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  4. Recombinant Human GTPase IMAP family member 4 (GIMAP4)

Recombinant Human GTPase IMAP family member 4 (GIMAP4)

  • 中文名稱：
    人GIMAP4重組蛋白
  • 貨號：
    CSB-YP885732HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GIMAP4重組蛋白
  • 貨號：
    CSB-EP885732HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GIMAP4重組蛋白
  • 貨號：
    CSB-EP885732HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GIMAP4重組蛋白
  • 貨號：
    CSB-BP885732HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GIMAP4重組蛋白
  • 貨號：
    CSB-MP885732HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GIMAP4
  • Uniprot No.：
  • 別名：
    FLJ11110; GIMA4_HUMAN; Gimap4; GTPase IMAP family member 4 ; GTPase IMAP family member 4; hIAN1; HIMAP4 ; Human immune associated nucleotide 1; IAN-1; IAN1 ; IMAP4 ; Immunity associated nucleotide 1 protein; Immunity associated protein 4; Immunity-associated nucleotide 1 protein; Immunity-associated protein 4; MSTP062
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-329
  • 氨基酸序列
    MAAQYGSMSF NPSTPGASYG PGRQEPRNSQ LRIVLVGKTG AGKSATGNSI LGRKVFHSGT AAKSITKKCE KRSSSWKETE LVVVDTPGIF DTEVPNAETS KEIIRCILLT SPGPHALLLV VPLGRYTEEE HKATEKILKM FGERARSFMI LIFTRKDDLG DTNLHDYLRE APEDIQDLMD IFGDRYCALN NKATGAEQEA QRAQLLGLIQ RVVRENKEGC YTNRMYQRAE EEIQKQTQAM QELHRVELER EKARIREEYE EKIRKLEDKV EQEKRKKQME KKLAEQEAHY AVRQQRARTE VESKDGILEL IMTALQIASF ILLRLFAED
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    During thymocyte development, may play a role in the regulation of apoptosis. GTPase which exhibits a higher affinity for GDP than for GTP.
  • 基因功能參考文獻：
    1. GIMAP4 regulates secretion of cytokines in early differentiating human CD4(+) T helper lymphocytes and in particular the secretion of interferon-gamma also affecting its downstream targets. PMID: 25287446
    2. Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease PMID: 23041938
    3. molecular and genetic properties; expression in resting T- and B-cells and decreased expression during lymphocyte activation PMID: 11964296
    4. GIMAP1 and GIMAP4 genes are up-regulated by IL-12 and other Th1 differentiation-inducing cytokines in cells induced to differentiate toward Th1 lineage and down-regulated by IL-4 in cells induced to Th2. PMID: 18701445
  • 亞細胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily
  • 組織特異性：
    Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower lev
  • 數據庫鏈接：

    HGNC: 21872

    OMIM: 608087

    KEGG: hsa:55303

    STRING: 9606.ENSP00000255945

    UniGene: Hs.647101



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