在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Opioid growth factor receptor (OGFR)

  • 中文名稱:
    人OGFR重組蛋白
  • 貨號(hào):
    CSB-EP016311HU
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    OGFR
  • Uniprot No.:
  • 別名:
    7 60 protein; HGNC:15768; Met enkephalin receptor; OGFr; OGFR_HUMAN; Opioid growth factor receptor; Protein 7-60; Zeta Opioid Receptor; Zeta type opioid receptor; Zeta-type opioid receptor
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    80.8 kDa
  • 表達(dá)區(qū)域:
    1-677aa
  • 氨基酸序列
    MDDPDCDSTWEEDEEDAEDAEDEDCEDGEAAGARDADAGDEDEESEEPRAARPSSFQSRMTGSRNWRATRDMCRYRHNYPDLVERDCNGDTPNLSFYRNEIRFLPNGCFIEDILQNWTDNYDLLEDNHSYIQWLFPLREPGVNWHAKPLTLREVEVFKSSQEIQERLVRAYELMLGFYGIRLEDRGTGTVGRAQNYQKRFQNLNWRSHNNLRITRILKSLGELGLEHFQAPLVRFFLEETLVRRELPGVRQSALDYFMFAVRCRHQRRQLVHFAWEHFRPRCKFVWGPQDKLRRFKPSSLPHPLEGSRKVEEEGSPGDPDHEASTQGRTCGPEHSKGGGRVDEGPQPRSVEPQDAGPLERSQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEGAGDSAAVASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRDEPAKAGEAAELQDAEVESSAKSGKP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.
  • 基因功能參考文獻(xiàn):
    1. Morphine interacts with OGFR and may suppress lung cancer proliferation and progression. PMID: 27167686
    2. The blockade of OGF signaling by MNTX releases cells from their arrest and boosts the effect of Doc PMID: 25853862
    3. The OGF-OGFr axis may be a feasible target for treatment of cancer of the ovary (i) in a prophylactic fashion, (ii) following cytoreduction or (iii) in conjunction with standard chemotherapy for additive effectiveness PMID: 23856908
    4. OGF-OGFr axis is a determinant of the progression of human ovarian cancer PMID: 22328595
    5. These data are the first to report that theOGFr system is a native biological regulator of cell proliferation in Hepatocellular carcinoma PMID: 19923357
    6. OGF and OGFR are present in follicular-derived thyroid cancers, and that OGF serves in a inhibitory manner to maintain homeostasis of cell proliferation. PMID: 19835629
    7. Gene therapy to reinstate more OGFr and enhance OGFr function, could serve as a useful treatment for inhibiting tumor progression in head and neck cancers. PMID: 16685459
    8. Opioid growth factor receptor is unaltered with the progression of human pancreatic and colon cancers PMID: 16820893
    9. These data indicate that the OGF receptor is integral to cell replication of SCCHN, and support treatment modalities that amplify OGFr in order to decrease the growth of these neoplasias. PMID: 17273790
    10. supports opioid growth factor receptor (OGFr) gene function as a regulator of cell proliferation that impacts on tumorigenic expression, and suggest that molecular and pharmacological manipulation of OGFr may prevent or delay human pancreatic cancer. PMID: 18636152
    11. Results indicate that both p16(INK4a) and p21(WAF1/CIP1) are required for the opioid growth factor (OGF)-OGF receptor axis to inhibit cell proliferation in normal cells. PMID: 18923142
    12. the regulation of cell proliferation by the OGF-OGFr axis is dependent on nucleocytoplasmic translocation and reliant on the integrity of two NLSs in OGFr to interact with transport receptors. PMID: 19244545
    13. Cell proliferation of human ovarian cancer is regulated by the opioid growth factor-opioid growth factor receptor axis. PMID: 19297547
    14. Opioid growth factor-opioid growth factor receptor axis is a physiological determinant of cell proliferation in diverse human cancers. PMID: 19675283

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Note=The OGF/OGFR complex is probably translocated to the nucleus.
  • 蛋白家族:
    Opioid growth factor receptor family
  • 組織特異性:
    Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15768

    OMIM: 606459

    KEGG: hsa:11054

    STRING: 9606.ENSP00000290291

    UniGene: Hs.67896



主站蜘蛛池模板: 久久人人97超碰超国产| 青草内射中出高潮| 好男人日本社区www| 无码人妻丝袜视频在线播免费| 亚洲精品gv天堂无码男同| 成人午夜福利视频后入| 人妻丰满被色诱中文字幕 | 天天摸夜夜添夜夜无码| 美女内射毛片在线看免费人动物| 久久人妻无码中文字幕| 亚洲youwu永久无码精品| 亚洲人成在线观看网站无码| 少妇被躁爽到高潮无码久久| 日躁夜躁狠狠躁2001| 日本真人边吃奶边做爽动态图| 小草社区视频在线观看| 中文字幕人成乱码熟女| 色悠久久久久综合网香蕉| 自拍校园亚洲欧美另类| 免费1级做爰片在线观看爱| 国产精品亚韩精品无码a在线| 1000部精品久久久久久久久 | 日本丶国产丶欧美色综合| 宅宅少妇无码| 日韩精品一区二区三区影院 | 亚洲小说图区综合在线| 国精产品69永久中国有限| 少妇人妻偷人精品视频| 综合无码一区二区三区| 中文乱码免费一区二区| 夜夜欢性恔真人免费视频| 性色av无码不卡中文字幕| 国产av仑乱内谢| 欧美18精品久久久无码午夜福利| 97se亚洲国产综合自在线| 国产成人精品日本亚洲网站| 无码一区二区波多野结衣播放搜索| 精品午夜福利在线视在亚洲| 精品免费看国产一区二区| 久久国产欧美日韩精品| 性无码专区无码片|