在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Fibroblast growth factor receptor-like 1 (FGFRL1), partial

Recombinant Human Fibroblast growth factor receptor-like 1 (FGFRL1), partial

  • 中文名稱：
    人FGFRL1重組蛋白
  • 貨號：
    CSB-YP008650HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人FGFRL1重組蛋白
  • 貨號：
    CSB-EP008650HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人FGFRL1重組蛋白
  • 貨號：
    CSB-EP008650HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人FGFRL1重組蛋白
  • 貨號：
    CSB-BP008650HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人FGFRL1重組蛋白
  • 貨號：
    CSB-MP008650HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FGFRL1
  • Uniprot No.：
  • 別名：
    FGF homologous factor receptor; FGF receptor like protein 1; FGF receptor-like protein 1; FGFR 5; FGFR like protein; FGFR-5; FGFR-like protein; FGFR5; Fgfrl1; FGRL1_HUMAN; FHFR; Fibroblast growth factor receptor 5; Fibroblast growth factor receptor like 1; Fibroblast growth factor receptor-like 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Has a negative effect on cell proliferation.
  • 基因功能參考文獻：
    1. this study shows FGFRL1 promotes ovarian cancer progression by crosstalk with Hedgehog signaling PMID: 29675438
    2. FGFRL1 is a transmembrane receptor that can induce the fusion of CHO cells to multinucleated syncytia. This cell fusion activity has been attributed to the extracellular Ig3 domain of the receptor. The Ig3 domain from humans, mice, chicken and fish stimulates fusion of CHO cells, while the Ig3 domain from lancelet and sea urchin does not. PMID: 28596102
    3. Both in vitro and in vivo studies determined that miR-210 promoted hepatocellular carcinoma (HCC), angiogenesis, and the corresponding mechanism was identified to be the direct targeting and inhibition of fibroblast growth factor receptor-like 1 (FGFRL1) expression PMID: 27666683
    4. FGFRL1 is a cell adhesion protein. PMID: 27220341
    5. functional evidence for a novel FGFRL1 poly-miRTS rs4647940 in a previously known 4p16.3 locus, and experimental and clinical genetics studies have shown both FGFRL1 and hsa-miR-140-5p are important for bone formation. PMID: 25941324
    6. Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 PMID: 26025674
    7. The signaling complex appears to integrate the input from FGFR and EphA4, and release the output signal through FRS2alpha. PMID: 20184660
    8. study identified a novel region of deletion mapping to 4p16.3 in 15 percent of bladder tumors and 24 percent of bladder cancer cell lines; FGFRL1, which maps within this region, was investigated as putative deletion target; average FGFRL1 protein expression was lower in bladder tumors compared to normal tissue, but downregulation was independent from 4p16.3 LOH status PMID: 23775577
    9. Interaction of FGFRL1 with Spred1 increases the proportion of the receptor at the plasma membrane. PMID: 21616146
    10. an important role for miR-210 as a tumor-suppressive microRNA with effects on cancer cell proliferation PMID: 21044961
    11. FGFRL1 is capable of inducing syncytium formation of heterologous cells in vitro. PMID: 20851884
    12. FGFRL1 is indeed a decoy receptor for FGFs. PMID: 19920134
    13. analysis of FGF18 and FGFR5(FGFRL1) expression in primary endothelial cells and vascular smooth muscle cells PMID: 16019430
    14. Screening of 241 different human tumors with the help of a cancer profiling array suggested major alterations in the relative expression of FGFRL1 in ovarian tumors PMID: 16273302
    15. The extracellular domain of recombinant FGFRL1 promoted cell adhesion, but not cell spreading. Adhesion was mediated by heparan sulfate glycosaminoglycans located at the cell surface. PMID: 18061161
    16. mutant FGFRL1 contributes to the skeletal malformations of the patient PMID: 19056490

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.
  • 組織特異性：
    Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen.
  • 數據庫鏈接：

    HGNC: 3693

    OMIM: 605830

    KEGG: hsa:53834

    STRING: 9606.ENSP00000264748

    UniGene: Hs.193326



主站蜘蛛池模板： 国产精品99久久不卡| 免费吃奶摸下激烈视频| 中文字幕无码一区二区免费| 国产寡妇偷人在线观看| 国产成人免费永久播放视频平台| 久久精品一区二区av999| 97碰碰碰人妻无码视频| 高清精品一区二区三区| 久久精品成人免费观看| 日韩亚洲国产激情一区浪潮av| 国产999精品成人网站| 日本一区二区更新不卡| 先锋影音av资源站av| 丰满少妇熟女高潮流白浆| 动漫av网站免费观看| 欧美变态另类xxxx| 青青久久成人免费影院| 伊人久久大香线蕉综合75| 美女内射毛片在线看免费人动物| 日韩国产亚洲欧美中国v| 成人免费无码视频在线网站| 精品人妻系列无码一区二区三区| 亚洲h在线播放在线观看h| 国产在热线精品视频99公交| 亚洲成年看片在线观看| 国产精品国产高清国产av| 色婷婷综合久久久久中文一区二区 | 无码人妻精品中文字幕| 国产亚洲一卡2卡3卡4卡网站| 欧美日韩无线码在线观看| 日韩欧美猛交xxxxx无码| 亚洲精品国产福利一区二区| 亚洲精品av一区在线观看| 国产av无码国产av毛片| 51久久成人国产精品麻豆| 天天躁久久躁日日躁| 国产又黄又爽又色的免费视频| 天天噜日日噜狠狠噜免费| 国产精品麻豆成人av网| 亚洲精品久久久久久久蜜桃臀| 国精产品一区一区三区有限公司杨|