在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HSBP1 Antibody, Biotin conjugated

HSBP1 Antibody, Biotin conjugated

  • 中文名稱：
    HSBP1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA00454D0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HSBP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Heat shock factor binding protein 1 antibody; Heat shock factor-binding protein 1 antibody; HSBP1 antibody; HSBP1_HUMAN antibody; HSF1BP antibody; Nasopharyngeal carcinoma associated antigen 13 antibody; Nasopharyngeal carcinoma-associated antigen 13 antibody; NPC A 13 antibody; NPC-A-13 antibody; NPCA 13 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Heat shock factor-binding protein 1 protein (1-75AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process.
  • 基因功能參考文獻：
    1. HSPB1 protects cells against proapoptotic agents when expressed at high level, while inhibition of its expression has been found to predispose cells to apoptosis. PMID: 28828227
    2. Results presented here show that acquisition of a positive charge in HSBP1, either by protonation of His124 or its substitution by lysine, reduces the stability of the dimer interface of the alpha-crystallin domain, increases oligomeric size, and modestly increases chaperone activity. PMID: 28332148
    3. HSBP1 is crucial for regulating resistance to radiotherapy of oral squamous epithelial carcinoma cells by inducing stem-like status. PMID: 24816843
    4. HspBP1 inhibited the cytotoxic activity of the Tag7-Hsp70 complex secreted by lymphocytes. HspBP1 PMID: 21247889
    5. This study reports the crystal structure of a degradation-resistant fragment of HSBP1. A continuous, long-helix conformation of HSBP1 assembles into a coiled-coil three-helix bundle and subsequently into an elongated, symmetrical hexamer. PMID: 18767159
    6. HSBP likely mediates its function through its trimerization domain. PMID: 11679589

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    HSBP1 family
  • 數據庫鏈接：

    HGNC: 5203

    OMIM: 604553

    KEGG: hsa:3281

    STRING: 9606.ENSP00000392896

    UniGene: Hs.250899



主站蜘蛛池模板： 久久精品国产av一区二区三区| 国产精品无码av不卡顿| 国产亚洲美女精品久久久2020| 精品无码无人网站免费视频| 久久99精品久久久久久齐齐 | 亚洲 熟女 久久 国产| 先锋影音av最新资源| 国产女人18毛片水真多18精品| 国产熟妇高潮叫床视频播放| 国产精品成人网站| 国产精品国产午夜免费看福利| 中文字幕制服丝袜人妻动态图| 97碰碰碰人妻无码视频| 东方aⅴ免费观看久久av| 亚洲欧美综合精品成人导航| 无码av永久免费专区麻豆| 中文字幕乱码在线播放| 在线观看无码不卡av中文| 国产99视频精品免费视频6| 女人被男人躁得好爽免费视频| 国产露脸无套对白在线播放| 樱花草在线社区www韩国| 国产八十老太另类| 国产偷国产偷亚洲清高app| 丰满多毛的大隂户视频| 色综合网天天综合色中文 | 亚洲人成精品久久久久桥| 少妇大叫太大太爽受不了在线观看| 精品一二三区久久aaa片| 欧美疯狂做受xxxxx高潮| 亚洲性夜夜综合久久7777| 野花社区免费观看在线www| 特级做a爰片毛片免费69| 亚洲国产成人综合一区二区三区| 夜精品一区二区无码a片 | 无线乱码一二三区免费看| 丰满熟女人妻一区二区三| 少妇又紧又色又爽又刺激视频| 中文字幕无码精品三级在线电影| 337p日本欧洲亚洲大胆精品| 波多野结衣在线播放|