在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lymphotoxin-beta (LTB TNFC TNFSF3)

  • 中文名稱:
  • 貨號:
    CSB-YP013220HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP013220HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-EP013220HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-BP013220HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
  • 貨號:
    CSB-MP013220HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TNFC
  • Uniprot No.:
  • 別名:
    Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3; LTB TNFC TNFSF3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
  • 基因功能參考文獻:
    1. Combination of an EGFR tyrosine kinase inhibitor and a NF-kappaB inhibitor effectively suppressed cetuximab-resistant HNSCC and interfering with the EGFR-LTbeta interaction reverses resistance. PMID: 28196873
    2. TNF is able to upregulate LT-beta expression in hepatic cells at the transcriptional level by the binding of NF-kappaB p50/p65 heterodimers and Ets1 to their respective sites in the LT-beta promoter. PMID: 22742857
    3. The multifaceted character of lymphotoxin beta may be involved in inflammatory myopathies and muscular dystrophies. PMID: 22652080
    4. Data show differential expression of interferon-gamma, TNFSF3, TNFSF10, TNFSF12 and PDGFbeta in CD8+, CD14+ and CD4+ cells. PMID: 21211989
    5. Findings provide evidence of additional complexity in the transcriptional regulation of LTB with implications for coordinate expression of genes in this important genomic locus. PMID: 21248773
    6. Heterotypic interaction between LTbeta-producing lymphocytes and responding fibroblast-like synoviocytes contributes to establishment of complex lymphoid microstructures. May be one element in susceptibility of synovial membrane to lymphoid organogenesis. PMID: 15248211
    7. The identification of IL-6 and IL-1beta as activators of LT-beta supports their involvement in LT-beta signaling in liver regeneration associated with chronic liver damage. PMID: 15910501
    8. Lymphotoxin (LT) beta receptor ligands LTalpha1 and -beta2 activate both the classical and noncanonical NF-kappa B pathways in human vascular endothelial cells and dermal microvascular endothelial cells in vitro. PMID: 18292573
    9. LT-Beta may play a role in rheumatoid arthritis disease pathogenesis by contributing to a more intense inflammatory reaction in the synovium PMID: 18379788
    10. blocking the lymphotoxin-beta receptor pathway results in ablation of the lymphoid organization in the NOD salivary glands and thus an improvement in salivary gland function. PMID: 19222863

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Tumor necrosis factor family
  • 組織特異性:
    Spleen and thymus.
  • 數據庫鏈接:

    HGNC: 6711

    OMIM: 600978

    KEGG: hsa:4050

    STRING: 9606.ENSP00000410481

    UniGene: Hs.376208



主站蜘蛛池模板: 男男又爽又黄又无遮挡网站| 亚洲精品99久久久久中文字幕| 影音先锋人妻啪啪av资源网站| 无翼乌工口肉肉无遮挡无码18| 国产亚洲精品无码不卡| 日本一区二区三区免费播放视频站 | 亚洲精品美女久久777777| 色悠久久久久久久综合网| 18禁成人网站免费观看| 九九综合九色综合网站| 亚洲高清成人av电影网站 | 欧美丰满美乳xxⅹ高潮www | 中文字幕丝袜第1页| 天天做天天爱夜夜夜爽毛片| 大香伊蕉国产av| 国产精品成人永久在线四虎| 日韩69永久免费视频| 亚洲欧洲日产国码无码| 美女扒开大腿让男人桶| 小嫩妇好紧好爽再快视频| 最新国产aⅴ精品无码| 免费永久在线观看黄网站| 国产熟睡乱子伦午夜视频麻豆| 久久人人爽人人爽人人片av不| 精品国产乱码久久久久夜深人妻| 碰超免费人妻中文字幕| 无码精品人妻一区二区三区av| 97久久精品人人做人人爽| 亚洲日本中文字幕天天更新| 欧美精品成人v高清视频| 爆乳喷奶水无码正在播放| 久久久久成人精品| 人与动人物xxxx毛片人与狍 | 国产毛多水多高潮高清| 成年轻人电影免费无码| 无码一区二区三区av在线播放| 国产欧美一区二区三区在线看| 久久www免费人成_看片| 国产福利一区二区麻豆| 亚洲午夜成人片| 精品黑人一区二区三区|