在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Ephrin-A3 (EFNA3)

  • 中文名稱:
    人EFNA3重組蛋白
  • 貨號(hào):
    CSB-YP007462HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    人EFNA3重組蛋白
  • 貨號(hào):
    CSB-EP007462HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    人EFNA3重組蛋白
  • 貨號(hào):
    CSB-EP007462HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人EFNA3重組蛋白
  • 貨號(hào):
    CSB-BP007462HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人EFNA3重組蛋白
  • 貨號(hào):
    CSB-MP007462HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    EFL 2; EFL-2; EFL2; EFN A3; EFNA 3; Efna3; EFNA3_HUMAN; EHK1 L; EHK1 ligand; EHK1-L; EHK1L; EPH related receptor tyrosine kinase ligand 3; EPH-related receptor tyrosine kinase ligand 3; Ephrin-A3; EphrinA3; EPLG 3; EPLG3; LERK 3; LERK-3; LERK3; Ligand of eph related kinase 3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    23-214
  • 氨基酸序列
    QGPGGALG NRHAVYWNSS NQHLRREGYT VQVNVNDYLD IYCPHYNSSG VGPGAGPGPG GGAEQYVLYM VSRNGYRTCN ASQGFKRWEC NRPHAPHSPI KFSEKFQRYS AFSLGYEFHA GHEYYYISTP THNLHWKCLR MKVFVCCAST SHSGEKPVPT LPQFTMGPNV KINVLEDFEG ENPQVPKLEK SISG
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
  • 基因功能參考文獻(xiàn):
    1. E2F3 and ephrin A3 are putative targets of miR-210, and their protein expression was up-regulated in the angiosarcoma cells PMID: 28739548
    2. Results show that EFNA3 serves as a tumor suppressor in malignant peripheral nerve sheath tumor cells and it may play a critical role in the FAK signaling and VEGF-associated tumor angiogenesis pathway. PMID: 25955218
    3. The present study provides evidence that microglia upregulates endothelial ephrin-A3 and ephrin-A4 to facilitate in vitro angiogenesis of brain endothelial cells, which is mediated by microglia-released TNF-alpha. PMID: 25070915
    4. EphA2/ephrin-A3 interactions may play a role in the localization and network of Langerhans cells in the epithelium and in the regulation of their trafficking. PMID: 12907451
    5. analysis of molecular surfaces in ephrin-A5 essential for a functional interaction with EphA3 PMID: 15901737
    6. MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. PMID: 18417479
    7. EphA3 mutants with constitutively-released kinase domains efficiently support shedding, even when their kinase is disabled. Our data suggest that this phosphorylation-activated conformational switch of EphA3 directly controls ADAM-mediated shedding. PMID: 19823572

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    Ephrin family
  • 組織特異性:
    Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 3223

    OMIM: 601381

    KEGG: hsa:1944

    STRING: 9606.ENSP00000357393

    UniGene: Hs.516656



主站蜘蛛池模板: 久久777国产线看观看精品| 老司机在线精品视频播放| 中文字幕无线观看中文字幕| 午夜三级a三级三点窝| 米奇影视第四色| 亚洲另类无码专区丝袜| 动漫精品专区一区二区三区| 亚洲熟女av综合网五月| a片免费视频在线观看| 无码人中文字幕| 国产亚洲精品久久久久秋霞不卡| 亚洲图片校园另激情类小说| 国产精品人妻一码二码| 婷婷色香五月综合激激情| r级无码视频在线观看| 亚洲日韩欧美一区久久久久我 | 欧美一区内射最近更新| 黑人粗大猛烈进出高潮视频| 天天躁夜夜躁狠狠综合2020| 粗大的内捧猛烈进出视频| 夜夜影院未满十八勿进| 永久免费的无码中文字幕| 国产精品无码永久免费888| 无码毛片一区二区本码视频| 欧美人与性囗牲恔配| 大学生高潮无套内谢视频| 国产在线高清理伦片a| 国产裸体xxxx视频在线播放| 国产偷v国产偷v亚洲高清| 97色伦图片97综合影院| 亚洲乱码日产一区三区| 国产自在自线午夜精品| 人人人妻人人澡人人爽欧美一区| 无码人妻久久一区二区三区| 亚洲国产欧美日韩精品一区二区三区| 久久久国产精品麻豆a片| 亚洲精品国产a久久久久久| 欧美 亚洲 国产 日韩 综aⅴ| 色欲天天婬色婬香视频综合网| 99精品视频在线观看免费| 色哟哟网站在线观看|