在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Neuronal acetylcholine receptor subunit beta-3 (CHRNB3)

Recombinant Human Neuronal acetylcholine receptor subunit beta-3 (CHRNB3)

  • 中文名稱：
  • 貨號(hào)：
    CSB-YP005397HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-EP005397HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-EP005397HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-BP005397HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-MP005397HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ACHB3
  • Uniprot No.：
  • 別名：
    Neuronal acetylcholine receptor subunit beta-3 CHRNB3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

相關(guān)產(chǎn)品

靶點(diǎn)詳情

  • 功能：
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 基因功能參考文獻(xiàn)：
    1. To gain a better understanding of the pathological processes underlying ND and ND-related behaviors and to promote the development of effective smoking cessation therapies, we here present the most recent studies concerning the genetic effects of the CHRNB3-CHRNA6 gene cluster in ND. PMID: 27327258
    2. More low frequency variants in the CHRNA6/CHRNB3 gene region were observed in cases compared to controls. PMID: 27085880
    3. Data provide evidence that the protective genetic variant at rs6474413 identified in human genetic studies reduces gene expression and that decreased beta3 gene expression in mice reduces nicotine intake PMID: 26318101
    4. This patient's chromosomal abnormality affected only one gene that is highly expressed in the brainstem and brain, involved in neurotransmission, and could be related to her Duane retraction syndrome. PMID: 24001015
    5. the CHRNB3-A6 locus contains multiple variants affecting risk for vulnerability to cocaine and nicotine dependence as well as bipolar disorder, suggesting that they have pleiotropic effects. PMID: 24675634
    6. Polymorphism in CHRNB3 gene is associated with esophageal adenocarcinoma. PMID: 25823894
    7. The common variant rs13273442 in the CHRNB3-CHNRA6 region is associated significantly with nicotine dependence in European Americans and African Americans. PMID: 24401102
    8. CHRNB3 c.-57A>G alteration affects the promoter activity and is associated with Parkinson's disease (PD), and smoking in PD patients. PMID: 24731518
    9. this study provides convincing evidence for a role of CHRNB3 in Nicotine Dependence. PMID: 23319001
    10. these results demonstrate that the combined effect of rs6474412-C/T polymorphism in smoking-related CHRNB3-CHRNA6 region gene and smoking behavior may not confer risk to psoriasis vulgaris (PV), but may have impact on PV severity in Chinese Han population. PMID: 24792900
    11. Results demonstrate the association between SNPs in CHRNB3 nicotinic acetylcholine receptor genes and the risk of smoking in ADHD PMID: 23899432
    12. The results indicate the genetic locus for the CHRNB3 gene is strongly associated with nicotine dependence. PMID: 22524403
    13. beta3 subunit coexpression promotes function of alpha6*-nAChR PMID: 22315221
    14. Variants in CHRNB3/CHRNA6 are independently associated with bipolar disorder. PMID: 21191315
    15. The GG genotype of SNP rs13261190 in the CHRNB3 was associated with increased novelty seeking in alcohol-dependent individuals. PMID: 21606657
    16. CHRNB3 and CHRNA6 polymorphisms are associated with smoking behavior and lung cancer susceptibility in Chinese Han population. PMID: 21831805
    17. Three single nucleotide polymorphisms (SNPs) in CHRNA6 and one SNP in CHRNB3 are associated with a composite of alcohol phenotypes. PMID: 19500157
    18. CHRNB3-CHRNA6 and CYP2A6 sequence variants affect smoking behavior PMID: 20418888
    19. CHRNB3 is associated with subjective responses to tobacco. PMID: 18055561
    20. Together these results further implicate the region downstream of CHRNA6 and the region upstream of CHRNB3 in risk of nicotine dependence. PMID: 18704094

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Beta-3/CHRNB3 sub-subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1963

    OMIM: 118508

    KEGG: hsa:1142

    STRING: 9606.ENSP00000289957

    UniGene: Hs.654576



主站蜘蛛池模板： 樱桃视频影视在线观看免费| 亚洲美女视频高清在线看| 久草热8精品视频在线观看 | 伊人久久大香线蕉综合狠狠| 久久久久麻豆v国产精华液好用吗| 黑鬼大战白妞高潮喷白浆| 国产超碰人人爱被ios解锁| 女被啪到深处喷水gif动态图| 农村乱人伦一区二区| 国产成人无码www免费视频播放| 日韩伦人妻无码| av片日韩一区二区三区在线观看| 色综合天天综合网国产成人网 | 无尺码精品产品网站| 亚洲大尺度无码无码专线一区| 国产一区二区三区免费高清在线播放 | 美女av一区二区三区| 国产丝袜在线精品丝袜不卡| 婷婷色五月开心五月| 亚洲色欲色欱www在线| 国产精品美脚玉足脚交欧美 | 亚洲天天做日日做天天欢毛片| 99久久99久久精品免费看蜜桃| 亚洲在线国产日韩欧美| 久久99国产综合精品女同| 国产精品厕所| 国产精品久久国产三级国| 亚洲日韩性欧美中文字幕| 久久99九九精品久久久久蜜桃 | 国产亚洲精品久久久性色情软件| 人妻性奴波多野结衣无码| 欧美一区二区三区| 99久久久无码国产精品秋霞网 | 久久成人网站亚洲综合| 日韩av高清在线看片| 国产xxxx做受性欧美88| 18禁超污无遮挡无码网址| 国产精品久久久久久福利| 国产午夜三级一区二区三| 无码三级av电影在线观看| 男女无遮挡激情视频|