在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Mitotic spindle-associated MMXD complex subunit MIP18 (FAM96B)

  • 中文名稱:
    人FAM96B重組蛋白
  • 貨號:
    CSB-EP897544HU
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    FAM96B
  • Uniprot No.:
  • 別名:
    CGI 128; FAM96B; Family with sequence similarity 96; member B; HSPC118; Hypothetical protein LOC51647; MIP18; MIP18_HUMAN; Mitotic spindle-associated MMXD complex subunit MIP18; MSS19-interacting protein of 18 kDa; Protein FAM96B
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    44.5kDa
  • 表達區(qū)域:
    1-163aa
  • 氨基酸序列
    VGGGGVGGGLLENANPLIYQRSGERPVTAGEEDEQVPDSIDAREIFDLIRSINDPEHPLTLEELNVVEQVRVQVSDPESTVAVAFTPTIPHCSMATLIGLSIKVKLLRSLPQRFKMDVHITPGTHASEHAVNKQLADKERVAAALENTHLLEVVNQCLSARS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Together with MMS19, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis.
  • 基因功能參考文獻:
    1. Data suggest that CIA2B and MMS19 physically interact with C-terminus of viperin/RSAD2; CIAO1 appears to function as primary viperin-interacting protein; CIA2A binds to N-terminus of viperin in CIAO1-, CIA2B-, and MMS19-independent fashion. (CIA2B = metallochaperone CIA2B/FAM96B; MMS19 = transcription factor MMS19; CIAO1 = cytosolic iron-sulfur assembly component 1; CIA2A = metallochaperone CIA2A/Fam96a) PMID: 28615450
    2. CIA2B-CIA1-MMS19 and CIA2A-CIA1 assist different branches of Fe/S protein assembly and intimately link this process to cellular iron regulation via IRP1 Fe/S cluster maturation and IRP2 stabilization. PMID: 23891004
    3. Co-localization experiments by fluorescent confocal microscopy revealed that FAM96B colocalized with prelamin A in HEK-293 cells. PMID: 24041693
    4. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly. PMID: 23150669
    5. these findings suggest that FAM96B acts as a regulator of E2-2 through the control of its protein expression. PMID: 21722264

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody.
  • 蛋白家族:
    MIP18 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24261

    OMIM: 614778

    KEGG: hsa:51647

    STRING: 9606.ENSP00000387471

    UniGene: Hs.9825



主站蜘蛛池模板: 欧美亚洲色欲色一欲www| 性色a∨精品高清在线观看| 国产精品视频一区二区亚瑟| 国精产品48x国精产品| 中文字幕一区二区三区四区五区 | 亚洲国产精品隔壁老王 | 荡女精品导航| 午夜婷婷精品午夜无码a片影院| 亚洲 卡通 欧美 制服 中文| 无码爆乳护士让我爽| av在线播放无码线| 亚洲 丝袜 制服 欧美 另类| www一区二区乱码www| 色婷婷综合缴情综免费观看| 豆国产96在线 | 亚洲| 秋霞av在线露丝片av无码| 成人免费乱码大片a毛片| 最新高清无码专区| 国产精品成人久久久久久久| 亚洲日韩欧美国产另类综合| 18禁又污又黄又爽的网站不卡| 玩弄japan白嫩少妇hd小说| 自慰系列无码专区| 老汉老妇姓交视频| 中文字幕av无码一区二区三区电影| 亚洲午夜福利av一区二区无码| 无码h黄动漫在线播放网站| 欧美老妇乱辈通奷| 国产精品久久久久9999爆乳| 天天做天天躁天天躁| 男女啪啪抽搐高潮动态图| 中国熟妇人妻xxxxx| 精品一区二区不卡无码av| 亚洲成a×人片在线观看| 国产制服丝袜欧美在线观看| 性生交大片免费看女人按摩 | 丰满护士巨好爽好大乳| 97国产一区二区三区四区久久| 欧亚乱熟女一区二区在线| 国产亚洲精品久久久久久打不开| 亚洲 欧美 影音先锋|