在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3), partial

Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (B3GAT3), partial

  • 中文名稱：
    Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3(B3GAT3),partial
  • 貨號：
    CSB-YP002498HU1
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3(B3GAT3),partial
  • 貨號：
    CSB-EP002498HU1
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3(B3GAT3),partial
  • 貨號：
    CSB-EP002498HU1-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3(B3GAT3),partial
  • 貨號：
    CSB-BP002498HU1
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3(B3GAT3),partial
  • 貨號：
    CSB-MP002498HU1
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    B3GAT3
  • Uniprot No.：
  • 別名：
    B3GAT3; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3; Beta-1,3-glucuronyltransferase 3; Glucuronosyltransferase I; GlcAT-I; UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase; GlcUAT-I
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Glycosaminoglycans biosynthesis. Involved in forming the linkage tetrasaccharide present in heparan sulfate and chondroitin sulfate. Transfers a glucuronic acid moiety from the uridine diphosphate-glucuronic acid (UDP-GlcUA) to the common linkage region trisaccharide Gal-beta-1,3-Gal-beta-1,4-Xyl covalently bound to a Ser residue at the glycosaminylglycan attachment site of proteoglycans. Can also play a role in the biosynthesis of l2/HNK-1 carbohydrate epitope on glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates including Galbeta1-3Gal beta1-O-benzyl, Galbeta1-4GlcNAc and Galbeta1-4Glc. Stimulates 2-phosphoxylose phosphatase activity of PXYLP1 in presence of uridine diphosphate-glucuronic acid (UDP-GlcUA) during completion of linkage region formation.
  • 基因功能參考文獻(xiàn)：
    1. We identified a novel B3GAT3-related disorder with craniosynostosis and bone fragility, due to a unique homozygous mutation in B3GAT3. This syndrome should be considered in the prenatal period in light of the severe outcome and as an alternative diagnosis to Antley-Bixler or Shprintzen-Goldberg syndrome. PMID: 28771243
    2. Since the phenotype of the Nias patients differs from the Larsen-like syndrome described for patients with mutation p.(Arg277Gln), we suggest mutation B3GAT3:p.(Pro140Leu) to cause a different type of GAG linkeropathy showing no involvement of the heart. PMID: 25893793
    3. Reduced GlcAT-I activity impairs skeletal as well as heart development and results in variable combinations of heart malformations. PMID: 21763480
    4. functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif PMID: 12794088
    5. we evaluated the consequences of C-4/C-6 sulfation of Galbeta1-3Gal (Gal2-Gal1) on the activity and specificity of beta1,3-glucuronosyltransferase I PMID: 15522873
    6. GlcAT-I has a role in controlling and reversing articular cartilage defects PMID: 15601778
    7. A comparison of substrate specificity of beta1,3-glucuronosyltransferases revealed that GlcAT-I was selective toward Galbeta1,3Gal, whereas GlcAT-P presented a broader profile. PMID: 17567734
    8. 2-o-phosphorylation of xylose and 6-o-sulfation of galactose in the protein linkage region of glycosaminoglycans influence the glucuronyltransferase-I activity involved in the linkage region synthesis PMID: 18400750

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Multiple joint dislocations, short stature, and craniofacial dysmorphism with or without congenital heart defects (JDSCD)
  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein. Golgi apparatus, cis-Golgi network.
  • 蛋白家族：
    Glycosyltransferase 43 family
  • 組織特異性：
    Ubiquitous (but weakly expressed in all tissues examined).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 923

    OMIM: 245600

    KEGG: hsa:26229

    STRING: 9606.ENSP00000265471

    UniGene: Hs.502759



主站蜘蛛池模板： 久久精品无码免费不卡| 亚洲 欧美 国产 日韩 中文字幕| 欧美性大战久久久久久| 亚洲综合色在线视频www| 伊人成伊人成综合网222| 欧美三级在线播放线观看| 性色做爰片在线观看ww| 影音先锋男人站| 久久国内精品自在自线观看| 午夜无码成人免费视频| 亚洲va国产va天堂va久久| 婷婷色婷婷开心五月| 久久99精品久久久久久清纯| 又大又紧又粉嫩18p少妇| 美女张开腿黄网站免费| 国产精品高清不卡在线播放| 亚洲va中文字幕无码久久不卡| 国产精品久久久久久久久久免费看| 久久人搡人人玩人妻精品首页| 亚洲色成人网站www永久蜜芽| 日日大香人伊一本线久| 精品亚洲欧美无人区乱码| 九色九九九老阿姨| 人妻天天爽夜夜爽精品视频| 亚洲va中文字幕无码一二三区| 高清不卡一区二区三区| 欧美熟妇性开放| 亚洲综合无码一区二区三区不卡| 国内自拍五区| 大学生高潮无套内谢视频| 欧美乱码伦视频免费| 日亚韩在线无码一区二区三区| 免费久久99精品国产自在现线| av无码东京热亚洲男人的天堂| 亚洲sm另类一区二区三区| 国产偷窥熟妇高潮呻吟| 西西人体444www大胆无码视频 | 日韩精品人妻中文字幕有码| 人人爽人人爽人人片av免费| 亚洲欧洲日韩综合久久| 性色av免费观看|