在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (GAPDHS), partial

In Stock
  • 中文名稱:
    人GAPDHS重組蛋白
  • 貨號:
    CSB-BP009254HU
  • 規格:
    ¥2832
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    GAPDHS
  • Uniprot No.:
  • 別名:
    G3PT_HUMAN; GAPD2; GAPDH 2 ; GAPDH-2; GAPDH2; GAPDHS; GAPDS; Glyceraldehyde 3 phosphate dehydrogenase spermatogenic; Glyceraldehyde 3 phosphate dehydrogenase; testis specific; Glyceraldehyde-3-phosphate dehydrogenase; HSD 35; HSD35; Spermatogenic cell specific glyceraldehyde 3 phosphate dehydrogenase 2; Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde 3 phosphate dehydrogenase; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase; testis-specific
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Baculovirus
  • 分子量:
    39.1 kDa
  • 表達區域:
    69-408aa
  • 氨基酸序列
    MVSVARELTVGINGFGRIGRLVLRACMEKGVKVVAVNDPFIDPEYMVYMFKYDSTHGRYKGSVEFRNGQLVVDNHEISVYQCKEPKQIPWRAVGSPYVVESTGVYLSIQAASDHISAGAQRVVISAPSPDAPMFVMGVNENDYNPGSMNIVSNASCTTNCLAPLAKVIHERFGIVEGLMTTVHSYTATQKTVDGPSRKAWRDGRGAHQNIIPASTGAAKAVTKVIPELKGKLTGMAFRVPTPDVSVVDLTCRLAQPAPYSAIKEAVKAAAKGPMAGILAYTEDEVVSTDFLGDTHSSIFDAKAGIALNDNFVKLISWYDNEYGYSHRVVDLLRYMFSRDK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility.
  • 基因功能參考文獻:
    1. GAPDS overexpression antagonize high glucose-induced apoptosis by controlling reactive oxygen species accumulation in TM3 cells. PMID: 29626473
    2. It is assumed that the deficiency in GAPDS observed in most dysplasia of the fibrous sheath sperm samples is ascribable to a disorder in the regulation of GAPDS expression caused by the mutation in the intron region of GAPDS gene. PMID: 27135296
    3. This result implies that GAPDHS participates in specific signal-transduction pathways. PMID: 26660717
    4. Structural basis for the NAD binding cooperativity and catalytic characteristics of sperm-specific glyceraldehyde-3-phosphate dehydrogenase PMID: 25936797
    5. GAPDS protein was expressed in both Sertoli cells and elongated sperms. The expression of GAPDS gradually increased with age in the epididymis. PMID: 23306140
    6. Data indicate that the positive expression of studied genes fertilization rate for GAPDHS positive subset was 66%, ACR - 71%, SPATA22 - 68%, MND1 - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively. PMID: 23675907
    7. the expression of GAPDS in melanoma cells may facilitate glycolysis and prevent the induction of apoptosis. PMID: 23026046
    8. The chaperonin TRiC was shown to assist an ATP-dependent refolding of recombinant forms of GAPDS. PMID: 21995946
    9. Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS. PMID: 21269272
    10. Human his-GAPDHS expressed in baculovirus-infected insect cells is homotetrameric. PMID: 20828617
    11. Data suggest that high stability of the sperm-specific GAPDS is of importance for the efficiency of fertilization. PMID: 20833277
    12. We have concluded that a simple nuclear localization of GAPDH does not induce apoptosis, and that MPP+-induced apoptosis is not caused by nuclear translocation of GAPDH. PMID: 16324157
    13. Comparative study of the amino acid sequences of mammalian GAPDs revealed conservative cysteine residues (C21, C94, and C150) that are specific for the sperm isoenzyme and absent in the somatic isoenzyme. PMID: 18298375
    14. Characterization of the rat GAPDHS and comparison to the human and mouse enzymes. PMID: 16700075
    15. GAPD2 enzymatic activity is present in human sperm. GAPD2 is tightly bound to sperm and most enzymatic activity is not released by permeabilization with CHAPS detergent. GAPD2 is restricted in location to the principal piece of the sperm flagellum. PMID: 10714828

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Glyceraldehyde-3-phosphate dehydrogenase family
  • 組織特異性:
    Testis specific.
  • 數據庫鏈接:

    HGNC: 24864

    OMIM: 609169

    KEGG: hsa:26330

    STRING: 9606.ENSP00000222286

    UniGene: Hs.248017



主站蜘蛛池模板: 中文字幕无码乱码人妻系列蜜桃| 亚洲色中文字幕在线播放| 伊人婷婷六月狠狠狠去| 国产精品亚洲综合色区韩国| 色窝窝免费一区二区三区| 国产成人精品三上悠亚| 午夜福利视频合集1000| 久久国产乱子伦精品免费女人| 久久被窝亚洲精品爽爽爽| 内射白浆一区二区在线观看| 精品久久亚洲中文无码| 在线精品动漫一区二区无码| 免费午夜理论不卡| 色欧美片视频在线观看| 美女网站免费观看视频| 黑人巨茎大战欧美白妇| 国精品午夜福利视频| 成人亚洲欧美激情在线电影| 吸咬奶头狂揉60分钟视频| 18禁止进入1000部高潮网站| 欧美日本亚洲韩国一区| 国产乱了伦视频大全亚琴影院| 人人妻人人澡人人爽不卡视频| 亚洲国产天堂久久综合| 中文字幕在线亚洲日韩6页 | 亚洲国产三级在线观看| 少妇太爽了在线观看| 亚洲精品国精品久久99热| 狠狠色老熟妇老熟女| 午夜不卡无码中文字幕影院| 女人大荫蒂毛茸茸视频| 亚洲国产精品一区二区第四页 | 免费人成网视频在线观看| 一卡二卡3卡四卡网站精品| 亚洲va国产va天堂va久久| 国产在线一卡2卡三卡4卡免费| 亚洲中文字慕日产2021| 国产精品毛多多水多| 美女高潮黄又色高清视频免费| 久久久水蜜桃国产成人网站| 四库影院永久四虎精品国产|