在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human FK506-binding protein-like (FKBPL)

  • 中文名稱:
    人FKBPL重組蛋白
  • 貨號:
    CSB-EP883441HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    FKBPL
  • Uniprot No.:
  • 別名:
    DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL_HUMAN; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    65.2kDa
  • 表達區(qū)域:
    1-349aa
  • 氨基酸序列
    METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
  • 基因功能參考文獻:
    1. This study identified two low-frequency nonsynonymous variants at FKBPL (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and ARPC1B (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk. PMID: 27479355
    2. The data suggests a role for FKBPL as a prognostic factor for BCSS, with the potential to be routinely evaluated within the clinic. PMID: 25906750
    3. WISp39 preferentially interacts with phosphorylated Coronin 1B, allowing it to complex with Slingshot phosphatase to dephosphorylate and activate Cofilin. PMID: 25800056
    4. FKBPL is an important regulator of developmental and pathological angiogenesis. PMID: 25767277
    5. high levels of FKBPL and RBCK1 correlated with increased patient survival, whereas high RBCK1 predicted for a poor response to tamoxifen. PMID: 23912458
    6. FKBPL and and its peptide derivative, AD-01 regulate expression of CD44. PMID: 23457460
    7. Genome-wide association study of age-related macular degeneration identifies TNXB, FKBPL and NOTCH4 as candidate susceptibility genes. PMID: 22694956
    8. Alterations in the gene for FKBPL in azoospermic patients. PMID: 20210997
    9. Findings suggest that FKBPL may have prognostic value based on its impact on tumor proliferative capacity and sensitivity to endocrine therapies, which improve outcome. PMID: 20103631
    10. Results demonstrate the importance of posttranslational stabilization of p21 protein by WISp39 in regulating cellular p21 activity. PMID: 15664193
    11. FKBPL can be classed as a new member of the FKBP protein family with a role in steroid receptor complexes and signaling. PMID: 18669603

    顯示更多

    收起更多

  • 組織特異性:
    Ubiquitously expressed with higher levels in testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13949

    KEGG: hsa:63943

    STRING: 9606.ENSP00000364298

    UniGene: Hs.520042



主站蜘蛛池模板: 奶头好大狂揉60分钟视频| 水蜜桃精品一二三| a v 在线视频 亚洲免费| 三级全黄的视频在线观看| 高清不卡一区二区三区| 在线 | 一区二区三区| 最新国产精品好看的精品| 亚洲午夜高清国产拍| 精精国产xxxx视频在线| 精品无码一区二区三区不卡| 亚洲欧美自拍制服另类图区| 丰满少妇被猛烈进av毛片| 亚洲国产中文字幕在线视频综合| 日日躁夜夜躁狠狠躁| 亚洲综合精品成人| 99er热精品视频| 99久久国产露脸国语对白| 无码国产成人午夜视频在线播放| 无码福利在线观看1000集| 国产麻豆剧果冻传媒白晶晶| 漂亮人妻去按摩被按中出| 九九热线精品视频16| 国产乱码一区二区三区爽爽爽 | 国产老熟女伦老熟妇露脸| 波多野结衣av一区二区全免费观看| 狠狠色噜噜狠狠狠7777米奇| 成人av无码国产在线观看| 在线观看免费人成视频色9| 亚洲精品久久久久久成人| 国产精品亚洲二区在线看| 国产熟妇按摩3p高潮大叫| 婷婷成人丁香五月综合激情| 国产午睡沙发被弄醒完整版 | 天堂www天堂在线资源| 强行糟蹋人妻hd中文| 日韩乱码人妻无码系列中文字幕| 欧美另类又黄又爽的a片| 无码人妻丰满熟妇区96| 欧美亚洲国产成人一区二区三区 | 亚洲女人色综合小说| 欧美丰满熟妇bbb久久久|