在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Nuclear receptor coactivator 5 (NCOA5)

  • 中文名稱:
    人NCOA5重組蛋白
  • 貨號:
    CSB-YP015544HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NCOA5重組蛋白
  • 貨號:
    CSB-EP015544HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NCOA5重組蛋白
  • 貨號:
    CSB-EP015544HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NCOA5重組蛋白
  • 貨號:
    CSB-BP015544HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NCOA5重組蛋白
  • 貨號:
    CSB-MP015544HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    NCOA5
  • Uniprot No.:
  • 別名:
    NCOA5; KIAA1637; Nuclear receptor coactivator 5; NCoA-5; Coactivator independent of AF-2; CIA
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-579
  • 氨基酸序列
    MNTAPSRPSP TRRDPYGFGD SRDSRRDRSP IRGSPRREPR DGRNGRDARD SRDIRDPRDL RDHRHSRDLR DHRDSRSVRD VRDVRDLRDF RDLRDSRDFR DQRDPMYDRY RDMRDSRDPM YRREGSYDRY LRMDDYCRRK DDSYFDRYRD SFDGRGPPGP ESQSRAKERL KREERRREEL YRQYFEEIQR RFDAERPVDC SVIVVNKQTK DYAESVGRKV RDLGMVVDLI FLNTEVSLSQ ALEDVSRGGS PFAIVITQQH QIHRSCTVNI MFGTPQEHRN MPQADAMVLV ARNYERYKNE CREKEREEIA RQAAKMADEA ILQERERGGP EEGVRGGHPP AIQSLINLLA DNRYLTAEET DKIINYLRER KERLMRSSTD SLPGPISRQP LGATSGASLK TQPSSQPLQS GQVLPSATPT PSAPPTSQQE LQAKILSLFN SGTVTANSSS ASPSVAAGNT PNQNFSTAAN SQPQQRSQAS GNQPPSILGQ GGSAQNMGPR PGAPSQGLFG QPSSRLAPAS NMTSQRPVSS TGINFDNPSV QKALDTLIQS GPALSHLVSQ TTAQMGQPQA PMGSYQRHY
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2).
  • 基因功能參考文獻:
    1. knockout of NCOA5 can suppress the epithelial - mesenchymal transition (EMT) in hepatocellular carcinoma cells. PMID: 29626478
    2. This study provides new insights and evidences that NOCA5 over-expression was significantly correlated with progression and prognosis in luminal breast cancer. However, the precise cellular mechanisms for NOCA5 in luminal breast cancer need to be further explored. PMID: 27847318
    3. NCOA5 low expression correlates with survival in esophageal squamous cell carcinoma. PMID: 25416054
    4. suggest that NCOA5 is a haploinsufficient tumor suppressor and that NCOA5 deficiency increases susceptibility to both glucose intolerance and HCC, partially by increasing IL-6 expression PMID: 24332041
    5. gene polymorphism confers susceptibility to psoriasis in a Southern European population PMID: 21645569

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 15909

    KEGG: hsa:57727

    STRING: 9606.ENSP00000290231

    UniGene: Hs.654991



主站蜘蛛池模板: 亚在线第一国产州精品99| 少妇放荡的呻吟干柴烈火免费视频| 亚瑟国产精品久久| 波多野结衣在线播放| 特级无码毛片免费视频尤物| 亚洲日本一区二区三区在线播放| 久久国产偷任你爽任你| 亚洲精品综合一区二区| 国产精品久久久久久久久久| 爆乳女仆高潮在线观看| 欧美大浪妇猛交饥渴大叫| 欧美高清精品一区二区| 人妻av无码系列专区移动可看 | 日本亚洲欧洲无免费码在线| 中文字幕无线码免费人妻| 亚洲欧洲成人av每日更新 | 亚洲精品无码永久中文字幕| 最新国产av无码专区亚洲| 韩国乱码伦视频免费| 亚洲欧洲专线一区| 末发育女av片一区二区| 成熟老妇女毛茸茸的做性 | 色视频综合无码一区二区三区| 婷婷综合缴情亚洲狠狠小说| 最近中文字幕在线中文视频| 熟妇人妻无码中文字幕老熟妇 | 欧美老熟妇乱子| 精品日本一区二区三区在线观看| 东北少妇不戴套对白第一次| 两性色午夜视频免费老司机| 亚洲一卡2卡3卡4卡精品| 欧美特级特黄aaaaaa在线看| 亚洲欧美在线人成最新| 综合无码精品人妻一区二区三区| 一边捏奶一边高潮视频| 亚洲人成电影在线观看影院| 日韩人妻无码精品一专区| 人人玩人人添人人澡欧美| 亚洲成av人最新无码| 免费国精产品自偷自偷免费看| 亚洲va中文字幕无码久久|