在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Guanine nucleotide-binding protein G (s) subunit alpha isoforms short (GNAS)

In Stock
  • 中文名稱:
    人GNAS重組蛋白
  • 品名簡稱:
    Recombinant Human GNAS protein
  • 貨號:
    CSB-EP352389HU
  • 說明書:
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Adenylate cyclase-stimulating G alpha protein; AHO; alternative gene product encoded by XL-exon; C20orf45; extra large alphas protein; GNAS; GNAS complex locus; GNAS1; GNAS1 gene, formerly; GNAS1, formerly; GNAS2_HUMAN; GPSA; GSA; GSP; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1; guanine nucleotide regulatory protein; Guanine nucleotide-binding protein G(s) subunit alpha isoforms short; guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; NESP; neuroendocrine secretory protein; PHP1A; PHP1B; PHP1C; POH; protein ALEX; secretogranin VI
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    61.7kDa
  • 表達(dá)區(qū)域:
    1-394aa
  • 氨基酸序列
    MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 產(chǎn)品描述:

    The recombinant Human GNAS?protein is made through genetic engineering, also called gene splicing or recombinant DNA technology. By putting Human GNAS genes into the genetic material of the E.coli system. These microorganisms can be used as factories or producers to make proteins for medical, academic and research uses. DNA to be manipulated it must be placed within a “transport vehicle” in which proteins may be produced from the genetic code of the DNA. The host cells used for Human GNAS protein synthesis are E.coli cells, the whole production processes include isolation of GNAS?gene, amplification of GNAS?gene, cloning, GNAS gene selection, and expression, and the GNAS protein purification, the vector contains N-terminal 6xHis-SUMO tag?in addition to the specific DNA sequence, this facilitates the purification of the recombinant protein and it’s finally detected with a purity of 90%+?by SDS-PAGE.

    GNAS is the encoding gene for the α-subunit of the stimulatory G protein (Gsα), a widely expressed signaling protein that is required for the actions of many hormones and other endogenous molecules by generating cAMP. Mutations in GNAS have been highly linked to McCune-Albright syndrome, characterized by developmental delay, short stature, and skeletal aberrations. GNAS mutation also regulates mucin expression.

  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.
  • 相關(guān)疾病:
    Albright hereditary osteodystrophy (AHO); Pseudohypoparathyroidism 1A (PHP1A); McCune-Albright syndrome (MAS); Progressive osseous heteroplasia (POH); ACTH-independent macronodular adrenal hyperplasia 1 (AIMAH1); Pseudohypoparathyroidism 1B (PHP1B); GNAS hyperfunction (GNASHYP); Pseudohypoparathyroidism 1C (PHP1C)
  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor.
  • 蛋白家族:
    G-alpha family, G(s) subfamily
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4392

    OMIM: 103580

    KEGG: hsa:2778

    UniGene: Hs.125898



主站蜘蛛池模板: 国产日韩未满十八禁止观看| 男人av无码天堂| 在线观看一区二区三区国产免费| 少妇和邻居做不戴套视频| 2020国产精品午夜福利在线观看| 欧美午夜一区二区福利视频| www片香蕉内射在线88av8| 动漫av一区二区在线观看| 国产精品美女久久久久网站浪潮| 国产女人18毛片水真多| 久久久www成人免费毛片| 最新网站亚洲人成无码| 亚洲国产av导航第一福利网| 欧美成人精品午夜免费影视| 麻豆妓女爽爽一区二区三| 宅宅少妇无码| 98色婷婷在线| 四虎永久在线高清国产精品| 亚洲乱亚洲乱少妇无码99p| 国精产品一区一区三区免费视频| 精品人妻系列无码专区| 中国少妇xxxx做受| 中国孕妇变态孕交xxxx| 久久久久国精品产熟女久色| 成人a大片在线观看| 亚洲成av人片天堂网| 人妻久久久一区二区三区| 国产精品人成视频国模| 久久66热人妻偷产精品9| 国精产品999国精产品官网| 风流少妇按摩来高潮| 97se亚洲综合自在线| 国精产品一区一区三区有限公司| 久9re热视频这里只有精品| 交换交换乱杂烩系列yy| 女人19水真多免费毛片| 久久www免费人成一看片 | 国产日本精品视频在线观看| 国产精品专区免费观看软件 | 日本真人边吃奶边做爽动态图 | 97久久国产亚洲精品超碰热|