在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Integrator complex subunit 3 (INTS3), partial

  • 中文名稱:
    人INTS3重組蛋白
  • 貨號:
    CSB-YP011761HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人INTS3重組蛋白
  • 貨號:
    CSB-EP011761HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人INTS3重組蛋白
  • 貨號:
    CSB-EP011761HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人INTS3重組蛋白
  • 貨號:
    CSB-BP011761HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人INTS3重組蛋白
  • 貨號:
    CSB-MP011761HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    INTS3
  • Uniprot No.:
  • 別名:
    INTS3; C1orf193; C1orf60; Integrator complex subunit 3; Int3; SOSS complex subunit A; Sensor of single-strand DNA complex subunit A; SOSS-A; Sensor of ssDNA subunit A
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the Integrator (INT) complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
  • 基因功能參考文獻:
    1. In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites. PMID: 23986477
    2. INTS3 is part of an ssDNA-binding heterotrimeric complex, SOSS which is involved in the maintenance of genome stability. PMID: 19683501
    3. INT3 plays a key role in the DNA damage response PMID: 19759019
    4. INTS3 controls the hSSB1-mediated DNA damage response. PMID: 19786574
  • 亞細胞定位:
    Nucleus. Cytoplasm. Note=Localizes to nuclear foci following DNA damage.
  • 蛋白家族:
    Integrator subunit 3 family
  • 數據庫鏈接:

    HGNC: 26153

    OMIM: 611347

    KEGG: hsa:65123

    STRING: 9606.ENSP00000318641

    UniGene: Hs.438723



主站蜘蛛池模板: 无码专区丰满人妻斩六十路| 欧美又粗又大又硬又长又爽视频| 亚洲精品国产一区二区三| 亚洲乱码中文字幕综合234| 两个人看的www免费视频中文| 男女裸交免费无遮挡全过程 | 中文字幕人妻熟女av| 日韩免费一区二区三区高清| 亚洲人成网站在小说| 色鬼7777久久| 国产欧美日韩国产高清| 亚洲成在人线在线播放无码vr| 狠狠躁天天躁中文字幕无码| 无码高潮爽到爆的喷水视频| 欧美野外疯狂做受xxxx高潮| 国产免费午夜福利在线播放11| 国产 制服丝袜 动漫在线| 人妻丰满熟妇av无码区乱| 两根大肉大捧一进一出好爽视频| 人妻少妇伦在线麻豆m电影| 国产成人一区二区三区免费| 亚洲成色www久久网站| 亚洲高清无在码在线电影不卡 | 国产欧美va欧美va香蕉在| 国产制服丝袜亚洲高清| 四库影院永久四虎精品国产| 欧美又大又色又爽aaaa片| 国产精品制服| 天天躁夜夜躁天干天干2020| 青青草免费公开视频| 无套内谢老熟女| 欧洲美女黑人粗性暴交视频| 一区二区三区四区在线不卡高清| 无码人妻一区二区三区免费手机| 国色天香成人网| 国产精品久久香蕉免费播放| 性色香蕉av久久久天天网| 欧美激情综合五月色丁香| 四虎永久在线高清国产精品| 久久午夜无码鲁丝片直播午夜精品 | 久久精品人成免费|