在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (GAPDHS), partial

In Stock
  • 中文名稱:
    人GAPDHS重組蛋白
  • 貨號:
    CSB-BP009254HU
  • 規格:
    ¥2832
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    GAPDHS
  • Uniprot No.:
  • 別名:
    G3PT_HUMAN; GAPD2; GAPDH 2 ; GAPDH-2; GAPDH2; GAPDHS; GAPDS; Glyceraldehyde 3 phosphate dehydrogenase spermatogenic; Glyceraldehyde 3 phosphate dehydrogenase; testis specific; Glyceraldehyde-3-phosphate dehydrogenase; HSD 35; HSD35; Spermatogenic cell specific glyceraldehyde 3 phosphate dehydrogenase 2; Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde 3 phosphate dehydrogenase; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase; testis-specific
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Baculovirus
  • 分子量:
    39.1 kDa
  • 表達區域:
    69-408aa
  • 氨基酸序列
    MVSVARELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRDK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility.
  • 基因功能參考文獻:
    1. GAPDS overexpression antagonize high glucose-induced apoptosis by controlling reactive oxygen species accumulation in TM3 cells. PMID: 29626473
    2. It is assumed that the deficiency in GAPDS observed in most dysplasia of the fibrous sheath sperm samples is ascribable to a disorder in the regulation of GAPDS expression caused by the mutation in the intron region of GAPDS gene. PMID: 27135296
    3. This result implies that GAPDHS participates in specific signal-transduction pathways. PMID: 26660717
    4. Structural basis for the NAD binding cooperativity and catalytic characteristics of sperm-specific glyceraldehyde-3-phosphate dehydrogenase PMID: 25936797
    5. GAPDS protein was expressed in both Sertoli cells and elongated sperms. The expression of GAPDS gradually increased with age in the epididymis. PMID: 23306140
    6. Data indicate that the positive expression of studied genes fertilization rate for GAPDHS positive subset was 66%, ACR - 71%, SPATA22 - 68%, MND1 - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively. PMID: 23675907
    7. the expression of GAPDS in melanoma cells may facilitate glycolysis and prevent the induction of apoptosis. PMID: 23026046
    8. The chaperonin TRiC was shown to assist an ATP-dependent refolding of recombinant forms of GAPDS. PMID: 21995946
    9. Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS. PMID: 21269272
    10. Human his-GAPDHS expressed in baculovirus-infected insect cells is homotetrameric. PMID: 20828617
    11. Data suggest that high stability of the sperm-specific GAPDS is of importance for the efficiency of fertilization. PMID: 20833277
    12. We have concluded that a simple nuclear localization of GAPDH does not induce apoptosis, and that MPP+-induced apoptosis is not caused by nuclear translocation of GAPDH. PMID: 16324157
    13. Comparative study of the amino acid sequences of mammalian GAPDs revealed conservative cysteine residues (C21, C94, and C150) that are specific for the sperm isoenzyme and absent in the somatic isoenzyme. PMID: 18298375
    14. Characterization of the rat GAPDHS and comparison to the human and mouse enzymes. PMID: 16700075
    15. GAPD2 enzymatic activity is present in human sperm. GAPD2 is tightly bound to sperm and most enzymatic activity is not released by permeabilization with CHAPS detergent. GAPD2 is restricted in location to the principal piece of the sperm flagellum. PMID: 10714828

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Glyceraldehyde-3-phosphate dehydrogenase family
  • 組織特異性:
    Testis specific.
  • 數據庫鏈接:

    HGNC: 24864

    OMIM: 609169

    KEGG: hsa:26330

    STRING: 9606.ENSP00000222286

    UniGene: Hs.248017



主站蜘蛛池模板: 精品视频在线观自拍自拍| 国产精品宾馆精品酒店| 亚洲综合狠狠丁香五月| 国产精品美女久久久久久福利| 正在播放国产真实露脸高清| 人妻少妇中文字幕久久| 国产乱妇乱子在线播放视频| 高潮毛片无遮挡高清免费视频| 国产裸体歌舞一区二区| 又色又爽又黄18禁美女裸身无遮挡| 国内精品国产三级国产av| 性夜影院午夜看片| 国产成熟女人性满足视频| 久久精品久久久久观看99水蜜桃| 亚洲熟熟妇xxxx| 久久激情日本亚洲欧洲国产中文 | 狠狠色丁香婷婷综合| 国产成人精品无码一区二区三区| 国产99视频精品免费视看6| 久久人人爽天天玩人人妻精品 | 精品无码一区二区三区在线| 男女免费观看做爰视频在线观看| 国产精品aⅴ在线观看| 人体内射精一区二区三区| 精品久久久久久久久久中文字幕| 久久精品人妻无码一区二区三区v 国产薄丝脚交视频在线观看 | 丰满人妻熟妇乱又伦精品视| 高清不卡毛片免费观看| 欧美天天拍在线视频| 久久婷婷五月综合97色一本一本 | 久久精品日日躁夜夜躁欧美| 国产女人叫床高潮大片| 国产精品丝袜黑色高跟鞋| 国产真实露脸乱子伦原著| 老司机午夜精品视频资源| 国产顶级熟妇高潮xxxxx| 亚洲伊人色欲综合网| 色天使亚洲综合一区二区| 国产高清在线精品一区免费| 国产精品久久久久久一区二区三区| 又黄又硬又湿又刺激视频免费|