在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Interferon kappa (IFNK)

  • 中文名稱:
    人IFNK重組蛋白
  • 貨號:
    CSB-YP889172HUk3
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    (IFN-kappa)
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    80.1 kDa
  • 表達區域:
    28-207aa
  • 氨基酸序列
    LDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-PDI-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play a role in the regulation of immune cell function. Cytokine that imparts cellular protection against viral infection in a species-specific manner. Activates the interferon-stimulated response element signaling pathway. It is able to directly modulate cytokine release from monocytes and dendritic cells. Binds heparin.
  • 基因功能參考文獻:
    1. investigation of common variable immunodeficiency (CVID) from 2 German families; report on the occurrence of a common and one novel truncating IFNK mutation in cases with CVID; the frequency distribution of c.30_31insTGTT in cases and controls as well as the observed segregation patterns in CVID families exclude IFNK mutations as major risk factor in CVID PMID: 28324805
    2. These results suggest that high-risk human papillomavirus 31 target interferon kappa to prevent Sp100 expression and identify Sp100 as an interferon-stimulated gene with anti-human papillomavirus activity. PMID: 26491169
    3. This study demonstrates that E2 proteins of high risk human papillomavirus reduce STING and IFN-kappa transcription. PMID: 24614210
    4. The viral E6 and E7 oncogenes are sufficient for interferon-kappa repression, with E6 being mainly responsible. PMID: 21849431
    5. IFN-kappa is down-regulated in cervical keratinocytes harboring HPV, which may be a contributing factor in the progression of a cervical lesion PMID: 20479716
    6. Studied IFNK single nucleotide polymorphisms in 3982 Systemic lupus erythematosus cases and 4275 controls. PMID: 20706608
    7. IFN-kappa is able to directly modulate cytokine release from monocytes and dendritic cells, inhibit inducible IL-12 release from monocytes, and bind strongly to heparin. PMID: 12391192
    8. This is the first report showing an epigenetic silencing of type I IFN after HPV16 oncogene expression PMID: 19887612

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Alpha/beta interferon family
  • 組織特異性:
    Expressed in keratinocytes, monocytes and in resting dendritic cells.
  • 數據庫鏈接:

    HGNC: 21714

    OMIM: 615326

    KEGG: hsa:56832

    STRING: 9606.ENSP00000276943

    UniGene: Hs.591083



主站蜘蛛池模板: 精品黑人一区二区三区| 少妇人妻无码专区视频| 久久精品人妻无码一区二区三区| 四虎影视久久久免费观看| 国产丝袜在线精品丝袜不卡| 欧美白人最猛性xxxxx| 久久午夜神器| 99精品视频在线观看| 日韩精品无码免费一区二区三区 | 天堂中文在线资源| 亚洲一区二区制服在线| 中文字幕韩国三级理论| 一本无码久本草在线中文字幕dvd| 精品熟人妻一区二区三区四区不卡| 国产福利萌白酱精品tv一区| 国产成人精品亚洲精品| 各种少妇正面bbw撒尿| 真人抽搐一进一出gif| 亚洲高请码在线精品av| 欧美做受又硬又粗又大视频| 天天躁日日躁狠狠躁欧美老妇 | 波多野结衣一区二区免费视频| 久久人人爽人人爽人人片av高清| 国产综合在线观看| 国模国产精品嫩模大尺度视频| 亚洲精品无码鲁网中文电影 | 国产亚洲人成a在线v网站| 强迫大乳人妻中文字幕| 中文字幕人妻丝袜成熟乱 | 丰腴饱满的极品熟妇| 亚洲高清无码加勒比| 激情综合婷婷丁香五月蜜桃| 久久精品麻豆日日躁夜夜躁| 日韩av无码国产精品| 曰的好深好爽免费视频网站| 国产欧美一区二区三区免费视频| 亚洲国产精品成人一区二区在线| 国产高清乱理伦片| 亚洲国产欧美在线人成app| 国产熟睡乱子伦午夜视频| 日本两人免费观看的视频|