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GIMAP4 Antibody

  • 中文名稱:
    GIMAP4兔多克隆抗體
  • 貨號:
    CSB-PA002681
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of RAW264.7 cells using GIMAP4 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GIMAP4
  • 別名:
    FLJ11110 antibody; GIMA4_HUMAN antibody; Gimap4 antibody; GTPase IMAP family member 4 antibody; GTPase IMAP family member 4 antibody; hIAN1 antibody; HIMAP4 antibody; Human immune associated nucleotide 1 antibody; IAN-1 antibody; IAN1 antibody; IMAP4 antibody; Immunity associated nucleotide 1 protein antibody; Immunity associated protein 4 antibody; Immunity-associated nucleotide 1 protein antibody; Immunity-associated protein 4 antibody; MSTP062 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GIMAP4.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    During thymocyte development, may play a role in the regulation of apoptosis. GTPase which exhibits a higher affinity for GDP than for GTP.
  • 基因功能參考文獻:
    1. GIMAP4 regulates secretion of cytokines in early differentiating human CD4(+) T helper lymphocytes and in particular the secretion of interferon-gamma also affecting its downstream targets. PMID: 25287446
    2. Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behcet's disease PMID: 23041938
    3. molecular and genetic properties; expression in resting T- and B-cells and decreased expression during lymphocyte activation PMID: 11964296
    4. GIMAP1 and GIMAP4 genes are up-regulated by IL-12 and other Th1 differentiation-inducing cytokines in cells induced to differentiate toward Th1 lineage and down-regulated by IL-4 in cells induced to Th2. PMID: 18701445
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily
  • 組織特異性:
    Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower lev
  • 數據庫鏈接:

    HGNC: 21872

    OMIM: 608087

    KEGG: hsa:55303

    STRING: 9606.ENSP00000255945

    UniGene: Hs.647101



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