在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EPG5 Antibody

  • 中文名稱:
    EPG5兔多克隆抗體
  • 貨號(hào):
    CSB-PA384782
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
    • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:200
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    EPG5
  • 別名:
    Ectopic P granules autophagy protein 5 homolog (C. elegans) antibody; Ectopic P granules protein 5 homolog antibody; Epg5 antibody; EPG5_HUMAN antibody; HEEW1 antibody; hEPG5 antibody; KIAA1632 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthetic peptide from Human protein at AA range: 141-190
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 純化方式:
    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC,ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC IHC-p:1:50-300
    ELISA 1:10000-20000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located.
  • 基因功能參考文獻(xiàn):
    1. Our findings expand the phenotypical spectrum of EPG5-related Vici syndrome and suggest that this severe condition may already present in utero PMID: 28748650
    2. Our report further reinforces that EPG5-related Vici syndrome is both a neurodevelopmental disorder, which can be diagnosed as early as the second trimester of pregnancy, as well as a neurodegenerative disorder. PMID: 28168853
    3. The Vici syndrome protein EPG5 is a Rab7 effector that determines the fusion specificity of autophagosomes with late endosomes/lysosomes. PMID: 27588602
    4. Seven SNPs were significantly associated with the risk of Alzheimer disease, and eight SNPs were associated with the age at onset of AD. PMID: 27586004
    5. We report two sisters with a nonsense mutation within exon 14 of the EPG5 gene and a phenotype consistent with Vici syndrome PMID: 26854214
    6. This article confirms in silico predictions of aberrant splicing in the EPG5 gene due to the mutation NM_020964.2; c.1007A>G p.Gln336Arg PMID: 27343256
    7. A mutation affecting the penultimate exon of EPG5 and presenting with typical clinical manifestations of Vici syndrome. PMID: 25331754
    8. Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy. PMID: 23222957
    9. We characterized the KIAA1632 gene by computational methods: detailed investigation of the genomic structure, protein prediction, identification of orthologs in other species and phylogenetic analysis. PMID: 17549423

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Vici syndrome (VICIS)
  • 亞細(xì)胞定位:
    Cytoplasm, perinuclear region. Lysosome.
  • 蛋白家族:
    EPG5 family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 29331

    OMIM: 242840

    KEGG: hsa:57724

    STRING: 9606.ENSP00000282041

    UniGene: Hs.514843



主站蜘蛛池模板: 乱人伦视频中文字幕| 中文无码乱人伦中文视频在线v| 亚洲精品成人网站在线观看| 亚洲色大成网站www国产| 久久免费的精品国产v∧| 乱中年女人伦av| 四虎永久在线精品免费观看视频| 国产无遮挡免费真人视频在线观看 | 国产在线拍偷自揄拍无码| 182tv午夜福利在线地址二| 国产极品久久久久久久久| 国产av天堂亚洲国产av麻豆| 色偷偷人人澡人人爽人人模| 狠狠色狠狠色综合日日不卡| 欧美亚洲综合成人a∨在线 | 88久久精品无码一区二区毛片| 国内熟妇人妻色在线视频| 美女黄网站18禁免费看| 久久久精品人妻无码专区不卡| 色 亚洲 日韩 国产 综合| 中文字幕人妻无码专区| 久久亚洲精品无码av宋| 在线观看无码av免费不卡软件| 免费无码鲁丝片一区二区| 国产亚洲日韩在线三区| 亚洲图欧洲图自拍另类高清| 萝卜视频高清免费视频日本| 国产精品久久久久无码av色戒| 精品人体无码一区二区三区| 久久本色成人综合网| 国产免费不卡av在线播放| 成人爽a毛片免费| 久久人人爽人人爽人人片| 2019最新久久久视频精品| 亚洲精品人成网线在播放va | 国产a三级久久精品| 六月丁香亚洲综合在线视频| 国产萌白酱喷水视频在线观看| 日韩经典午夜福利发布| 日韩 欧美 国产 一区三| 午夜免费啪视频在线观看区 |