在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human N-arachidonyl glycine receptor (GPR18), partial

  • 中文名稱:
    人GPR18重組蛋白
  • 貨號:
    CSB-YP614525HU1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GPR18重組蛋白
  • 貨號:
    CSB-EP614525HU1
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GPR18重組蛋白
  • 貨號:
    CSB-EP614525HU1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GPR18重組蛋白
  • 貨號:
    CSB-BP614525HU1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GPR18重組蛋白
  • 貨號:
    CSB-MP614525HU1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    GPR18; GPCRW; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Receptor for endocannabinoid N-arachidonyl glycine (NAGly). However, conflicting results about the role of NAGly as an agonist are reported. Can also be activated by plant-derived and synthetic cannabinoid agonists. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant. Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure. Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis.
  • 基因功能參考文獻:
    1. Results indicate that G protein-coupled receptor 18 (GPR18) might be involved in physiological processes of spermatozoa, suggesting GPR18 to be a potential player in sperm physiology. PMID: 27572937
    2. A novel RvD2-GPR18 resolution axis stimulates human and mouse phagocyte functions to control bacterial infections and promote organ protection. PMID: 26195725
    3. the results presented herein provide further evidence for GPR18 as a candidate cannabinoid receptor PMID: 24762058
    4. GPR18, the most abundantly overexpressed orphan G-protein-coupled receptor in all melanoma metastases, is constitutively active and inhibits apoptosis, indicating an important role for GPR18 in tumor cell survival. PMID: 20880198
    5. N-arachidonylglycine is a natural ligand for GPR18 PMID: 16844083

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in midpiece of spermatozoon (at protein level). Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4472

    OMIM: 602042

    KEGG: hsa:2841

    STRING: 9606.ENSP00000343428

    UniGene: Hs.741589



主站蜘蛛池模板: 98久久人妻少妇激情啪啪| 日韩欧美猛交xxxxx无码| 精品不卡一区二区| 爽死你欧美大白屁股在线| av网站的免费观看| 日本黄网站免费| 午夜成人理论福利片| 亚洲熟女乱综合一区二区在线| 国产系列丝袜熟女精品网站| 国产日韩一区二区三区在线观看| 男女做爰真人视频直播| 夜夜爽狠狠天天婷婷五月| 在线视频国产网址你懂的| 免费毛儿一区二区十八岁| 亚洲日韩精品欧美一区二区一 | 欧美日韩不卡高清在线看| 亚洲日本乱码一区二区产线一∨| 欧美黑人乱大交| 小说区 图片区色 综合区| 日本妇人成熟免费| 华人在线亚洲欧美精品| 国产午夜福利不卡在线秋霞秋霞| 欧美xxxx做受性欧美88| 高潮内射免费看片| 日本午夜免a费看大片中文4| 午夜不卡无码中文字幕影院| 老熟女重囗味hdxx69| 国产精品成人亚洲777| 人人超碰人人超级碰国| 亚洲国产中文在线二区三区免| 天天做天天爱天天综合网2021 | 久久天天躁狠狠躁夜夜爽| 久久久久国色av免费看| 久国产精品人妻aⅴ| 精品成人毛片一区二区| 久久婷婷香蕉热狠狠综合| 两根大肉大捧一进一出好爽视频| 日韩免费无码人妻波多野| 欧美丰满熟妇bbb久久久| 欲香欲色天天天综合和网| 国产成人美女裸体片免费看|