在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human FK506-binding protein-like (FKBPL)

  • 中文名稱:
    人FKBPL重組蛋白
  • 貨號:
    CSB-EP883441HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    FKBPL
  • Uniprot No.:
  • 別名:
    DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL_HUMAN; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    65.2kDa
  • 表達區(qū)域:
    1-349aa
  • 氨基酸序列
    METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
  • 基因功能參考文獻:
    1. This study identified two low-frequency nonsynonymous variants at FKBPL (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and ARPC1B (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk. PMID: 27479355
    2. The data suggests a role for FKBPL as a prognostic factor for BCSS, with the potential to be routinely evaluated within the clinic. PMID: 25906750
    3. WISp39 preferentially interacts with phosphorylated Coronin 1B, allowing it to complex with Slingshot phosphatase to dephosphorylate and activate Cofilin. PMID: 25800056
    4. FKBPL is an important regulator of developmental and pathological angiogenesis. PMID: 25767277
    5. high levels of FKBPL and RBCK1 correlated with increased patient survival, whereas high RBCK1 predicted for a poor response to tamoxifen. PMID: 23912458
    6. FKBPL and and its peptide derivative, AD-01 regulate expression of CD44. PMID: 23457460
    7. Genome-wide association study of age-related macular degeneration identifies TNXB, FKBPL and NOTCH4 as candidate susceptibility genes. PMID: 22694956
    8. Alterations in the gene for FKBPL in azoospermic patients. PMID: 20210997
    9. Findings suggest that FKBPL may have prognostic value based on its impact on tumor proliferative capacity and sensitivity to endocrine therapies, which improve outcome. PMID: 20103631
    10. Results demonstrate the importance of posttranslational stabilization of p21 protein by WISp39 in regulating cellular p21 activity. PMID: 15664193
    11. FKBPL can be classed as a new member of the FKBP protein family with a role in steroid receptor complexes and signaling. PMID: 18669603

    顯示更多

    收起更多

  • 組織特異性:
    Ubiquitously expressed with higher levels in testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13949

    KEGG: hsa:63943

    STRING: 9606.ENSP00000364298

    UniGene: Hs.520042



主站蜘蛛池模板: 欧美内射深插日本少妇| 亚洲精品无码你懂的| 国产又黄又潮娇喘视频在线观看| 狠狠做久久深爱婷婷| 国产成人久久av免费| 久久精品国产99精品国产亚洲性色| 国产精品国产三级在线专区| 国产成人亚洲综合无码18禁h| 日韩内射美女片在线观看网站| 欧美丰满老熟妇乱叫| 中文字幕人妻无码一夲道| 一本色道久久综合无码人妻| 亚洲一区二区三区无码久久| 日本国产网曝视频在线观看 | 免费视频欧美无人区码| 激情偷乱人伦小说视频| 一边摸一边叫床一边爽av| 精品一区二区三区四区五区六区| 99re久久精品国产| 人人爽人人爽人人片av| 成人a片产无码免费视频在线观看| 免费无码又爽又刺激聊天app| 亚洲国产成人精品女人久久久| 亚洲最大的成人网站| 国产片a国产片免费看视频| 亚洲中文字幕无码日韩精品| 亚洲熟妇av乱码在线观看| 在线人人车操人人看视频| 日韩成人无码v清免费| 国产 | 欧洲野花视频天堂视频p| 男人j桶进女人p无遮挡免费观看| 久久国产精品精品国产色婷婷| 久久这里只精品国产免费9| 亚洲伊人久久精品酒店| 鲁大师在线视频播放免费观看| 麻豆文化传媒精品一区观看| 色老头精品午夜福利视频| 无码中文字幕乱在线观看| 日韩精品一区二区三区免费视频| 亚洲国产成人av片在线播放| 四虎永久在线精品免费无码|