在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Mitochondrial uncoupling protein 4 (SLC25A27), partial

  • 中文名稱:
    人SLC25A27重組蛋白
  • 貨號:
    CSB-YP021496HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SLC25A27重組蛋白
  • 貨號:
    CSB-EP021496HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SLC25A27重組蛋白
  • 貨號:
    CSB-EP021496HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SLC25A27重組蛋白
  • 貨號:
    CSB-BP021496HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SLC25A27重組蛋白
  • 貨號:
    CSB-MP021496HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SLC25A27
  • Uniprot No.:
  • 別名:
    SLC25A27; UCP4; UNQ772/PRO1566; Mitochondrial uncoupling protein 4; UCP 4; Solute carrier family 25 member 27
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. May play a role in thermoregulatory heat production and metabolism in brain.
  • 基因功能參考文獻:
    1. This study found that the variability of UCP4 does affect the individual susceptibility to Late-Onset Alzheimer's Disease. PMID: 26923023
    2. UCP4 mRNA of cartilage tissues was decreased in osteoarthritis patients, which was negatively correlated with synovial fluid (SF) leptin concentration. PMID: 26934480
    3. UCP4 is a target effector gene of the NF-kappaB c-Rel prosurvival pathway to mitigate the effects of oxidative stress. PMID: 22580300
    4. Neuronal UCP4 exhibits transmembrane chloride transport activity. PMID: 22524567
    5. Findings show how UCP4 overexpression increases ATP synthesis by specifically interacting with Complex II. PMID: 22427795
    6. UCP4 expression correlated with lymph node metastases, positive estrogen/progesterone receptor expression, and positivity for p53 and Ki-67 in breast carcinomas. PMID: 21621926
    7. A homozygous genetic variant of mitochondrial uncoupling protein 4 affects the occurrence of leukoaraiosis.( PMID: 20545631
    8. the association found between the ultra-resistant schizophrenia group and the UCP4 haplotype is noteworthy as it may influence treatment outcome in schizophrenia. PMID: 21332312
    9. has a significant role in NF-kappaB-mediated prosurvival signaling and cell protection against neurotoxins PMID: 20385226
    10. Results suggest that mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress. PMID: 16775390
    11. The stabilization of Ca(2+) homeostasis and preservation of mitochondrial function by UCP4 was correlated with reduced mitochondrial reactive oxygen species generation and oxidative stress. PMID: 17035241
    12. overexpression increases neural cell survival by inducing oxidative phosphorylation, preserving ATP synthesis and mitochondrial membrane potential, and reducing oxidative stress. PMID: 19150400
    13. Data describe how variants of mitochondrial uncoupling protein 4 (mUCP4) may contibute to development of multiple sclerosis, since mUCP4 is presumed to be of importance in regulation of the mitochondrial membrane potential and cellular energy metabolism. PMID: 19536655

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Mitochondrial carrier (TC 2.A.29) family
  • 組織特異性:
    Found in adult and fetal brain. Present in most of the brain tissues, with low levels in spinal chord, corpus callosum and substantia nigra.
  • 數據庫鏈接:

    HGNC: 21065

    OMIM: 613725

    KEGG: hsa:9481

    STRING: 9606.ENSP00000360398

    UniGene: Hs.40510



主站蜘蛛池模板: 一区二区在线欧美日韩中文| 最新av偷拍av偷窥av网站| 国内精品九九久久精品| 精品久久人人妻人人做精品| 揉捏奶头高潮呻吟视频| 国产精品午夜福利不卡120| 亚洲mv国产mv在线mv综合试看| 国产精品毛片在线完整版| 成人网站国产在线视频内射视频| 久久久久久久久888| 久久久久99精品国产片| 8天堂资源在线| 亚洲另类无码专区丝袜| 四虎永久在线精品884aa| 精品人妻潮喷久久久又裸又黄| 真实国产乱啪福利露脸| 成人动漫在线观看| 亚洲vav在线男人的天堂| 无码人妻专区免费视频| 精品偷拍一区二区三区在线看| av老司机亚洲精品天堂| 国产无线乱码一区二三区| 欧洲vat一区二区三区| 蜜臀av片在线观看| 粉色午夜视频| 欧美性插b在线视频网站| 国产做爰xxxⅹ高潮视频12p| 亚洲图欧洲图自拍另类高清| 国色天香在线视频www| 中文字幕人妻无码视频| 熟妇熟女乱妇乱女网站| 中文字幕丰满乱子无码视频| 人人添人人澡人人澡人人人人| 成人欧美一区二区三区的电影 | 国产精品久久久久久久久软件| 精品视频国产狼友视频| 天堂最新版在线www| 中文字幕乱码人妻综合二区三区| 久久午夜无码鲁丝片秋霞| 无码中出人妻中文字幕av| 国产又爽又黄又无遮挡的激情视频|