在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human F-box/LRR-repeat protein 4 (FBXL4)

  • 中文名稱:
    人FBXL4重組蛋白
  • 貨號:
    CSB-YP891533HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人FBXL4重組蛋白
  • 貨號:
    CSB-EP891533HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人FBXL4重組蛋白
  • 貨號:
    CSB-EP891533HU-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人FBXL4重組蛋白
  • 貨號:
    CSB-BP891533HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人FBXL4重組蛋白
  • 貨號:
    CSB-MP891533HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    FBXL4
  • Uniprot No.:
  • 別名:
    FBXL4; FBL4; FBL5F-box/LRR-repeat protein 4; F-box and leucine-rich repeat protein 4; F-box protein FBL4/FBL5
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-621
  • 氨基酸序列
    MSPVFPMLTV LTMFYYICLR RRARTATRGE MMNTHRAIES NSQTSPLNAE VVQYAKEVVD FSSHYGSENS MSYTMWNLAG VPNVFPSSGD FTQTAVFRTY GTWWDQCPSA SLPFKRTPPN FQSQDYVELT FEQQVYPTAV HVLETYHPGA VIRILACSAN PYSPNPPAEV RWEILWSERP TKVNASQARQ FKPCIKQINF PTNLIRLEVN SSLLEYYTEL DAVVLHGVKD KPVLSLKTSL IDMNDIEDDA YAEKDGCGMD SLNKKFSSAV LGEGPNNGYF DKLPYELIQL ILNHLTLPDL CRLAQTCKLL SQHCCDPLQY IHLNLQPYWA KLDDTSLEFL QSRCTLVQWL NLSWTGNRGF ISVAGFSRFL KVCGSELVRL ELSCSHFLNE TCLEVISEMC PNLQALNLSS CDKLPPQAFN HIAKLCSLKR LVLYRTKVEQ TALLSILNFC SELQHLSLGS CVMIEDYDVI ASMIGAKCKK LRTLDLWRCK NITENGIAEL ASGCPLLEEL DLGWCPTLQS STGCFTRLAH QLPNLQKLFL TANRSVCDTD IDELACNCTR LQQLDILGTR MVSPASLRKL LESCKDLSLL DVSFCSQIDN RAVLELNASF PKVFIKKSFT Q
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻(xiàn):
    1. Biallelic pathogenic variants in FBXL4 are associated with an encephalopathic mtDNA maintenance defect syndrome that is a multisystem disease. PMID: 28940506
    2. Overall, FBXL4 defects account for at least 0.7% (6 out of 808) of subjects suspected to have a mitochondrial disorder, and as high as 14.3% (4 out of 28) in young children with congenital lactic acidosis and clinical features of mitochondrial disease. Including FBLX4 in the mitochondrial diseases panel should be particularly important for patients with congenital lactic acidosis PMID: 27743463
    3. On clinical indication of mitochondrial encephalomyopathy, sequencing of FBXL4 should be performed, even when the activity levels of the MRC enzymes are normal PMID: 27182039
    4. A clinical pattern of early-onset encephalopathy, persistent lactic acidosis, profound muscular hypotonia and typical facial dysmorphism should prompt initiation of molecular genetic analysis of FBXL4. PMID: 25868664
    5. Mutations in FBXL4 are disease causing and establish FBXL4 as a mitochondrial protein with a possible role in maintaining mtDNA integrity and stability. PMID: 23993193
    6. These data strongly support a role for FBXL4 in controlling bioenergetic homeostasis and mtDNA maintenance. PMID: 23993194
    7. SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein PMID: 21757720

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Mitochondrial DNA depletion syndrome 13 (MTDPS13)
  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Mitochondrion.
  • 組織特異性:
    Expressed in heart, kidney, liver, lung, pancreas, and placenta, but not in skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 13601

    OMIM: 605654

    KEGG: hsa:26235

    STRING: 9606.ENSP00000229971

    UniGene: Hs.536850



主站蜘蛛池模板: 国产成人亚洲综合色婷婷| 中出あ人妻熟女中文字幕| aaaaa少妇高潮大片| 伊人亚洲综合影院首页| 色综合视频一区中文字幕| 久久人妻xunleige无码| 无码人妻一区二区三区免费n鬼逝| 国产尤物精品自在拍视频首页| 扒开双腿疯狂进出爽爽爽视频| 日本视频高清一道一区| 日本三级韩国三级欧美三级| 动漫精品专区一区二区三区不卡| 日韩内射激情视频在线播放免费| 久久久综综合色一本伊人| 婷婷综合久久中文字幕| 久久久99精品免费观看| 国产精品福利自产拍在线观看| 国产午夜精品一区二区三区老| 九九热久久只有精品2| 狠狠做五月深爱婷婷伊人| 久久99亚洲精品久久99果| 免费午夜无码片在线观看影院| 天堂亚洲2017在线观看| 好硬好湿好爽再深一点动态图视频 | 在线精品国精品国产尤物| 午夜福利视频1692| 群交射精白浆视频| 久久国产劲爆∧v内射-百度| 人人妻人人爽人人澡欧美一区 | 亚洲中字幕日产av片在线| 狠狠色色综合网站| 国产成人精品一区二区三区视频| 7m精品福利视频导航| 久久www成人看片免费不卡| 亚洲伊人色欲综合网无码中文| 视频分类 国内精品| 国产成人无码a区在线观看导航| 久久精品国产福利一区二区| 国产亚洲熟妇综合视频| 99re久久精品国产首页| а√天堂www在线天堂小说|