBPL2 antibody; Oxysterol binding protein like 2 antibody; Oxysterol binding protein related protein 2 antibody; Oxysterol-binding protein-related protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human OSBPL2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).
  • 基因功能參考文獻:
    1. point at a novel function of ORP2 as a lipid-sensing regulator of the actin cytoskeleton, with impacts on hepatocellular migration, adhesion, and proliferation PMID: 29092904
    2. this study identifies ORP2 as a new regulatory nexus of Akt signaling, cellular energy metabolism, actin cytoskeletal function, cell migration, and proliferation. PMID: 29947926
    3. a novel role for ORP2 in regulating steroidogenic capacity and cholesterol homeostasis in the adrenal cortex PMID: 26992564
    4. This study and the recent description of another frameshift mutation in a Chinese ADNSHL family identify OSBPL2 as a novel gene for progressive deafness. PMID: 25759012
    5. Results identified frameshift and missense mutation in OSBPL2 gene in familial and sporadic case of deafness suggesting OSBPL2 as a novel candidate gene for autosomal dominant nonsyndromic hearing loss . PMID: 25077649
    6. ORP2 as a novel regulator of cellular sterol homeostasis and intracellular membrane trafficking. PMID: 11861666
    7. Results identify ORP2 as a sterol receptor present on LD and provide evidence for its role in the regulation of neutral lipid metabolism, possibly as a factor that integrates the cellular metabolism of triglycerides with that of cholesterol. PMID: 19224871

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Deafness, autosomal dominant, 67 (DFNA67)
  • 亞細胞定位:
    Cytoplasm, cytosol. Lipid droplet. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    OSBP family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 15761

    OMIM: 606731

    KEGG: hsa:9885

    STRING: 9606.ENSP00000316649

    UniGene: Hs.473254



主站蜘蛛池模板: 人狥杂交一区欧美二区| 色视频www在线播放国产人成| 亚洲自偷自拍另类11p| 国产东北肥熟老胖女| 久久久久久九九99精品 | 女人爽到高潮免费视频大全| 国产二级一片内射视频播放| 成 人 亚洲 综合天堂| 92国产精品午夜福利无毒不卡| 思思99热久久精品在线6| 性视频播放免费视频| 久久久精品人妻一区二区三区 | 女人爽到高潮视频免费直播| 中国精学生妹品射精久久| 中文字幕人妻熟女在线 | 婷婷久久香蕉五月综合| 最新亚洲伦理中文字幕| 欧美另类bbbxxxxx另类| 国产精品偷伦视频免费观看了 | 激情综合婷婷丁香五月情 | 57pao成人国产永久免费视频| 玩弄人妻少妇500系列网址| 免费va人成视频网站全| 亚洲精品成人网站在线| 国产伦孑沙发午休精品| 山东熟女啪啪哦哦叫| 国产亚洲精品福利在线无卡一| 国产偷国产偷亚洲清高孕妇| 久久婷婷成人综合色综合| 人妻有码av中文字幕久久琪| av无码东京热亚洲男人的天堂| 亚洲欧洲自偷自拍图片| 成 人 网 站 免费 在线| 99久久久无码国产精品不卡| 色翁荡息又大又硬又粗又爽电影| 丁香五月激情综合国产| 在线播放亚洲人成电影| 精品人妻无码一区二区色欲产成人 | 天天爽夜夜爱| 樱花草在线社区www韩国 | 欧美大香线蕉线伊人久久|