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  2. 蛋白
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  4. Recombinant Human Heat shock protein beta-3 (HSPB3)

Recombinant Human Heat shock protein beta-3 (HSPB3)

  • 中文名稱：
    人HSPB3重組蛋白
  • 貨號(hào)：
    CSB-YP614265HU
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人HSPB3重組蛋白
  • 貨號(hào)：
    CSB-EP614265HU
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人HSPB3重組蛋白
  • 貨號(hào)：
    CSB-EP614265HU-B
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人HSPB3重組蛋白
  • 貨號(hào)：
    CSB-BP614265HU
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人HSPB3重組蛋白
  • 貨號(hào)：
    CSB-MP614265HU
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    HSPB3
  • Uniprot No.：
  • 別名：
    HSPB3; HSP27; HSPL27; Heat shock protein beta-3; HspB3; Heat shock 17 kDa protein; HSP 17; Protein 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-150
  • 氨基酸序列
    MAKIILRHLI EIPVRYQEEF EARGLEDCRL DHALYALPGP TIVDLRKTRA AQSPPVDSAA ETPPREGKSH FQILLDVVQF LPEDIIIQTF EGWLLIKAQH GTRMDEHGFI SRSFTRQYKL PDGVEIKDLS AVLCHDGILV VEVKDPVGTK
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Inhibitor of actin polymerization.
  • 基因功能參考文獻(xiàn)：
    1. HSPB2 competes with HSPB8 for binding to BAG3. In contrast, HSPB3 negatively regulates HSPB2 association with BAG3. PMID: 28181153
    2. This study showed that the endogenous HSPB3 protein distribution in the spinal cords of chicken and mouse embryos and in the postnatal nervous system of human. PMID: 27567740
    3. HspB3 exhibits chaperone-like activity. PMID: 22610661
    4. an HSPB3 mutation associated with an axonal motor neuropathy PMID: 20142617
    5. Our results suggest that a variety of oligomers composed of different proportions of different sHSPs may form in cell types expressing multiple sHSPs. PMID: 16225851

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  • 相關(guān)疾病：
    Neuronopathy, distal hereditary motor, 2C (HMN2C)
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
  • 蛋白家族：
    Small heat shock protein (HSP20) family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 5248

    OMIM: 604624

    KEGG: hsa:8988

    STRING: 9606.ENSP00000303394

    UniGene: Hs.41707



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