在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EFNA3 Antibody

EFNA3 Antibody

  • 中文名稱：
    EFNA3兔多克隆抗體
  • 貨號：
    CSB-PA561188
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA561188(EFNA3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA561188(EFNA3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    EFL 2 antibody; EFL-2 antibody; EFL2 antibody; EFN A3 antibody; EFNA 3 antibody; Efna3 antibody; EFNA3_HUMAN antibody; EHK1 L antibody; EHK1 ligand antibody; EHK1-L antibody; EHK1L antibody; EPH related receptor tyrosine kinase ligand 3 antibody; EPH-related receptor tyrosine kinase ligand 3 antibody; Ephrin-A3 antibody; EphrinA3 antibody; EPLG 3 antibody; EPLG3 antibody; LERK 3 antibody; LERK-3 antibody; LERK3 antibody; Ligand of eph related kinase 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human EFNA3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.
  • 基因功能參考文獻：
    1. E2F3 and ephrin A3 are putative targets of miR-210, and their protein expression was up-regulated in the angiosarcoma cells PMID: 28739548
    2. Results show that EFNA3 serves as a tumor suppressor in malignant peripheral nerve sheath tumor cells and it may play a critical role in the FAK signaling and VEGF-associated tumor angiogenesis pathway. PMID: 25955218
    3. The present study provides evidence that microglia upregulates endothelial ephrin-A3 and ephrin-A4 to facilitate in vitro angiogenesis of brain endothelial cells, which is mediated by microglia-released TNF-alpha. PMID: 25070915
    4. EphA2/ephrin-A3 interactions may play a role in the localization and network of Langerhans cells in the epithelium and in the regulation of their trafficking. PMID: 12907451
    5. analysis of molecular surfaces in ephrin-A5 essential for a functional interaction with EphA3 PMID: 15901737
    6. MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand Ephrin-A3. PMID: 18417479
    7. EphA3 mutants with constitutively-released kinase domains efficiently support shedding, even when their kinase is disabled. Our data suggest that this phosphorylation-activated conformational switch of EphA3 directly controls ADAM-mediated shedding. PMID: 19823572

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Ephrin family
  • 組織特異性：
    Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.
  • 數據庫鏈接：

    HGNC: 3223

    OMIM: 601381

    KEGG: hsa:1944

    STRING: 9606.ENSP00000357393

    UniGene: Hs.516656



主站蜘蛛池模板： 免费观看一区二区三区| 亚洲精品一区久久久久| 精品一卡2卡三卡4卡免费网站| 国产午夜福利视频在线观看| 亚洲va中文字幕| 亚洲成av人在线播放无码| 狠狠精品久久久无码中文字幕| 激情久久亚洲小说| 在线观看无码av网站永久免费| 丰满少妇人妻无码| 亚洲日韩国产成网在线观看| 国产日韩精品欧美2020区| 日产精品1区2区3区| 久久人人爽爽人人爽人人片av| 日本无码欧美一区精品久久| 国产精品沙发系列| 中文字幕精品亚洲无线码vr | 中字乱码视频| 国产日韩欧美亚欧在线| 国产免费一卡二卡三卡四卡| 日韩免费无码人妻波多野| 一本色道久久88亚洲精品综合| 蜜桃av抽搐高潮一区二区| 囯产精品久久久久久久久久妞妞| 成人影院yy111111在线| 麻豆精品久久久久久中文字幕无码| 激情爆乳一区二区三区| 亚洲欧美另类久久久精品能播放的| 天天干天天日| 亚洲 日韩 欧美 有码 在线| 香港三级日本三级韩级人妇| 内射国产内射夫妻免费频道| 午夜精品久久久内射近拍高清| 99精品丰满人妻无码a片| 中文无码日韩欧av影视| 国产成人精品无码免费看夜聊软件 | 国产aⅴ精品一区二区三区| 亚洲丰满熟女一区二区v| 国产在线拍偷自揄拍无码 | 97夜夜澡人人爽人人喊a| 人妻人人看人妻人人添|