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Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3), partial

  • 中文名稱:
    人ENTPD3重組蛋白
  • 貨號:
    CSB-YP007692HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ENTPD3重組蛋白
  • 貨號:
    CSB-EP007692HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人ENTPD3重組蛋白
  • 貨號:
    CSB-EP007692HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ENTPD3重組蛋白
  • 貨號:
    CSB-BP007692HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人ENTPD3重組蛋白
  • 貨號:
    CSB-MP007692HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ENTPD3
  • Uniprot No.:
  • 別名:
    ATPDase; CD39 antigen like 3; CD39 antigen-like 3; CD39 like 3; CD39L3; Ecto apyrase; Ecto ATP diphosphohydrolase; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPase 3; Ecto-ATPDase 3; Ectonucleoside triphosphate diphosphohydrolase 3; ENTP3_HUMAN; ENTPD 3; ENTPD3; FLJ93839; HB 6; HB6; NTPDase 3; NTPDase3; OTTHUMP00000162079; OTTHUMP00000209227; OTTHUMP00000209228
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Has a threefold preference for the hydrolysis of ATP over ADP.
  • 基因功能參考文獻:
    1. NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors. PMID: 24085034
    2. NTPDase3 sequence revealed a high degree of structural fold similarity with a bacterial exopolyphosphatase PMID: 15966724
    3. efficiently inhibit the NTPDase3expressed in insulin secreting human pancreatic islet cells in situ PMID: 19120451
    4. Generation of a helical model for NTPDase3 suggests the importance of putative hydrogen bond interactions of conserved polar residues which are critical for enzyme expression, activity, and its susceptibility to membrane perturbations. PMID: 19743837
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    GDA1/CD39 NTPase family
  • 組織特異性:
    Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 3365

    OMIM: 603161

    KEGG: hsa:956

    STRING: 9606.ENSP00000301825

    UniGene: Hs.441145



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