在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Metallothionein-1X (MT1X), partial

In Stock
  • 中文名稱:
    人MT1X重組蛋白
  • 貨號:
    CSB-EP015119HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    MT1X
  • Uniprot No.:
  • 別名:
    MT1X; Metallothionein-1X; MT-1X; Metallothionein-IX; MT-IX
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    32.9kDa
  • 表達區域:
    1-59aa
  • 氨基酸序列
    MDPNCSCSPVGSCACAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGTSDKCSC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產品描述:

    The DNA coding sequence translated into the human MT1X protein sequence (1-59aa) was fused with the N-terminal GST tag sequence to form the recombinant DNA, which was inserted into an expression vector. The reconstructed expression vector was transformed into the E.coli for follow-up expression. The product underwent purification to obtain the recombinant human MT1X protein with N-terminal GST tag. The SDS-PAGE analysis determined its purity higher than 90%. After electrophoresis, a 32 kDa protein band was observed on the gel.

    MT1X is a gene encoding a protein named Metallothionein-1X (abbreviated MT1X) in human and belongs to Metallothionein superfamily. Metallothionein (MT) is a kind of metal-binding protein rich in cysteine and ubiquitous. It has important significance for maintaining the metabolic balance of some essential metals in the body, resisting toxic metal toxicity, and clearing free radicals. Human MT genes include 10 functional genes: MT1A, MT1B, MT1E, MT1F, MT1G, MT1H, MT1X, MT2A, MT3 and MT4. A study has shown that cells with high expression of MT1X have strong anti-apoptotic properties, which can induce cisplatin resistance in cells.

  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling.
  • 基因功能參考文獻:
    1. Data show that in the MCF-7 breast cancer cell line, only MT1X metallothioneins (MTs) positively correlated with vascular endothelial growth factor C (VEGFC). PMID: 27107086
    2. MT1XT20 Single Quasi-Monomorphic Mononucleotide Marker showing Microsatellite Instability is associated with Persian Lynch Syndrome PMID: 27797228
    3. These findings suggest that functional interactions between FHL3 and MT-1X may provide some clues to the mechanisms of FHL3-regulated cell proliferation. PMID: 24690879
    4. Results show variation in MTX1 is implicated in disordered gambling PMID: 22780124
    5. siRNA-mediated knockdown of TCRP1 and MT1X was found to sensitize cells to cisplatin, leading to increased apoptosis and inhibition of cell proliferation PMID: 23251525
    6. Our results suggest that MT1XT20 represents a sensitive and specific marker for MSI testing and could be included in a complete set of MSI markers for the confident identification of familial or sporadic dMMR patients in colorectal cancers. PMID: 22108904
    7. It plays a role in the detoxification of heavy metals and reactive oxygen species. (review) PMID: 19881214

    顯示更多

    收起更多

  • 蛋白家族:
    Metallothionein superfamily, Type 1 family
  • 數據庫鏈接:

    HGNC: 7405

    OMIM: 156359

    KEGG: hsa:4501

    STRING: 9606.ENSP00000377995

    UniGene: Hs.374950



主站蜘蛛池模板: 在线天堂资源www在线污| 三叶草欧洲码在线| 无遮挡又爽又刺激的视频| 色婷婷我要去我去也| 色婷婷亚洲精品综合影院| 国产九九九九九九九a片| 奇米影视第四色首页| 久久亚洲美女精品国产精品| 不卡无码人妻一区三区音频| 成人午夜特黄aaaaa片男男| 中国孕妇变态孕交xxxx| 国产精品乱码在线观看| 老司机免费的精品视频| 两性色午夜视频免费无码| 男男啪啪激烈高潮cc漫画免费 | 波多野结衣的av一区二区三区| 国产又色又爽又黄刺激的视频| 国产69精品久久久久孕妇| 日日夜夜撸啊撸| 成人区人妻精品一区二区不卡视频| 国产精品午夜福利不卡| 国产精品992tv在线观看| 国产午夜福利片在线观看| 九九视频在线观看视频6| 99精品丰满人妻无码a片| 久久久久国产精品人妻aⅴ果冻 | 狠狠色色综合网站| 国产乱人伦在线播放| 看黄a大片爽爽影院免费无码| 秋霞午夜一区二区三区黄瓜视频| 免费无码精品黄av电影| 欧美性xxxxx极品少妇| 欧美精品黑人粗大破除| 欧美老熟妇乱子| 99精品视频在线观看| 99久热re在线精品视频| 丰满多毛少妇做爰视频爽爽和 | 免费无码av一区二区| 欧美成人aaaa免费全部观看| 国产又黄又爽又色的免费视频| 久久久久久久久久久国产|