在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Erlin-1 (ERLIN1), partial

Recombinant Human Erlin-1 (ERLIN1), partial

  • 中文名稱：
    人ERLIN1重組蛋白
  • 貨號：
    CSB-YP007790HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ERLIN1重組蛋白
  • 貨號：
    CSB-EP007790HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ERLIN1重組蛋白
  • 貨號：
    CSB-EP007790HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ERLIN1重組蛋白
  • 貨號：
    CSB-BP007790HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ERLIN1重組蛋白
  • 貨號：
    CSB-MP007790HU1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ERLIN1
  • Uniprot No.：
  • 別名：
    ERLIN1; C10orf69; KE04; KEO4; SPFH1; Erlin-1; Endoplasmic reticulum lipid raft-associated protein 1; Protein KE04; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; SPFH domain-containing protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.; (Microbial infection) Required early in hepatitis C virus (HCV) infection to initiate RNA replication, and later in the infection to support infectious virus production.
  • 基因功能參考文獻：
    1. Erlin-1 and the related erlin-2 were found to selectively bind cholesterol. Knockdown of the proteins by RNAi in cultured cells resulted in high levels of cholesterol and fatty acid biosynthesis in the presence of cholesterol sufficiency. PMID: 24217618
    2. Here we show that the multimeric ER proteins erlins-1 and -2 are additional sterol regulatory element binding protein regulators. PMID: 24217618
    3. Our findings suggest ERLIN1-CHUK-CWF19L1 variants are associated with early stage of fatty liver accumulation to hepatic inflammation. PMID: 23477746
    4. Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER. PMID: 16835267
    5. Results suggest that this novel SPFH1/2 complex is a recognition factor that targets IP(3)Rs and perhaps other substrates for ERAD. PMID: 19240031
    6. m3 receptor-expressing HeLa cells are a valuable system for studying IP(3) receptor ERAD, and suggest that the SPFH1/2 complex is a factor that selectively mediates the ERAD of activated IP(3) receptors. PMID: 19751772

    顯示更多

    收起更多

  • 相關疾病：
    Spastic paraplegia 62, autosomal recessive (SPG62)
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
  • 蛋白家族：
    Band 7/mec-2 family
  • 組織特異性：
    Expressed in heart, placenta, liver, kidney, pancreas, prostate, testis, ovary and small intestine.
  • 數據庫鏈接：

    HGNC: 16947

    OMIM: 611604

    KEGG: hsa:10613

    STRING: 9606.ENSP00000384900

    UniGene: Hs.150087



主站蜘蛛池模板： 九九久久精品免费观看| 私人毛片免费高清影视院| 久久精品丝袜高跟鞋| 亚洲乱码无人区卡1卡2卡3| 无码日日模日日碰夜夜爽| 大色综合色综合网站| 娇妻玩4p被三个男人伺候电影| 亚洲 欧美日韩 综合 国产| 中文人妻av久久人妻18| 国产日韩未满十八禁止观看| 欧美丰满熟妇xxxx性ppx人| 国产精品偷伦视频免费观看了| 亚洲熟妇久久精品| 无码h肉动漫在线观看免费| 牲高潮99爽久久久久777| 毛片内射-百度| 亚洲日韩精品a∨片无码| 色综合99久久久无码国产精品| 亚洲人成网站日本片| 日日大香人伊一本线久| 精品1卡二卡三卡四卡老狼| 青娱乐极品视觉盛宴国产视频| 国产福利姬喷水福利在线观看| 无码帝国www无码专区色综合| 人妻无码人妻有码中文字幕| 欧美熟妇性开放| 欧美变态另类牲交| 性饥渴的农村熟妇| 亚洲经典三级| 强制高潮18xxxx按摩| 国产高清在线精品一区二区三区 | 中国凸偷窥xxxx自由视频| 久久久久蜜桃精品成人片公司| 无码少妇精品一区二区免费| 五月丁香综合缴情六月小说| 爆乳高潮喷水无码正在播放| 日本免费一区二区三区| 国产精品自在在线午夜| 精品成人免费国产片| 久久99精品国产99久久6男男 | 亚洲欧洲日产韩国在线看片|