在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Homer protein homolog 3 (HOMER3)

  • 中文名稱:
    人HOMER3重組蛋白
  • 貨號:
    CSB-YP878880HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人HOMER3重組蛋白
  • 貨號:
    CSB-EP878880HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人HOMER3重組蛋白
  • 貨號:
    CSB-EP878880HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人HOMER3重組蛋白
  • 貨號:
    CSB-BP878880HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人HOMER3重組蛋白
  • 貨號:
    CSB-MP878880HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HOME3_HUMAN; HOMER 3; Homer 3D protein ; Homer homolog 3 (Drosophila); Homer neuronal immediate early gene 3; Homer protein homolog 3; Homer-3; Homer3; VESL3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-361
  • 氨基酸序列
    MSTAREQPIF STRAHVFQID PATKRNWIPA GKHALTVSYF YDATRNVYRI ISIGGAKAII NSTVTPNMTF TKTSQKFGQW ADSRANTVYG LGFASEQHLT QFAEKFQEVK EAARLAREKS QDGGELTSPA LGLASHQVPP SPLVSANGPG EEKLFRSQSA DAPGPTERER LKKMLSEGSV GEVQWEAEFF ALQDSNNKLA GALREANAAA AQWRQQLEAQ RAEAERLRQR VAELEAQAAS EVTPTGEKEG LGQGQSLEQL EALVQTKDQE IQTLKSQTGG PREALEAAER EETQQKVQDL ETRNAELEHQ LRAMERSLEE ARAERERARA EVGRAAQLLD VSLFELSELR EGLARLAEAA P
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA.
  • 基因功能參考文獻:
    1. Homer3 acts as a scaffold that spatially organizes actin assembly to support neutrophil polarity and motility downstream of GPCR activation. PMID: 25739453
    2. Interaction of the protein with amyloid precursor protein is regulated by calcium homeostasis. PMID: 24792907
    3. Loss of Homer3 is associated with acute myeloid leukemia. PMID: 23725168
    4. Homer3 specifically associates with a novel ubiquitin-like domain in the I kappa B kinase (IKK) beta subunit of the IKK complex. PMID: 20693425
    5. Homer-3 may be involved in the regulation of SRE activation in T cells via interaction between its EVH1 domain and C/EBP beta. PMID: 14645007
    6. Fat1 exhibit co-localisation with Homer-3 in cellular protrusions and at the plasma membrane of HeLa cells PMID: 16979624
    7. study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin PMID: 18218901

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 蛋白家族:
    Homer family
  • 數據庫鏈接:

    HGNC: 17514

    OMIM: 604800

    KEGG: hsa:9454

    STRING: 9606.ENSP00000376162

    UniGene: Hs.720208



主站蜘蛛池模板: 三级做a全过程在线观看| 麻豆av福利av久久av| 亚洲国产日韩欧美一区二区三区| 女人被男人桶30分钟无遮挡动态图| 亚洲中文字幕无码卡通动漫野外| 97久久草草超级碰碰碰| 成年女性特黄午夜视频免费看| 东方aⅴ免费观看久久av| 久久综合a∨色老头免费观看| 国产亚洲精品在av| 国产精品久久久久久无毒不卡 | 中字幕久久久人妻熟女天美传媒 | 免费拍拍拍网站| 熟妇丰满多毛的大隂户| 久久青青草原国产毛片| 亚洲欧美中文高清在线专区| 欧美牲交a欧美牲交aⅴ免费| 精品久久久久久无码人妻| 四房播色综合久久婷婷| 国产精品亚洲欧美大片在线观看| 日产精品中文一区二区三区| 国产精品福利一区二区| 国产成人精品综合在线观看 | 欧洲精品va无码一区二区三区| 亚洲人色婷婷成人网站在线观看| 亚洲精品无码永久在线观看性色| 狠狠色噜噜狠狠狠狠888奇禾| 成人av片在线观看免费| 高清视频在线观看一区二区三区 | 亚洲性色av性色在线观看| 99亚洲乱人伦aⅴ精品| 奇米影视888欧美在线观看 | 国产做爰又粗又大又爽动漫| 欧美肥老太牲交大战| 中文字幕人成乱码熟女免费| 国产成人午夜福利在线播放| 亚洲欧美日产综合在线| 婷婷成人综合激情在线视频播放| 无码精品国产dvd在线观看9久| 秋霞在线观看片无码免费不卡| 女人高潮抽搐喷液30分钟视频|