在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lysine-specific demethylase 3B (KDM3B), partial

In Stock
  • 中文名稱:
    人KDM3B重組蛋白
  • 貨號:
    CSB-EP759174HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    KDM3B
  • Uniprot No.:
  • 別名:
    5qNCA; C5orf7; JHDM2B; JmjC domain containing histone demethylation protein 2B; JmjC domain-containing histone demethylation protein 2B; jmjd1b; Jumonji domain containing 1B; Jumonji domain containing protein 1B; Jumonji domain-containing protein 1B; KDM3B; KDM3B_HUMAN; KIAA1082; Lysine (K) specific demethylase 3B ; Lysine-specific demethylase 3B; NET22; Nuclear protein 5qNCA
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    45.6kDa
  • 表達區域:
    1498-1721aa
  • 氨基酸序列
    MPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
  • 基因功能參考文獻:
    1. we found that KDM3B exhibits potential tumor-suppressive activity and transcriptionally modulates HOXA1 expression via RARE in AML. PMID: 28540746
    2. H3K9 demethylase KDM3B represses transcription of the angiogenesis regulatory gene, ANGPT1. PMID: 25413303
    3. High expression of KDM3B and KDM5A is associated with a better prognosis (no recurrence after mastectomy p=0.005 and response to docetaxel p=0.005)in breast cancer patients. PMID: 23266085
    4. evidence that the H3K9-me1/2 demethylase KDM3B might play a role in leukemogenesis via activation of lmo2 through interdependent actions with the histone acetyltransferase complex containing CBP PMID: 22615488
    5. A novel nuclear protein, 5qNCA is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31. PMID: 11687974

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    JHDM2 histone demethylase family
  • 組織特異性:
    Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.
  • 數據庫鏈接:

    HGNC: 1337

    OMIM: 609373

    KEGG: hsa:51780

    STRING: 9606.ENSP00000326563

    UniGene: Hs.483486



主站蜘蛛池模板: 人妻丰满熟妇av无码区hd| 无码一区二区三区视频| 手机看片久久国产免费| 国产精品久久久久久超碰| 欧美性大战久久久久久| 亚洲va久久久噜噜噜久久4399| 亚洲精品尤物av在线观看不卡| 97国语精品自产拍在线观看| 公与淑婷厨房猛烈进出视频免费| 国内精品视频一区二区三区 | 久久综合亚洲色一区二区三区| 亚洲人成精品久久久久| 伊人久久大香线蕉avapp下载| 午夜爽爽爽男女污污污网站| 免费无码又爽又刺激成人| 免费观看又色又爽又湿的视频| 成人午夜福利视频| 中文字幕无码av波多野吉衣 | 无码人妻品一区二区三区精99| 欧美性狂猛xxxxx深喉| 先锋影音av最新资源网| 国产无套精品一区二区三区| 久久亚洲精品成人av无码网站| 色婷婷我要去我去也| av性色在线乱叫| 青青久在线视频免费观看| 99久久国语露脸精品国产| 久久精品人人槡人妻人人玩av | 五十路熟妇强烈无码| 人妻少妇精品一区二区三区| 亚洲欧美日韩精品久久亚洲区| 亚洲这里只有久热精品伊人| 成 人 社区在线视频| 久久99国产精品久久| 国产精品自在欧美一区| 女乱高潮久久久久久爽爽| 国产内射xxxxx在线| 激情综合丁香五月| 中文字幕一区二区人妻| 亚洲综合熟女久久久40p| 国产jk白丝在线观看免费|