在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Ectopic P granules protein 5 homolog (EPG5), partial

Recombinant Human Ectopic P granules protein 5 homolog (EPG5), partial

  • 中文名稱(chēng)：
    人EPG5重組蛋白
  • 貨號(hào)：
    CSB-YP881024HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人EPG5重組蛋白
  • 貨號(hào)：
    CSB-EP881024HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    人EPG5重組蛋白
  • 貨號(hào)：
    CSB-EP881024HU-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人EPG5重組蛋白
  • 貨號(hào)：
    CSB-BP881024HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人EPG5重組蛋白
  • 貨號(hào)：
    CSB-MP881024HU
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EPG5
  • Uniprot No.：
  • 別名：
    Ectopic P granules autophagy protein 5 homolog (C. elegans); Ectopic P granules protein 5 homolog; Epg5; EPG5_HUMAN; HEEW1; hEPG5; KIAA1632
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located.
  • 基因功能參考文獻(xiàn)：
    1. Our findings expand the phenotypical spectrum of EPG5-related Vici syndrome and suggest that this severe condition may already present in utero PMID: 28748650
    2. Our report further reinforces that EPG5-related Vici syndrome is both a neurodevelopmental disorder, which can be diagnosed as early as the second trimester of pregnancy, as well as a neurodegenerative disorder. PMID: 28168853
    3. The Vici syndrome protein EPG5 is a Rab7 effector that determines the fusion specificity of autophagosomes with late endosomes/lysosomes. PMID: 27588602
    4. Seven SNPs were significantly associated with the risk of Alzheimer disease, and eight SNPs were associated with the age at onset of AD. PMID: 27586004
    5. We report two sisters with a nonsense mutation within exon 14 of the EPG5 gene and a phenotype consistent with Vici syndrome PMID: 26854214
    6. This article confirms in silico predictions of aberrant splicing in the EPG5 gene due to the mutation NM_020964.2; c.1007A>G p.Gln336Arg PMID: 27343256
    7. A mutation affecting the penultimate exon of EPG5 and presenting with typical clinical manifestations of Vici syndrome. PMID: 25331754
    8. Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy. PMID: 23222957
    9. We characterized the KIAA1632 gene by computational methods: detailed investigation of the genomic structure, protein prediction, identification of orthologs in other species and phylogenetic analysis. PMID: 17549423

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Vici syndrome (VICIS)
  • 亞細(xì)胞定位：
    Cytoplasm, perinuclear region. Lysosome.
  • 蛋白家族：
    EPG5 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 29331

    OMIM: 242840

    KEGG: hsa:57724

    STRING: 9606.ENSP00000282041

    UniGene: Hs.514843



主站蜘蛛池模板： 印度女人狂野牲交| 国产精品xxx在线| 日日橹狠狠爱欧美超碰| 天天爽夜夜爽夜夜爽| 无码国产激情在线观看| 国产97人人超碰caoprom| 亚洲 制服丝袜 中文字幕 在线| 国产成人精品手机在线观看| 后入到高潮免费观看| 无码中文字幕在线播放2| 亚洲欧美日韩中文无线码| 亚洲亚洲熟妇色l图片20p| 一边做一边喷17p亚洲乱妇50p| 久久国产精品_国产精品| 青草草在线视频永久免费| 开心五月色婷婷综合开心网| 国产成人啪精品视频免费网站软件| 伊伊人成亚洲综合人网| av中文无码韩国亚洲色偷偷 | 国语自产偷拍精品视频蜜芽| 亚洲精品久久久久久久蜜桃臀| 久久棈精品久久久久久噜噜| аⅴ天堂中文在线网官网| 亚洲高清成人aⅴ片| 国产美女精品中文网蜜芽宝贝| 国产精品久久久久aaaa| 九一九色国产| 日韩精品一区二区三区vr| 国产成人av无码永久免费一线天 | 精品久久久无码中文字幕一丶| 精品国产一区二区三区久久久狼 | 免费国产成人高清在线视频| 国产成人精品午夜福利不卡| 东京热加勒比无码少妇| 7777久久亚洲中文字幕| 人妻丰满熟妇av无码片| 欧美日韩一本的免费高清视频| 国产精品成人3p一区二区三区| 久久久免费精品re6| 国产精品国产三级国产an| 人妻无码av中文系列久|