在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Lipocalin-1 (LCN1)

In Stock
  • 中文名稱:
    Recombinant Human Lipocalin-1 (LCN1)
  • 貨號(hào):
    CSB-YP012810HU
  • 規(guī)格:
    ¥1656
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    LCN1
  • Uniprot No.:
  • 別名:
    Tear lipocalin;Tlc;Tear prealbumin;TP;von Ebner gland protein;VEG protein
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    19.2 kDa
  • 表達(dá)區(qū)域:
    19-176aa
  • 氨基酸序列
    HHLLASDEEIQDVSGTWYLKAMTVDREFPEMNLESVTPMTLTTLEGGNLEAKVTMLISGRCQEVKAVLEKTDEPGKYTADGGKHVAYIIRSHVKDHYIFYCEGELHGKPVRGVKLVGRDPKNNLEALEDFEKAAGARGLSTESILIPRQSETCSPGSD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    C-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
  • 基因功能參考文獻(xiàn):
    1. At the relatively small concentrations in tears, all ceramides were complexed to tear lipocalin. PMID: 29331331
    2. Human neutrophil lipocalin (HNL) concentrations in serum or whole blood activated by formyl-methionine-leucine-phenylalanine (fMLP) were shown to distinguish acute infections of bacterial or viral cause with high accuracy. PMID: 26135974
    3. the possible relationship between ocular symptomatology, tear volume and tear break-up time (TBUT) and lipocalin, lactoferrin and lysozyme concentrations in the tear film were explored in a group of symptomatic dry-eyed postmenopausal (PM) women. PMID: 26366224
    4. Tear lysozyme, lactoferrin and lipocalin concentrations were determined via electrophoresis and the results for patients with or without eyelid tumors were compared. PMID: 25914748
    5. the crosstalk of dendritic cells with lipocalins alone has the potential to direct the type of immune response to these particular antigens. PMID: 26218644
    6. Serum concentrations of LCN1 and LCN2 were both elevated in patients with COPD. PMID: 24920892
    7. Tear lipocalin (TLC) is a major protein in tears and has a large ligand-binding cavity that allows the lipocalin to bind an extensive and diverse set of lipophilic molecules. PMID: 21791187
    8. Study has identified the first protein, lipocalin-1, in the secretome of human blastocysts that is associated with chromosome aneuploidy. PMID: 21324447
    9. The conserved disulfide bond of human tear lipocalin modulates conformation and lipid binding in a ligand selective manner.( PMID: 21466861
    10. Tear lipocalin with the bound artificial ligand 1,4-butanediol has been crystallized in space group P2(1) with four protein molecules in the asymmetric unit and its X-ray structure has been solved at 2.6 A resolution. PMID: 19770509
    11. The N-terminal part of recombinant human tear lipocalin/von Ebner's gland protein confers cysteine proteinase inhibition depending on the presence of the entire cystatin-like sequence motifs. PMID: 11727836
    12. Lcn-1 is specifically produced by corticotrophs PMID: 11850445
    13. LIMR mediating internalization of lipocalin-1 (Lcn-1) in NT2 cells, leading to its degradation. PMID: 12591932
    14. structure, function, and mechanism of action [review] PMID: 12613960
    15. Tear lipocalin is probable protein carrier for vitamin E tears and is candidate to specifically deliver vitamin E as antioxidant to corneal epithelium. PMID: 12613961
    16. Tear surface tension depends partly on presence of tear lipocalin/lipid complex. Tear proteins and lipid-free tear lipocalin lower surface tension. PMID: 12613963
    17. pH-driven ligand release involves ionization changes in several titratable residues associated with CD and EF loop apposition and occlusion of the calyx PMID: 15461462
    18. structural analysis sheds new light on the ligand binding activity of this functionally obscure but abundant human lipocalin PMID: 15489503
    19. Lipocalin is a novel autoantigen target in Sjogren's syndrome. PMID: 16249071
    20. Hydrodynamic and solution properties of lipocalin from human tears show that the protein size and topology are the major determinants of rotational correlation time and a reason for deviation from the Stokes-Einstein relationship. PMID: 17869594
    21. Selective displacement of ANS molecules from the ANS-apoTL complex by stearic acid discriminates the internal and external binding sites. PMID: 17945179
    22. Tear lipocalin is the principal endonuclease in human tear fluid. PMID: 18334931
    23. Results suggest that the excited protein states in tear lipocalin are not unique but consist of many substates. PMID: 19586017

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Calycin superfamily, Lipocalin family
  • 組織特異性:
    Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 6525

    OMIM: 151675

    KEGG: hsa:3933

    STRING: 9606.ENSP00000263598

    UniGene: Hs.530311



主站蜘蛛池模板: 国产99在线 | 中国| 1区2区3区高清视频| 国内精品乱码卡一卡2卡麻豆| 潮喷无码正在播放| 亚洲国产精品久久久久久无码| 欧美一区二区 | 久久亚洲精品无码爱剪辑 | 久久99国产精品久久99果冻传媒| 中文乱码字幕视频观看网站免费 | 成 人影片 免费观看在线| 亚洲伊人久久大香线蕉av| 国产免费无遮挡吸乳视频 | 午夜熟女插插xx免费视频| 欧美va亚洲va在线观看日本| 中文成人无码精品久久久动漫 | 亚洲桃色天堂网| 一本一道久久a久久精品综合| 国产区女主播在线观看| 免费人成网站在线观看欧美| 中文字幕大看蕉在线观看| 青青草视频在线观看| 精品黑人一区二区三区| 国产精品国产三级国产an| 太粗太深了太紧太爽了动态图男男 | 成人无码α片在线观看不卡| 亚洲第一页综合图片自拍| 10000部拍拍拍免费视频| 狠狠色狠狠人格综合| 欧美乱码卡一卡二卡四卡免费| 人人插人人插人人爽| 樱花草在线社区www韩国| 十八禁午夜福利免费网站| 大又大又粗又硬又爽少妇毛片| 欧美色综合天天久久综合精品| 2020精品自拍视频曝光| 夜色爽爽影院18禁妓女影院| 无码精品尤物一区二区三区| 中文字幕无码毛片免费看| 麻豆国产原创视频在线播放 | 国产婷婷色综合av蜜臀av| 国内偷自第一区二区三区|