在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOMER3 Antibody

HOMER3 Antibody

  • 中文名稱：
    HOMER3兔多克隆抗體
  • 貨號：
    CSB-PA010638GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    HOME3_HUMAN antibody; HOMER 3 antibody; Homer 3D protein antibody; Homer homolog 3 (Drosophila) antibody; Homer neuronal immediate early gene 3 antibody; Homer protein homolog 3 antibody; Homer-3 antibody; Homer3 antibody; VESL3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human HOMER3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA.
  • 基因功能參考文獻：
    1. Homer3 acts as a scaffold that spatially organizes actin assembly to support neutrophil polarity and motility downstream of GPCR activation. PMID: 25739453
    2. Interaction of the protein with amyloid precursor protein is regulated by calcium homeostasis. PMID: 24792907
    3. Loss of Homer3 is associated with acute myeloid leukemia. PMID: 23725168
    4. Homer3 specifically associates with a novel ubiquitin-like domain in the I kappa B kinase (IKK) beta subunit of the IKK complex. PMID: 20693425
    5. Homer-3 may be involved in the regulation of SRE activation in T cells via interaction between its EVH1 domain and C/EBP beta. PMID: 14645007
    6. Fat1 exhibit co-localisation with Homer-3 in cellular protrusions and at the plasma membrane of HeLa cells PMID: 16979624
    7. study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin PMID: 18218901

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
  • 蛋白家族：
    Homer family
  • 數據庫鏈接：

    HGNC: 17514

    OMIM: 604800

    KEGG: hsa:9454

    STRING: 9606.ENSP00000376162

    UniGene: Hs.720208



主站蜘蛛池模板： 中文字幕无码人妻aaa片| 国产精品亚亚洲欧关中字幕| 国产成人av在线一区二区三区| 超碰aⅴ人人做人人爽欧美| 成人无码www免费视频| 免费刺激性视频大片区| 无码免费无线观看在线视| 免费无码又爽又刺激激情视频软件| 四虎永久在线精品免费网站| 麻豆乱码国产一区二区三区| 亚洲中文字幕丝祙制服| 亚洲 欧美 自拍 美腿 卡通| 永久中文字幕免费视频网站| 国模杨依粉嫩蝴蝶150p| 秋霞在线观看秋| 樱花草在线社区www中国中文| 中国做爰国产精品视频| 亚洲丰满熟妇在线播放电影全集 | 成年女人毛片免费视频| 尤物av无码色av无码| 新国产精品视频福利免费| 国产av国片精品有毛| 国产伦孑沙发午休精品| 成人性生交大片免费看96| 欧洲日本一线二线三线区本庄铃| 最大胆裸体人体牲交免费| 日本爽爽爽爽爽爽在线观看免| 欧美老肥妇做爰bbww| 亚洲国产成人久久久网站| 美女18禁一区二区三区视频| 国产成人精品久久亚洲高清不卡| 忘忧草社区中文字幕www| 奇米777四色成人影视| 亚洲国产精品一区二区www| 国产麻豆9l精品三级站| 国产精品久久自在自线不卡| 99c视频色欲在线| 一本大道久久久久精品嫩草| 无码人妻丰满熟妇精品区| 免费观看在线a毛片| 国产成人久久av免费|