在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FGFRL1 Antibody

FGFRL1 Antibody

  • 中文名稱：
    FGFRL1兔多克隆抗體
  • 貨號：
    CSB-PA008650LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA008650LA01HU diluted at 1:500 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA008650LA01HU diluted at 1:500 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA008650LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FGFRL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FGFRL1
  • 別名：
    FGF homologous factor receptor antibody; FGF receptor like protein 1 antibody; FGF receptor-like protein 1 antibody; FGFR 5 antibody; FGFR like protein antibody; FGFR-5 antibody; FGFR-like protein antibody; FGFR5 antibody; Fgfrl1 antibody; FGRL1_HUMAN antibody; FHFR antibody; Fibroblast growth factor receptor 5 antibody; Fibroblast growth factor receptor like 1 antibody; Fibroblast growth factor receptor-like 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Fibroblast growth factor receptor-like 1 protein (403-470AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，FGFRL1 Antibody (CSB-PA008650LA01HU)，的標記方式是Non-conjugated。對于FGFRL1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA008650LB01HU FGFRL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA008650LC01HU FGFRL1 Antibody, FITC conjugated
    Biotin CSB-PA008650LD01HU FGFRL1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:500-1:1000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Has a negative effect on cell proliferation.
  • 基因功能參考文獻：
    1. this study shows FGFRL1 promotes ovarian cancer progression by crosstalk with Hedgehog signaling PMID: 29675438
    2. FGFRL1 is a transmembrane receptor that can induce the fusion of CHO cells to multinucleated syncytia. This cell fusion activity has been attributed to the extracellular Ig3 domain of the receptor. The Ig3 domain from humans, mice, chicken and fish stimulates fusion of CHO cells, while the Ig3 domain from lancelet and sea urchin does not. PMID: 28596102
    3. Both in vitro and in vivo studies determined that miR-210 promoted hepatocellular carcinoma (HCC), angiogenesis, and the corresponding mechanism was identified to be the direct targeting and inhibition of fibroblast growth factor receptor-like 1 (FGFRL1) expression PMID: 27666683
    4. FGFRL1 is a cell adhesion protein. PMID: 27220341
    5. functional evidence for a novel FGFRL1 poly-miRTS rs4647940 in a previously known 4p16.3 locus, and experimental and clinical genetics studies have shown both FGFRL1 and hsa-miR-140-5p are important for bone formation. PMID: 25941324
    6. Cell-cell fusion induced by the Ig3 domain of receptor FGFRL1 PMID: 26025674
    7. The signaling complex appears to integrate the input from FGFR and EphA4, and release the output signal through FRS2alpha. PMID: 20184660
    8. study identified a novel region of deletion mapping to 4p16.3 in 15 percent of bladder tumors and 24 percent of bladder cancer cell lines; FGFRL1, which maps within this region, was investigated as putative deletion target; average FGFRL1 protein expression was lower in bladder tumors compared to normal tissue, but downregulation was independent from 4p16.3 LOH status PMID: 23775577
    9. Interaction of FGFRL1 with Spred1 increases the proportion of the receptor at the plasma membrane. PMID: 21616146
    10. an important role for miR-210 as a tumor-suppressive microRNA with effects on cancer cell proliferation PMID: 21044961
    11. FGFRL1 is capable of inducing syncytium formation of heterologous cells in vitro. PMID: 20851884
    12. FGFRL1 is indeed a decoy receptor for FGFs. PMID: 19920134
    13. analysis of FGF18 and FGFR5(FGFRL1) expression in primary endothelial cells and vascular smooth muscle cells PMID: 16019430
    14. Screening of 241 different human tumors with the help of a cancer profiling array suggested major alterations in the relative expression of FGFRL1 in ovarian tumors PMID: 16273302
    15. The extracellular domain of recombinant FGFRL1 promoted cell adhesion, but not cell spreading. Adhesion was mediated by heparan sulfate glycosaminoglycans located at the cell surface. PMID: 18061161
    16. mutant FGFRL1 contributes to the skeletal malformations of the patient PMID: 19056490

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles.
  • 組織特異性：
    Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen.
  • 數據庫鏈接：

    HGNC: 3693

    OMIM: 605830

    KEGG: hsa:53834

    STRING: 9606.ENSP00000264748

    UniGene: Hs.193326



主站蜘蛛池模板： 国产女人抽搐喷浆视频| 四虎影视在线影院在线观看免费视频| 精人妻无码一区二区三区| 福利姬液液酱喷水| 国产精品久久久久av| 午夜伦yy44880影院| 风韵人妻丰满熟妇老熟女| 国产巨大爆乳在线观看| 久久只有这里有精品4| 丰满少妇熟女高潮流白浆| 久久久精品日本一区二区三区| 夜夜国产亚洲视频香蕉| 99在线精品免费视频九九视| 一本天堂v无码亚洲道久久| 爆乳喷奶水无码正在播放| 欧美性黑人极品hd| 怡红院a∨人人爰人人爽| 好吊妞无缓冲视频观看| 国产aⅴ精品一区二区三区尤物| 亚洲精品无码久久久久av老牛| 欧美白丰满老太aaa片| 国产suv精品一区二区33| 脱岳裙子从后面挺进去在线观看| 色天天天综合色天天| 12裸体自慰免费观看网站| 18禁黄久久久aaa片| 国产偷v国产偷v亚洲高清| 一本色道久久hezyo无码| 亚洲中文字幕精品久久久久久动漫| 男人的天堂av社区在线| 人成午夜免费视频无码| 日本50岁丰满熟妇xxxx| 女人被狂躁到高潮视频免费软件 | 成人国产一区二区三区精品| 亚洲人成亚洲人成在线观看| 亚洲日本中文字幕天天更新| 99久久国产自偷自偷免费一区| 国产精品美女乱子伦高潮| 粗大的内捧猛烈进出在线视频| а√8天堂中文官网资源| 亚洲国产美国国产综合一区|