在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ER membrane protein complex subunit 10 (EMC10), partial

In Stock
  • 中文名稱:
    人EMC10重組蛋白
  • 貨號:
    CSB-EP716413HU
  • 規(guī)格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    33.9 kDa
  • 表達區(qū)域:
    26-221aa
  • 氨基酸序列
    RGSGCRAGTGARGAGAEGREGEACGTVGLLLEHSFEIDDSANFRKRGSLLWNQQDGTLSLSQRQLSEEERGRLRDVAALNGLYRVRIPRRPGALDGLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLELFNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQEQKS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable). Promotes angiogenesis and tissue repair in the heart after myocardial infarction. Stimulates cardiac endothelial cell migration and outgrowth via the activation of p38 MAPK, PAK and MAPK2 signaling pathways.
  • 基因功能參考文獻:
    1. hHSS1-overexpression modulates signaling pathways involved in tumorigenesis. PMID: 25481245
    2. High-expression of hHSS1 is associated high-grade gliomas. PMID: 20680400
    3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    4. as a novel secreted protein, INM02 is associated with functions of pancreatic islets, especially of beta-cells PMID: 19570817
  • 亞細胞定位:
    [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
  • 蛋白家族:
    EMC10 family
  • 組織特異性:
    Present in serum (at protein level). Increased expression seen in the left ventrice after myocardial infarction (at protein level). Expressed in the pituitary gland; very low levels in other brain regions.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 27609

    OMIM: 614545

    KEGG: hsa:284361

    STRING: 9606.ENSP00000334037

    UniGene: Hs.448941



主站蜘蛛池模板: 日本xxxx片免费观看| 日本老熟妇乱| 熟女人妻少妇精品视频| 末成年毛片在线播放| 国产精品厕所| 亚洲 中文字幕 日韩 无码| 精品一区精品二区制服| 亚洲午夜成人久久久久久| 亚洲 一区二区 在线| 欧美xxxx黑人又粗又长| 国产白嫩美女在线观看| 女人的精水喷出来视频| 国产精品国产三级国av麻豆| 人妻无码系列一区二区三区| 综合亚洲桃色第一影院| 乱中年女人伦| 无码国产欧美一区二区三区不卡 | 亚洲成av人片在一线观看| 久久综合给合久久狠狠狠88| 久久人人97超碰国产精品| 青青草原综合久久大伊人精品| 免费超爽大片黄| 中文字幕丰满伦子无码| 一中文字幕日产乱码va| 上司的丰满人妻中文字幕| 影音先锋在线资源无码| 日本妇人成熟免费中文字幕| 色婷婷五月综合色啪网| 中国孕妇变态孕交xxxx| 5x性社区免费视频播| 欧美亚洲色aⅴ大片| 好男人在线社区www在线影院| 日本被黑人强伦姧人妻完整版| 免费看成人aa片无码视频| 麻豆国产原创视频在线播放| 偷国产乱人伦偷精品视频| 国产精品久久久久久久9999| 亚洲暴爽av人人爽日日碰| 亚洲自偷自拍另类11p| 亚洲欧美另类久久久精品| 国产麻豆 9l 精品三级站|