在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Mitochondrial fission factor (MFF), partial

  • 中文名稱:
    人MFF重組蛋白
  • 貨號(hào):
    CSB-YP013751HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    人MFF重組蛋白
  • 貨號(hào):
    CSB-EP013751HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MFF重組蛋白
  • 貨號(hào):
    CSB-BP013751HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MFF重組蛋白
  • 貨號(hào):
    CSB-MP013751HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MFF
  • Uniprot No.:
  • 別名:
    C2orf33 ; Chromosome 2 open reading frame 33; DKFZp666J168; GL004 ; Mff; MFF_HUMAN; MGC110913; Mitochondrial fission factor; OTTHUMP00000164235
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.
  • 基因功能參考文獻(xiàn):
    1. Data show that increasing dynamin-related protein 1 (Drp1) SUMOylation by knocking down SUMO1-sentrin-SMT3 specific protease 3 (SENP3) reduces both Drp1 binding to mitochondrial fission factor protein (Mff) and stress-induced cytochrome c release. PMID: 28262828
    2. expressions of TIA-1 and MFF were augmented in the cancerous liver tissues compared to the corresponding non-tumor tissues at mRNA and protein level, while the levels of miR-200a-3p and miR-27a/b were relatively lower in the cancerous liver tissues PMID: 29496454
    3. We suggest that, even if laboratory findings are not indicative of mitochondrial or peroxisomal dysfunction, the co-occurrence of optic and/or peripheral neuropathy with seizures warrants genetic testing for MFF mutations PMID: 26783368
    4. membrane-anchored Mff differentially regulates various Drp1 isoforms. PMID: 26578513
    5. Data show that expression of MFF protein, miR-593-5p and BRCA1 protein correlates with cisplatin sensitivity and survival of tongue squamous cell carcinoma (TSCC). PMID: 25912308
    6. loss of Mff results in failure of Parkin translocation and final clearance of damaged mitochondria PMID: 26008206
    7. Mitochondrial fission factor (MFF) mRNA is a direct target of miR-27, whose ectopic expression decreases MFF expression through binding to its 3'-untranslated region. PMID: 25431021
    8. TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression. PMID: 23284813
    9. PEX11 proteins attract both Mff and human Fis1 (hFis1) to their site of action. PMID: 22595523
    10. MFF over-expression results in extensive mitochondrial fragmentation, driving mitochondrial dysfunction. MFF fibroblasts undergo oxidative stress, with increased ROS production, and the onset of autophagy and mitophagy. PMID: 22878233
    11. MFF gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
    12. Mff is a novel component of a conserved membrane fission pathway used for constitutive and induced fission of mitochondria and peroxisomes. PMID: 18353969

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Encephalopathy due to defective mitochondrial and peroxisomal fission 2 (EMPF2)
  • 亞細(xì)胞定位:
    Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
  • 蛋白家族:
    Tango11 family
  • 組織特異性:
    Highly expressed in heart, kidney, liver, brain, muscle, and stomach.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 24858

    OMIM: 614785

    KEGG: hsa:56947

    STRING: 9606.ENSP00000302037

    UniGene: Hs.471528



主站蜘蛛池模板: 国产精品白丝喷水在线观看| 精品乱码一区二区三四五区| 午夜亚洲福利在线老司机| 精品国产天线2019| 大肉大捧一进一出视频| 国产高清亚洲精品视bt天堂频| 中文字幕+乱码+中文乱码www| 一边做一边喷17p亚洲乱妇50p| 曰批视频免费30分钟成人| 成人小说亚洲一区二区三区| 久久欧美国产伦子伦精品| 成 人 亚洲 综合天堂| 2021国产精品成人免费视频| 女人被强╳到高潮喷水在线观看| 丰满少妇被猛烈进入高清播放| 国产激情大臿免费视频| 国产亚洲中文字幕在线制服| 深夜福利小视频在线观看| 鲁鲁鲁爽爽爽在线视频观看| 人妻无码中文字幕| 美女黄频视频大全免费的国内| 亚洲国产成人无码电影| 熟妇人妻系列aⅴ无码专区友真希| 免费人妻精品一区二区三区| 综合无码成人aⅴ视频在线观看| 东京热无码国产精品| 国产成人av一区二区三区| 久久www香蕉免费人成| 久久精品国产99久久久小说| 男女边吃奶边做边爱视频| 男人j进入女人j内部免费网站| 亚洲精品久久久久中文第一幕| 国产精品人妻系列21p| 国产日韩欧美不卡在线二区| 国产小呦泬泬99精品| 日韩人妻精品一区二区三区视频| 欧美丰满大乳高跟鞋| 国内精品久久久久久不卡影院| 少妇把腿扒开让我爽爽视频| 免费无码成人av在线播| 国产 制服丝袜 动漫在线|