在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Heat shock factor-binding protein 1 (HSBP1), partial

  • 中文名稱:
    人HSBP1重組蛋白
  • 貨號:
    CSB-RP004544h
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Heat shock factor binding protein 1; Heat shock factor-binding protein 1; HSBP1; HSBP1_HUMAN; HSF1BP; Nasopharyngeal carcinoma associated antigen 13; Nasopharyngeal carcinoma-associated antigen 13; NPC A 13 ; NPC-A-13; NPCA 13
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    35.5kDa
  • 表達區域:
    1-75aa
  • 氨基酸序列
    MAETDPKTVQDLTSVVQTLLQQMQDKFQTMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELESENKIPATQK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process.
  • 基因功能參考文獻:
    1. HSPB1 protects cells against proapoptotic agents when expressed at high level, while inhibition of its expression has been found to predispose cells to apoptosis. PMID: 28828227
    2. Results presented here show that acquisition of a positive charge in HSBP1, either by protonation of His124 or its substitution by lysine, reduces the stability of the dimer interface of the alpha-crystallin domain, increases oligomeric size, and modestly increases chaperone activity. PMID: 28332148
    3. HSBP1 is crucial for regulating resistance to radiotherapy of oral squamous epithelial carcinoma cells by inducing stem-like status. PMID: 24816843
    4. HspBP1 inhibited the cytotoxic activity of the Tag7-Hsp70 complex secreted by lymphocytes. HspBP1 PMID: 21247889
    5. This study reports the crystal structure of a degradation-resistant fragment of HSBP1. A continuous, long-helix conformation of HSBP1 assembles into a coiled-coil three-helix bundle and subsequently into an elongated, symmetrical hexamer. PMID: 18767159
    6. HSBP likely mediates its function through its trimerization domain. PMID: 11679589

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    HSBP1 family
  • 數據庫鏈接:

    HGNC: 5203

    OMIM: 604553

    KEGG: hsa:3281

    STRING: 9606.ENSP00000392896

    UniGene: Hs.250899



主站蜘蛛池模板: 很色很爽很黄裸乳视频| 成在线人永久免费视频播放| 中文字幕在线观看亚洲视频| 精品国产美女av久久久久| 国产亚洲另类无码专区| 久久精品无码一区二区三区免费| 国产成人亚洲精品无码h在线| 精品无码av不卡一区二区三区| 欧美人与动zozo在线播放| 射精区-区区三区| 国产精自产拍久久久久久蜜| 风韵饥渴少妇在线观看| 成人无遮挡18禁免费视频| 国产精品丝袜高跟鞋| 性裸交a片一区二区三区| 国产精品性夜天天拍拍2021| 亚洲人成网站18禁止| 后入到高潮免费观看| 免费看国产曰批40分钟| 日韩亚洲中字无码一区二区三区| 成人免费播放视频777777| 日本少妇高潮喷水xxxxxxx| 国产互换人妻hd| 提莫影院av毛片入口| 亚洲中文字幕无码av在线| 亚洲 自拍 另类 欧美 综合| 免费国产午夜理论片不卡| 宅男色影视亚洲人在线| 亚洲日韩一区二区三区| 欧美牲交a欧美牲交aⅴ图片| 久久精品人成免费| 亚洲欧美成人一区二区在线电影 | 国产未成女一区二区| 日日碰狠狠添天天爽无码| 免费观看18禁无遮挡真人网站 | 欧美成人免费va影院高清| 亚洲无线卡一卡二| 夜鲁鲁鲁夜夜综合视频欧美| 国产sm调教折磨视频失禁| 亚洲欧美日韩综合av| 麻豆亚洲一区|