在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPR18 Antibody, FITC conjugated

GPR18 Antibody, FITC conjugated

  • 中文名稱：
    GPR18兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA614525LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GPR18 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GPR18; GPCRW; N-arachidonyl glycine receptor; NAGly receptor; G-protein coupled receptor 18
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human N-arachidonyl glycine receptor protein (290-331AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for endocannabinoid N-arachidonyl glycine (NAGly). However, conflicting results about the role of NAGly as an agonist are reported. Can also be activated by plant-derived and synthetic cannabinoid agonists. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system. Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant. Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure. Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis.
  • 基因功能參考文獻：
    1. Results indicate that G protein-coupled receptor 18 (GPR18) might be involved in physiological processes of spermatozoa, suggesting GPR18 to be a potential player in sperm physiology. PMID: 27572937
    2. A novel RvD2-GPR18 resolution axis stimulates human and mouse phagocyte functions to control bacterial infections and promote organ protection. PMID: 26195725
    3. the results presented herein provide further evidence for GPR18 as a candidate cannabinoid receptor PMID: 24762058
    4. GPR18, the most abundantly overexpressed orphan G-protein-coupled receptor in all melanoma metastases, is constitutively active and inhibits apoptosis, indicating an important role for GPR18 in tumor cell survival. PMID: 20880198
    5. N-arachidonylglycine is a natural ligand for GPR18 PMID: 16844083

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed in midpiece of spermatozoon (at protein level). Most abundant in testis and spleen. Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells.
  • 數據庫鏈接：

    HGNC: 4472

    OMIM: 602042

    KEGG: hsa:2841

    STRING: 9606.ENSP00000343428

    UniGene: Hs.741589



主站蜘蛛池模板： 亚洲熟妇丰满大屁股熟妇| yy111111少妇无码理论片| 娇小萝被两个黑人用半米长| 亚洲色大成网站在线| 青青草国产精品欧美成人| 18禁止午夜福利体验区| 一本大道东京热无码| 免费又黄又爽又色的视频| 日韩人妻无码一区二区三区久久99| 极品无码av国模在线观看 | 亚洲一本一道一区二区三区| 67194熟妇在线观看线路1 | 国产在线观看www污污污| 成人午夜精品无码一区二区三区| 欧美成a人片在线观看久| 2021无码最新国产在线观看| 亚洲成av人片在一线观看| 午夜dj高清免费观看视频| 久久亚洲欧美国产精品| 综合久久给合久久狠狠狠97色 | 久久99久久99精品中文字幕| 久久毛片免费看一区二区三区 | 无码国内精品久久综合88| 东北少妇不带套对白| 99热门精品一区二区三区无码 | 国产乱码一区二区三区爽爽爽| 精品无人码麻豆乱码1区2区 | 亚洲色爱图小说专区| 久久精品国产欧美日韩| 国产精品久久久久久久9999| 亚洲国产成人精品无码区在线软件| 日韩99在线 | 中文| 激情内射日本一区二区三区| 亚洲真人无码永久在线| 国产成人高清精品免费| 伊人色综合九久久天天蜜桃| 国产成人午夜精华液| 免费的很黄很污的视频| 少妇夜夜春夜夜爽试看视频| 饥渴少妇高潮视频大全| 亚洲欧美日韩久久精品第一区|