在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human FXYD domain-containing ion transport regulator 3 (FXYD3), partial

Recombinant Human FXYD domain-containing ion transport regulator 3 (FXYD3), partial

  • 中文名稱：
    人FXYD3重組蛋白
  • 貨號：
    CSB-YP622789HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人FXYD3重組蛋白
  • 貨號：
    CSB-EP622789HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人FXYD3重組蛋白
  • 貨號：
    CSB-BP622789HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人FXYD3重組蛋白
  • 貨號：
    CSB-MP622789HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    FXYD3
  • Uniprot No.：
  • 別名：
    Chloride conductance inducer protein Mat 8; Chloride conductance inducer protein Mat-8; FXYD domain containing ion transport regulator 3; FXYD domain-containing ion transport regulator 3; Fxyd3; FXYD3_HUMAN; Mammary tumor 8 kDa protein; MAT-8; MAT8; MGC111076; Phospholemman like; Phospholemman-like; PLML
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes.; Decreases the apparent K+ and Na+ affinity of the sodium/potassium-transporting ATPase over a large range of membrane potentials.; Decreases the apparent K+ affinity of the sodium/potassium-transporting ATPase only at slightly negative and positive membrane potentials and increases the apparent Na+ affinity over a large range of membrane potentials.
  • 基因功能參考文獻：
    1. Suppression of FXYD3 in MCF-7. PMID: 26740212
    2. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (p = 0.0110), S100A11 (p = 0.0071), and GSTM3 (p = 0.0173) in colon cancer lymphatic metastasis. PMID: 22430872
    3. ExoS facilitates P. aeruginosa penetration through the intestinal epithelial barrier by binding to FXYD3 and thereby impairing the defense function of tight junctions against bacterial penetration. PMID: 20805335
    4. Up-regulated expression of FXYD-3 protein may be involved in tumourgenesis and invasion of gastric adenocarcinoma. PMID: 20364041
    5. FXYD3 expression is related to several biological variables including ras, p53, legumain and PCNA, and may be involved in the development of the relatively early stages of colorectal cancers PMID: 19955746
    6. Upregulation of FXYD3 is associated with glioma. PMID: 20112499
    7. inactivation of FXYD3 through a gene mutation or unknown mechanism could be one cause of the atypical shapes of cancer cells and play a potential role in the progression of lung cancer. PMID: 19893046
    8. Results indicate that the human MAT-8 gene contains the potential to serve as a prostate cancer expression marker and that MAT-8 plays an important role in cellular growth of prostate carcinomas. PMID: 14654946
    9. overexpression of FXYD3 in pancreatic cancer may contribute to the proliferative activity of this malignancy PMID: 16003754
    10. analysis of two human FXYD3 isoforms that are differentially expressed in differentiated and non-differentiated cells with different functional properties PMID: 17077088
    11. FXYD3 interacts with Na(+)-K(+)-Exchanging ATPase in colorectal neoplasms. PMID: 17409496
    12. structures of the FXYD proteins (with emphasis on 1-4), as well as their dynamics and their associations with the lipid PMID: 18000745
    13. FXYD3 silencing prevents proper regulation of Na,K-ATPase, which leads to perturbation of cellular Na+ and K+ homeostasis and changes in the expression of Na,K-ATPase isozymes, whose functional properties are incompatible with cell differentiation. PMID: 19109419
    14. FXYD3a protein is highly expressed in breast cancers, and responsible for cancer cell proliferation. PMID: 19571376

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    FXYD family
  • 組織特異性：
    Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level).
  • 數據庫鏈接：

    HGNC: 4027

    OMIM: 604996

    KEGG: hsa:5349

    STRING: 9606.ENSP00000389770

    UniGene: Hs.301350



主站蜘蛛池模板： 午夜熟女插插xx免费视频| 热99re久久精品天堂| 亚洲精品无码av中文字幕电影网站| 少妇爆乳无码专区网站| 中文无码日韩欧免费视频| av无码av天天av天天爽| 久久亚洲私人国产精品| 白丝乳交内射一二三区| 69国产精品成人aaaaa片| 99精品众筹模特自拍视频| 欧美xxxx黑人又粗又长精品| 免费国产午夜理论片不卡| 在教室伦流澡到高潮h麻豆| 中国娇小与黑人巨大交| 特级做a爰片毛片免费看108| 亚洲综合久久无码色噜噜赖水 | 日韩精品久久久肉伦网站| 国产美女爽到尿喷出来视频| 护士奶头又大又软又好摸| 国模冰莲自慰肥美胞极品人体图| 久久久久久久极品内射| 色欲久久综合亚洲精品蜜桃| 国产成人一区二区三区免费| 99久久精品无码一区二区三区| 鲁丝片一区二区三区毛片| 麻豆果冻精东九一传媒mv| 真实国产乱子伦对白在线播放| 国产一卡2卡3卡4卡网站精品| 久热在线中文字幕色999舞| 国产亚洲精品久久久久久国| 国产精品玩偶在线观看| 国产成人久久精品77777综合| 少妇午夜福利一区二区| 伊人狼人大焦香久久网| 国产啪精品视频网站| 中国女人内谢69xxxxxa片| 国产又黄又爽又色的免费| 精品亚洲国产成人av制服| 亚洲乱妇老熟女爽到高潮的片| 精产国品一二三产区蘑菇视频| 三级无码在钱av无码在钱|