在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Immunoglobulin superfamily member 8 (IGSF8), partial

  • 中文名稱:
    人IGSF8重組蛋白
  • 貨號:
    CSB-YP856887HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人IGSF8重組蛋白
  • 貨號:
    CSB-EP856887HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人IGSF8重組蛋白
  • 貨號:
    CSB-EP856887HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人IGSF8重組蛋白
  • 貨號:
    CSB-BP856887HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人IGSF8重組蛋白
  • 貨號:
    CSB-MP856887HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CD316; CD316 antigen; CD81 partner 3; CD81P3; EWI-2; EWI2; Glu-Trp-Ile EWI motif-containing protein 2; igsf-8; IgSF8; IGSF8_HUMAN; Immunoglobulin superfamily member 8; Immunoglobulin superfamily member 8 precursor; KCT-4; KCT4; Keratinocytes-associated transmembrane protein 4; LIR-D1; PGRL; Prostaglandin regulatory-like protein
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
  • 基因功能參考文獻:
    1. EWI-2 negatively regulates TGF-beta signaling and its downstream events including cytostasis (in vitro and in vivo), EMT-like changes, cell migration, CD271-dependent invasion, and lung metastasis (in vivo). PMID: 25656846
    2. Authors demonstrated that EWI-2wint promotes CD81 clustering and confinement in CD81-enriched areas. PMID: 23351194
    3. The EWI-2/alpha-actinin complex is involved in regulation of the actin cytoskeleton at T cell immune and virological synapses, providing a link between membrane microdomains and the formation of polarized membrane structures involved in T cell recognition. PMID: 22689882
    4. analysis of interacting regions of CD81 and two of its partners, EWI-2 and EWI-2wint, and their effect on hepatitis C virus infection PMID: 21343309
    5. EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells. PMID: 12750295
    6. EWI-2-dependent reorganization of alpha4beta1-CD81 complexes on the cell surface is responsible for EWI-2 effects on integrin-dependent morphology and motility functions PMID: 15070678
    7. EWI proteins EWI-2 and EWI-F, alpha3beta1 and alpha6beta4 integrins, and protein palmitoylation have contrasting effects on cell surface CD9 organization PMID: 16537545
    8. EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins PMID: 16690612
    9. Important functions of recently activated dendritic cells are thus critically modulated by the newly discovered HSPA8-EWI-2 interaction. PMID: 17785435
    10. CD81 partner EWI-2wint inhibits hepatitis C virus entry [EWI-2wint] PMID: 18382656
    11. EWI-2 causes a substantial molecular reorganization of multiple molecules known to affect proliferation and/or invasion of astrocytes and/or glioblastomas. PMID: 19107234

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass membrane protein.
  • 組織特異性:
    Expressed in brain, kidney, testis, liver and placenta with moderate expression in all other tissues. Detected on a majority of B-cells, T-cells, and natural killer cells but not on monocytes, polynuclear cells and platelets.
  • 數據庫鏈接:

    HGNC: 17813

    OMIM: 606644

    KEGG: hsa:93185

    STRING: 9606.ENSP00000316664

    UniGene: Hs.332012



主站蜘蛛池模板: 亚洲综合久久一本久道| 99久久无码一区人妻a黑| 色综合久久久久综合99| 亚洲欧洲免费三级网站| 成 人 网 站 免费 在线| 性色欲网站人妻丰满中文久久不卡| 伊人久久大香线蕉av一区| 又色又爽又黄的吃奶视频免费观看| 五月婷婷久久草| 亚洲影院丰满少妇中文字幕无码| 51国产偷自视频区视频| 色噜噜狠狠一区二区三区果冻| 久久青青草原国产毛片| 日日摸日日碰夜夜爽无| 国产女人18毛片水真多| 色爱区综合五月激情| 亚洲精品久久久久久久观小说| 亚洲国产成人久久综合一区77| 天天躁日日躁狠狠躁性色avq| 成 年 人 黄 色 大 片大 全| 无码午夜成人1000部免费视频| 久久精品国产男包| 亚洲日本va中文字幕亚洲| 中文字幕人乱码中文字幕| 在线日韩日本国产亚洲| 人人玩人人添人人澡| 影音先锋啪啪av资源网站| 国语自产少妇精品视频| 国产a国产片国产| 久久精品香蕉绿巨人登场| 国产尤物精品自在拍视频首页| 国产成人精品优优av| 久久99精品国产.久久久久| 无码不卡中文字幕av| av一区二区国产在线视频| 试看120分钟做受小视频| 在线 无码 中文字幕 强 乱| 亚洲精品国产一二三无码av| 精品亚洲麻豆1区2区3区| 国产美女无遮挡裸色视频| 99热国产这里只有精品6|