Recombinant Human Mitogen-activated protein kinase kinase kinase 6 (MAP3K6), partial

中文名稱：

人MAP3K6重組蛋白
貨號：

CSB-YP013428HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人MAP3K6重組蛋白
貨號：

CSB-EP013428HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人MAP3K6重組蛋白
貨號：

CSB-EP013428HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MAP3K6重組蛋白
貨號：

CSB-BP013428HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人MAP3K6重組蛋白
貨號：

CSB-MP013428HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

MAP3K6
Uniprot No.：

O95382
別名：

Apoptosis signal regulating kinase 2; Apoptosis signal-regulating kinase 2; ASK2; EC 2.7.11.25; M3K6_HUMAN; MAP3K6; MAPKKK6; MEKK6; MGC125653; MGC20114; Mitogen-activated protein kinase kinase kinase 6
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
基因功能參考文獻(xiàn)：
1. Data show that the MAPKKK6 ASK2, a modulator of MAPKKK5 ASK1 signaling, was essential for ASK1-dependent apoptosis, but not for inducing interferon-beta (IFNB) expression. PMID: 26243192
2. MAP3K6 acts as a tumor suppressor, and studies showing the presence of somatic mutations in MAP3K6 in non-hereditary gastric cancers and gastric cancer cell lines, point towards MAP3K6 variants as a predisposing factor for familial gastric cancer PMID: 25340522
3. Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1. PMID: 17210579
蛋白家族：

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
數(shù)據(jù)庫鏈接：

HGNC: 6858

OMIM: 604468

KEGG: hsa:9064

STRING: 9606.ENSP00000350195

UniGene: Hs.194694