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Recombinant Human Odorant-binding protein 2a (OBP2A) (C114S,K127N)

In Stock
  • 中文名稱:
    人OBP2A重組蛋白
  • 貨號(hào):
    CSB-EP873688HU(M)
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    OBP2A
  • Uniprot No.:
  • 別名:
    (Odorant-binding protein IIa)(OBPIIa)
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    30.8 kDa
  • 表達(dá)區(qū)域:
    16-170aa(C114S,K127N)
  • 氨基酸序列
    LSFTLEEEDITGTWYVKAMVVDKDFPEDRRPRKVSPVKVTALGGGNLEATFTFMREDRCIQKKILMRKTEEPGKFSAYGGRKLIYLQELPGTDDYVFYSKDQRRGGLRYMGNLVGRNPNTNLEALEEFKKLVQHKGLSEEDIFMPLQTGSCVLEH
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids.
  • 基因功能參考文獻(xiàn):
    1. This study demonstrated that the OBPIIa is associated with bitter sensitivity in human. PMID: 28487220
    2. Studied the crystallographic structure of human odorant-binding protein, OBPIIa at 2.6 A resolution. PMID: 25810031
    3. hOBPIIa(alpha) is expressed in the nasal mucus covering the olfactory cleft and is able to bind numerous odorants of diverse chemical structures, with a higher affinity for aldehydes and large fatty acids. PMID: 12044155
    4. Lys112 is the major determinant for governing hOBP-2A specificity towards aldehydes and small carboxylic acids. PMID: 16546182
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Calycin superfamily, Lipocalin family
  • 組織特異性:
    Strongly expressed in the nasal structures, salivary and lachrymal glands, and lung.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 23380

    OMIM: 164320

    KEGG: hsa:29991

    STRING: 9606.ENSP00000360841

    UniGene: Hs.567489



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