在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Neuroblastoma-amplified sequence (NBAS), partial

  • 中文名稱:
    人NBAS重組蛋白
  • 貨號:
    CSB-YP015481HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人NBAS重組蛋白
  • 貨號:
    CSB-EP015481HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人NBAS重組蛋白
  • 貨號:
    CSB-EP015481HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人NBAS重組蛋白
  • 貨號:
    CSB-BP015481HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人NBAS重組蛋白
  • 貨號:
    CSB-MP015481HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    NBAS
  • Uniprot No.:
  • 別名:
    NBAS; NBAS_HUMAN; Neuroblastoma-amplified gene protein; Neuroblastoma-amplified sequence
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER.
  • 基因功能參考文獻:
    1. NBAS was the only candidate gene mutated in more than one patient. All NBAS mutations were novel and predictedly pathogenic. Of these mutations, 3 lay in distal (C-terminal) regions of NBAS, a novel distribution. Unlike the 2 patients without NBAS mutations, the 3 patients with confirmed NBAS mutations all suffered from a febrile illness before each episode of liver crisis (fever-related recurrent acute liver failure) PMID: 28629372
    2. The age of the mutation in Yakutia was estimated to be about 804 +/- 140 years. The frequency of heterozygous carriers of mutation G5741-->A (R1914H) in gene NBAS was found, which averaged 13 per 1000 healthy Yakuts PMID: 29369590
    3. variants in NBAS, are reported as a cause of bone fragility in humans, and expand the phenotypic spectrum associated with NBAS. PMID: 27789416
    4. A novel compound heterozygous mutations of NBAS (NM_015909.3): c.680A > C (p.His227Pro) were identified in two siblings with acute liver failure. PMID: 28576691
    5. NBAS mutations cause a multisystem disorder involving bone, connective tissue, liver, immune system, and retina. PMID: 26286438
    6. Biallelic Mutations in NBAS Cause Recurrent Acute Liver Failure with Onset in Infancy. PMID: 26073778
    7. DHX34 and NBAS act in concert with core nonsense-mediated mRNA decay factors to co-regulate a large number of endogenous RNA targets. PMID: 23828042
    8. These findings suggest that function of NBAS may associate with the pathogenesis of short stature syndrome as well as optic atrophy and Pelger-Huet anomaly. PMID: 20577004
    9. There may be a subset of NB in which enhanced DDX1 and low-NAG expression consequent to DDX1 co-amplification without NAG amplification contributes to susceptibility to intensive therapy. PMID: 17028906
    10. Results together suggest that NAG links between p31 and ZW10-RINT-1 and is involved in Golgi-to-ER transport. PMID: 19369418
    11. Defects in NAG-ELMO1 is associated with leukemic progression. PMID: 19407829

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH); Infantile liver failure syndrome 2 (ILFS2)
  • 亞細胞定位:
    Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein.
  • 組織特異性:
    Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblas
  • 數據庫鏈接:

    HGNC: 15625

    OMIM: 608025

    KEGG: hsa:51594

    STRING: 9606.ENSP00000281513

    UniGene: Hs.467759



主站蜘蛛池模板: 真实国产乱子伦精品一区二区三区| 九一九色国产| 天天狠天天添日日拍| 国产午夜aaaaa片在线影院| 毛片免费视频肛交颜射免费视频 | 成年无码av片| a毛片终身免费观看网站| 亚洲成本人无码薄码区| 欧美国产综合欧美视频| 欧美一区二区三区| 精品国产午夜理论片不卡精品| 夜夜澡人摸人人添人人看 | 亚洲 欧美 唯美 国产 伦 综合| 亚洲2020天天堂在线观看| 好紧好爽好湿别拔出来视频男男| 人妻少妇中文字幕久久| 国产精品9999久久久久| 亚洲国产成人精品无码一区二区| 欧美又粗又长又爽做受| 黑森林福利视频导航| 欧美日韩在大午夜爽爽影院| 蜜臀视频一区二区在线播放| 无码国产激情在线观看 | 欧美精品黑人粗大免费| 人人鲁人人莫人人爱精品| 久久久久波多野结衣高潮| 一区二区三区四区在线 | 欧洲| 亚洲国产成人精品福利| 好男人社区www在线官网| 亚洲日本va午夜中文字幕一区| 精品免费国产一区二区三区四区介绍 | 浪货趴办公桌~h揉秘书电影| 被c到高潮疯狂喷水国产| 在线成人a毛片免费播放| 高大丰满熟妇丰满的大白屁股 | 国产真实露脸乱子伦原著| 成人性生交片无码免费看| 国产高颜值大学生情侣酒店| 婷婷丁香五月缴情视频| 欧美变态另类牲交| 狠狠色狠狠人格综合|