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Recombinant Human Inositol-3-phosphate synthase 1 (ISYNA1)

  • 中文名稱:
    人ISYNA1重組蛋白
  • 貨號:
    CSB-YP011856HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ISYNA1重組蛋白
  • 貨號:
    CSB-EP011856HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人ISYNA1重組蛋白
  • 貨號:
    CSB-EP011856HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ISYNA1重組蛋白
  • 貨號:
    CSB-BP011856HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人ISYNA1重組蛋白
  • 貨號:
    CSB-MP011856HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ISYNA1
  • Uniprot No.:
  • 別名:
    hINO1; hIPS; INO1; INO1_HUMAN; INOS; Inositol 3 phosphate synthase 1; Inositol-3-phosphate synthase 1; IPS ; IPS 1; ISYNA 1; Isyna1; MI 1 P synthase; MI-1-P synthase; MI1P synthase; MIP synthase; Myo inositol 1 phosphate synthase A1; Myo-inositol 1-phosphate synthase A1; Myo-inositol-1-phosphate synthase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-558
  • 氨基酸序列
    MEAAAQFFVE SPDVVYGPEA IEAQYEYRTT RVSREGGVLK VHPTSTRFTF RTARQVPRLG VMLVGWGGNN GSTLTAAVLA NRLRLSWPTR SGRKEANYYG SLTQAGTVSL GLDAEGQEVF VPFSAVLPMV APNDLVFDGW DISSLNLAEA MRRAKVLDWG LQEQLWPHME ALRPRPSVYI PEFIAANQSA RADNLIPGSR AQQLEQIRRD IRDFRSSAGL DKVIVLWTAN TERFCEVIPG LNDTAENLLR TIELGLEVSP STLFAVASIL EGCAFLNGSP QNTLVPGALE LAWQHRVFVG GDDFKSGQTK VKSVLVDFLI GSGLKTMSIV SYNHLGNNDG ENLSAPLQFR SKEVSKSNVV DDMVQSNPVL YTPGEEPDHC VVIKYVPYVG DSKRALDEYT SELMLGGTNT LVLHNTCEDS LLAAPIMLDL ALLTELCQRV SFCTDMDPEP QTFHPVLSLL SFLFKAPLVP PGSPVVNALF RQRSCIENIL RACVGLPPQN HMLLEHKMER PGPSLKRVGP VAATYPMLNK KGPVPAATNG CTGDANGHLQ EEPPMPTT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds.
  • 基因功能參考文獻:
    1. analysis of how myo-inositol-3-phosphate synthase is regulated by phosphorylation PMID: 23902760
    2. MIP synthase expressed in developing fetal liver and shows optima pH between 7.0 and 7.5. PMID: 22707096
    3. Upregulation occurs through the interaction of several low-affinity E2F binding motifs present in the minimal promoter. PMID: 15464731
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Myo-inositol 1-phosphate synthase family
  • 組織特異性:
    Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon.
  • 數據庫鏈接:

    HGNC: 29821

    OMIM: 611670

    KEGG: hsa:51477

    STRING: 9606.ENSP00000337746

    UniGene: Hs.405873



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