在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MFF Antibody

MFF Antibody

  • 中文名稱：
    MFF兔多克隆抗體
  • 貨號(hào)：
    CSB-PA834434
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA834434(MFF Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA834434(MFF Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MFF
  • 別名：
    C2orf33 antibody; Chromosome 2 open reading frame 33 antibody; DKFZp666J168 antibody; GL004 antibody; Mff antibody; MFF_HUMAN antibody; MGC110913 antibody; Mitochondrial fission factor antibody; OTTHUMP00000164235 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human MFF
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.
  • 基因功能參考文獻(xiàn)：
    1. Data show that increasing dynamin-related protein 1 (Drp1) SUMOylation by knocking down SUMO1-sentrin-SMT3 specific protease 3 (SENP3) reduces both Drp1 binding to mitochondrial fission factor protein (Mff) and stress-induced cytochrome c release. PMID: 28262828
    2. expressions of TIA-1 and MFF were augmented in the cancerous liver tissues compared to the corresponding non-tumor tissues at mRNA and protein level, while the levels of miR-200a-3p and miR-27a/b were relatively lower in the cancerous liver tissues PMID: 29496454
    3. We suggest that, even if laboratory findings are not indicative of mitochondrial or peroxisomal dysfunction, the co-occurrence of optic and/or peripheral neuropathy with seizures warrants genetic testing for MFF mutations PMID: 26783368
    4. membrane-anchored Mff differentially regulates various Drp1 isoforms. PMID: 26578513
    5. Data show that expression of MFF protein, miR-593-5p and BRCA1 protein correlates with cisplatin sensitivity and survival of tongue squamous cell carcinoma (TSCC). PMID: 25912308
    6. loss of Mff results in failure of Parkin translocation and final clearance of damaged mitochondria PMID: 26008206
    7. Mitochondrial fission factor (MFF) mRNA is a direct target of miR-27, whose ectopic expression decreases MFF expression through binding to its 3'-untranslated region. PMID: 25431021
    8. TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression. PMID: 23284813
    9. PEX11 proteins attract both Mff and human Fis1 (hFis1) to their site of action. PMID: 22595523
    10. MFF over-expression results in extensive mitochondrial fragmentation, driving mitochondrial dysfunction. MFF fibroblasts undergo oxidative stress, with increased ROS production, and the onset of autophagy and mitophagy. PMID: 22878233
    11. MFF gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma. PMID: 21509594
    12. Mff is a novel component of a conserved membrane fission pathway used for constitutive and induced fission of mitochondria and peroxisomes. PMID: 18353969

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Encephalopathy due to defective mitochondrial and peroxisomal fission 2 (EMPF2)
  • 亞細(xì)胞定位：
    Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
  • 蛋白家族：
    Tango11 family
  • 組織特異性：
    Highly expressed in heart, kidney, liver, brain, muscle, and stomach.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 24858

    OMIM: 614785

    KEGG: hsa:56947

    STRING: 9606.ENSP00000302037

    UniGene: Hs.471528



主站蜘蛛池模板： 中文字幕久久综合伊人| 亚洲精品一区二区三区影院| 国产精品熟妇一区二区三区四区| 亚洲精品喷潮一区二区三区| 国产高清在线精品一本大道| 亚洲色偷偷偷网站色偷一区| 内射白嫩少妇超碰| 欧美男生射精高潮视频网站| 国产亚洲日本精品成人专区| 中美日韩毛片免费播放| 久热国产精品视频一区二区三区 | 日本高清二区视频久二区| 午夜羞羞影院男女爽爽爽| 大学生高潮无套内谢视频| 亚洲精品欧美综合四区| 免费人成视频在线播放视频| 国产xxxx99真实实拍| 久久久久久毛片免费播放| 办公丝袜av一区二区三区| 99久久九九社区精品| 国产精品毛片大码女人| 成年女人a毛片免费视频| 麻豆国产成人av在线播放| 天天爽夜夜爽视频精品| 亚洲精品中文字幕乱码三区| 国产三区在线成人av| 精品国内自产拍在线观看| 亚洲精品久久久久久中文| 国产午夜无码视频在线观看| 亚洲香蕉视频天天爽| 先锋影音人妻啪啪va资源网站| 久久九九有精品国产尤物| 国产精品户外野外| 久久视频这里只精品| 免费看国产zzzwww色| 第九色区av天堂| 久久www成人_看片免费不卡| 精品久久久久久亚洲中文字幕| 五月婷婷久久草丁香| 久热国产vs视频在线观看| 日韩午夜理论免费tv影院|