在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human O-phosphoseryl-tRNA (Sec) selenium transferase (SEPSECS)

  • 中文名稱:
    人SEPSECS重組蛋白
  • 貨號:
    CSB-YP888032HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SEPSECS重組蛋白
  • 貨號:
    CSB-EP888032HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SEPSECS重組蛋白
  • 貨號:
    CSB-BP888032HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SEPSECS重組蛋白
  • 貨號:
    CSB-MP888032HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    DKFZp434B1417; Liver pancreas antigen; Liver-pancreas antigen; LP; MGC161491; O phosphoseryl tRNA(Sec) selenium transferase; O-phosphoseryl-tRNA(Sec) selenium transferase; Sec synthase; Selenocysteine synthase; Selenocysteinyl tRNA(Sec) synthase; Selenocysteinyl-tRNA(Sec) synthase; Sep (O phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase; Sep tRNA:Sec tRNA synthase; Sep-tRNA:Sec-tRNA synthase; SepSecS; SLA; SLA p35; SLA-p35; SLA/LP; SLA/LP autoantigen; Soluble liver antigen; Soluble liver antigen/liver pancreas antigen; Soluble Liver/Pancreas Antigen; SPCS_HUMAN; tRNA(Ser/Sec) associated antigenic protein; tRNA(Ser/Sec)-associated antigenic protein; TRNP48; UGA suppressor tRNA associated protein; UGA suppressor tRNA-associated protein
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-501
  • 氨基酸序列
    MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD IEEMALKLDN VLLDTYQDAS S
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
  • 基因功能參考文獻:
    1. Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase has been described. PMID: 27576344
    2. Epileptic encephalopathy with burst suppression without brain malformations is associated with pathogenic variation in SEPSECS. PMID: 28133863
    3. The progression of clinical symptoms in these families is evidently slower than in previously reported cases, and the cerebellar atrophy milder by brain MRI, indicating that SEPSECS mutations are also involved in milder late-onset cerebellar atrophy. PMID: 26888482
    4. results suggest SEPSECS as a candidate gene for progressive encephalopathies with lactate elevation. PMID: 26115735
    5. structural analysis of the terminal catalytic complex in selenocysteine synthesis PMID: 25190812
    6. Data suggest SEPSECS silencing in placental trophoblasts inhibits proliferation, induces apoptosis, and reduces production of progesterone/chorionic gonadotropin (P/hCG); SEPSECS over-expression promotes cell proliferation and secretion of P/hCG. PMID: 23966103
    7. The human SepSecS protein is also known as soluble liver antigen/liver pancreas (SLA/LP), which represents one of the antigens of autoimmune hepatitis. PMID: 20623998
    8. SepSecS mutations cause autosomal-recessive progressive cerebellocerebral atrophy in Jews of Iraqi and Moroccan ancestry. PMID: 20920667
    9. detectable in liver extracts of autoimmune hepatitis patients' cells as the major autoantigenic component PMID: 19683415
    10. crystal structure of tRNA(Sec) in complex with SepSecS, phosphoserine, and thiophosphate, together with in vivo and in vitro enzyme assays, supports a pyridoxal phosphate-dependent mechanism of Sec-tRNA(Sec) formation PMID: 19608919

    顯示更多

    收起更多

  • 相關疾病:
    Pontocerebellar hypoplasia 2D (PCH2D)
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    SepSecS family
  • 組織特異性:
    Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.
  • 數據庫鏈接:

    HGNC: 30605

    OMIM: 613009

    KEGG: hsa:51091

    STRING: 9606.ENSP00000371535

    UniGene: Hs.253305



主站蜘蛛池模板: 欧美成人a在线网站| 国产成在线观看免费视频| 国产精品白丝av网站| 久久久久av无码免费网| 久久精品aⅴ无码中文字字幕重口 亚洲精品永久在线观看 | 国内乱码一线二线三线| 无码人妻h动漫中文字幕| 2021国产精品午夜久久| 亚洲日韩aⅴ在线视频| 国产人妻aⅴ色偷| 精品日本一区二区免费视频| 中文字幕亚洲综合久久青草| 成人aaa片一区国产精品| 精品无码一区二区三区电影| 中日韩精品卡一卡二卡3卡| 日韩亚洲欧美精品综合| 国产又粗又猛又大爽又黄| www片香蕉内射在线88av8| 在线 亚洲 国产 欧美| 69国产成人精品午夜福中文| 国产乱人伦中文无无码视频试看 | 亚洲国产成人久久久网站| 精品国产午夜理论片不卡精品 | 丰满少妇弄高潮了www| 亚洲精品日本一区二区三区| 人人爽人人澡人人人妻、百度| 色噜噜狠狠狠狠色综合久一| 97精品人妻一区二区三区香蕉| 人人爽久久涩噜噜噜av| 亚洲男男无套gv大学生| 久久丫精品忘忧草西安产品| 国产精品亚洲一区二区三区喷水 | 欧美牲交视频免费观看 | 国产日韩av免费无码一区二区三区| 无码人妻丰满熟妇区五十路百度| 久久久水蜜桃国产成人网站| 巨爆乳中文字幕巨爆区巨爆乳无码| 亚州av综合色区无码一区| 亚洲国产精品无码久久一线| 亚洲性av网站| 熟妇人妻中文字幕|