在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15), partial

Recombinant Human N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15), partial

  • 中文名稱：
    人NAA15重組蛋白
  • 貨號：
    CSB-YP863143HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人NAA15重組蛋白
  • 貨號：
    CSB-EP863143HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人NAA15重組蛋白
  • 貨號：
    CSB-EP863143HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人NAA15重組蛋白
  • 貨號：
    CSB-BP863143HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人NAA15重組蛋白
  • 貨號：
    CSB-MP863143HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    NAA15
  • Uniprot No.：
  • 別名：
    5730450D16Rik; 6330400I15; ASTBDN; GA19 ; Gastric cancer antigen Ga19; MGC29428; mNAT1; N alpha acetyltransferase 15, NatA auxiliary subunit; N terminal acetyltransferase; N(alpha) acetyltransferase 15, NatA auxiliary subunit ; N-alpha-acetyltransferase 15; N-terminal acetyltransferase; Naa15; NAA15_HUMAN; NatA auxiliary subunit; NATH ; NMDA receptor regulated 1; NMDA receptor regulated protein 1; NMDA receptor-regulated protein 1; Protein tubedown 1 ; Protein tubedown-1; Tbdn 1; Tbdn100; Transcriptional coactivator tubedown 100; tubedown-1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Auxillary subunit of N-terminal acetyltransferase complexes which display alpha (N-terminal) acetyltransferase (NAT) activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter.
  • 基因功能參考文獻：
    1. individuals with copy-number variant (CNV) deletions involving NAA15 and surrounding genes can present with mild intellectual disability, mild dysmorphic features, motor delays, and decreased growth. PMID: 29656860
    2. In combination with acetylation assays, the HypK N-terminal region is identified as a negative regulator of the NatA acetylation activity PMID: 28585574
    3. Authors highlight NAA15 as a novel candidate ID gene based on the vital role of NAA15 in the generation and differentiation of neurons in neonatal brain. PMID: 28990276
    4. Human Naa15 (NATH) and Naa10 (ARD1) form a stable NatA complex which associates with ribosomes and performs co-translational N-terminal acetylation; Naa15 (NATH) and Naa10 (ARD1) are cleaved during apoptosis resulting in decreased acetyltransferase activity PMID: 15496142
    5. Development of the first N-terminal acetyltransferase (NAT) inhibitors, including inhibitors to the NatA complex composed of Naa10 (ARD1) and Naa15 (NATH). PMID: 23557624
    6. Protein N-terminal acetyltransferases (NATs), including the NatA complex composed of Naa10 (ARD1) and Naa15 (NATH), act as N-terminal propionyltransferases. PMID: 23043182
    7. Data indicate that the physical interaction between HYPK and NatA Naa10/15 seems to be of functional importance both for huntingtin aggregation and for N-terminal acetylation. PMID: 20154145
    8. NATH, a novel gene overexpressed in papillary thyroid carcinomas. PMID: 12140756
    9. description of the human homologue of Nat1p, NATH (NAT human), as the binding partner of the hARD1 (human ARD1) protein PMID: 15496142
    10. levels of endogenous NATH and hARD1 proteins in thyroid papillary carcinoma patients; results suggest that NATH positively affects the level of hARD1 protein both in vivo and in cell cultures PMID: 16279846
    11. Loss of retinal endothelial Tbdn-1 expression may be a contributing factor in retinal blood vessel proliferation in retinopathy of prematurity. PMID: 16518308
    12. Essential role in cell survival through protein N-alpha-acetylation. PMID: 16518407
    13. NATH complexes with hARD1 in a ribosomal associated protein-N-acetyltransferase complex. PMID: 15496142

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Mainly cytoplasmic, nuclear in some cases. Present in the free cytosolic and cytoskeleton-bound polysomes, but not in the membrane-bound polysomes.
  • 組織特異性：
    Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, u
  • 數據庫鏈接：

    HGNC: 30782

    OMIM: 608000

    KEGG: hsa:80155

    STRING: 9606.ENSP00000296543

    UniGene: Hs.745047



主站蜘蛛池模板： 久久久性色精品国产免费观看 | 国产精品va无码二区| 国产真人做爰视频免费| 成年轻人电影免费无码| 久久狼人大香伊蕉国产| 国产电影一区二区三区| 射死你天天日| 人妻妺妺窝人体色www聚色窝| 午夜国人精品av免费看| 日韩在线 | 中文| 青青青国产精品一区二区| 国产98色在线 | 国产| 国产毛片精品av一区二区| 99久久精品国产一区二区 | 国产精品久久久久高潮| 亚洲一区精品无码| 久久亚洲人成综合网| 久久国产超碰女女av| 国产精品污www一区二区三区| aaa少妇高潮大片免费看| 亚洲精品综合在线影院| 国产曰批免费视频播放免费| 欧美怡红院免费全部视频| 中文字幕人成乱码熟女app| 亚洲中文字幕无码人在线| 久久精品道一区二区三区| 亚洲精品国产精品乱码不卡√| 中文字幕爆乳julia女教师| 国产精品久久久久久久久久久久午衣片| 国精品人妻无码一区免费视频电影 | 人与嘼av免费| 亚洲精品成人片在线播放| 精品久久一区二区乱码| 成在人线无码aⅴ免费视频| 亚洲国产区男人本色| 国语国产精精品国产国语清晰对话 | 性男女做视频观看网站| 久久久久亚洲国产av麻豆| 国产精自产拍久久久久久蜜 | 久久精品成人免费国产片小草| 人妻体验按摩到忍不住哀求继续 |