在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Neuronal acetylcholine receptor subunit beta-3 (CHRNB3)

Recombinant Human Neuronal acetylcholine receptor subunit beta-3 (CHRNB3)

  • 中文名稱：
  • 貨號(hào)：
    CSB-YP005397HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-EP005397HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-EP005397HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-BP005397HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
  • 貨號(hào)：
    CSB-MP005397HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ACHB3
  • Uniprot No.：
  • 別名：
    Neuronal acetylcholine receptor subunit beta-3 CHRNB3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

相關(guān)產(chǎn)品

靶點(diǎn)詳情

  • 功能：
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 基因功能參考文獻(xiàn)：
    1. To gain a better understanding of the pathological processes underlying ND and ND-related behaviors and to promote the development of effective smoking cessation therapies, we here present the most recent studies concerning the genetic effects of the CHRNB3-CHRNA6 gene cluster in ND. PMID: 27327258
    2. More low frequency variants in the CHRNA6/CHRNB3 gene region were observed in cases compared to controls. PMID: 27085880
    3. Data provide evidence that the protective genetic variant at rs6474413 identified in human genetic studies reduces gene expression and that decreased beta3 gene expression in mice reduces nicotine intake PMID: 26318101
    4. This patient's chromosomal abnormality affected only one gene that is highly expressed in the brainstem and brain, involved in neurotransmission, and could be related to her Duane retraction syndrome. PMID: 24001015
    5. the CHRNB3-A6 locus contains multiple variants affecting risk for vulnerability to cocaine and nicotine dependence as well as bipolar disorder, suggesting that they have pleiotropic effects. PMID: 24675634
    6. Polymorphism in CHRNB3 gene is associated with esophageal adenocarcinoma. PMID: 25823894
    7. The common variant rs13273442 in the CHRNB3-CHNRA6 region is associated significantly with nicotine dependence in European Americans and African Americans. PMID: 24401102
    8. CHRNB3 c.-57A>G alteration affects the promoter activity and is associated with Parkinson's disease (PD), and smoking in PD patients. PMID: 24731518
    9. this study provides convincing evidence for a role of CHRNB3 in Nicotine Dependence. PMID: 23319001
    10. these results demonstrate that the combined effect of rs6474412-C/T polymorphism in smoking-related CHRNB3-CHRNA6 region gene and smoking behavior may not confer risk to psoriasis vulgaris (PV), but may have impact on PV severity in Chinese Han population. PMID: 24792900
    11. Results demonstrate the association between SNPs in CHRNB3 nicotinic acetylcholine receptor genes and the risk of smoking in ADHD PMID: 23899432
    12. The results indicate the genetic locus for the CHRNB3 gene is strongly associated with nicotine dependence. PMID: 22524403
    13. beta3 subunit coexpression promotes function of alpha6*-nAChR PMID: 22315221
    14. Variants in CHRNB3/CHRNA6 are independently associated with bipolar disorder. PMID: 21191315
    15. The GG genotype of SNP rs13261190 in the CHRNB3 was associated with increased novelty seeking in alcohol-dependent individuals. PMID: 21606657
    16. CHRNB3 and CHRNA6 polymorphisms are associated with smoking behavior and lung cancer susceptibility in Chinese Han population. PMID: 21831805
    17. Three single nucleotide polymorphisms (SNPs) in CHRNA6 and one SNP in CHRNB3 are associated with a composite of alcohol phenotypes. PMID: 19500157
    18. CHRNB3-CHRNA6 and CYP2A6 sequence variants affect smoking behavior PMID: 20418888
    19. CHRNB3 is associated with subjective responses to tobacco. PMID: 18055561
    20. Together these results further implicate the region downstream of CHRNA6 and the region upstream of CHRNB3 in risk of nicotine dependence. PMID: 18704094

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Beta-3/CHRNB3 sub-subfamily
  • 數(shù)據(jù)庫鏈接：

    HGNC: 1963

    OMIM: 118508

    KEGG: hsa:1142

    STRING: 9606.ENSP00000289957

    UniGene: Hs.654576



主站蜘蛛池模板： 国产熟妇与子伦hd| 好疼太大了太粗太长了视频 | 久久不见久久见www电影免费| 国产av丝袜一区二区三区| av中文无码韩国亚洲色偷偷| 亚洲色欧美色2019在线| 老熟妻内射精品一区| 国产绳艺sm调教室论坛| 国模国产精品嫩模大尺度视频 | 麻豆精产一二三产区| 人人澡人人澡人人看添| 与子敌伦刺激对白播放| 精品人妻无码专区在线无广告视频| 国产av久久人人澡人人爱| 欧美日韩亚洲国产综合乱| 无码少妇一区二区性色av| 欧美大浪妇猛交饥渴大叫| 亚洲欧美国产双大乳头| 色老99久久精品偷偷鲁| 色偷偷av亚洲男人的天堂| 久久aⅴ无码av高潮av喷吹 | 久久成人影院精品99| 在线观看片免费人成视频无码| 亚洲一区二区三区播放| 欧美乱妇狂野欧美在线视频| 日韩国产精品无码一区二区三区 | 精品高朝久久久久9999| 亚洲色无码中文字幕在线| 人妻少妇精品无码专区动漫| 伊人久久综合成人网| 日韩制服国产精品一区| 国产男女猛烈无遮挡免费视频网站| 亚洲人成在线观看| 亚洲va天堂va欧美ⅴa在线| 国产午夜av秒播在线观看| 日韩精品视频一区二区三区| 国内少妇偷人精品免费| 亚洲精品久久66国产高清| 亚洲精品无播放器在线播放| 亚洲毛片不卡av在线播放一区| 又大又粗又爽又黄的少妇毛片 |